A5072815304- Adipose Tissue and Metabolism
- Cardiovascular Function and Risk Factors
- Cannabis and Cannabinoid Research
- Cardiomyopathy and Myosin Studies
- Natural Antidiabetic Agents Studies
- Neuroscience of respiration and sleep
- Cardiovascular Issues in Pregnancy
- Pain Mechanisms and Treatments
- Advanced Glycation End Products research
- Exercise and Physiological Responses
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Nanoparticles: synthesis and applications
- Cardiac Fibrosis and Remodeling
- Cardiovascular Effects of Exercise
- Curcumin's Biomedical Applications
- Moringa oleifera research and applications
- Animal Virus Infections Studies
- Advanced Materials and Semiconductor Technologies
- Ion Channels and Receptors
- Nerve injury and regeneration
- Modular Robots and Swarm Intelligence
- Medical and Biological Ozone Research
- Cardiovascular Disease and Adiposity
- Trypanosoma species research and implications
Universidad de Colima
2011-2025
Universidad de Sonora
2009-2015
University of Navojoa
2009-2014
Background: In recent years, the role of neurotrophins and their receptors in peripheral tissues has been great interest. At a metabolic level, brain-derived neurotrophic factor (BDNF) its receptor trkB have reported to participate insulin secretion from pancreas response increases circulating blood glucose. Objetive: To determines BDNF-trkB pathway pancreatic morphology rats fed cafeteria-style diet for 16 weeks. Methods: For study, male Wistar strain were divided into three groups as...
Hepatocellular carcinoma (HCC) is the most common primary liver cancer, often diagnosed at advanced stages due to insufficient early screening and monitoring. MicroRNAs (miRNAs) are key regulators of gene expression potential biomarkers for cancer diagnosis. This study investigated diagnostic miRNAs in Extracellular Vesicles (EVs) from HCC. miRNA EVs was analyzed using HCC cell lines, circulating a Diethylnitrosamine (DEN)-induced tumor rat model, plasma samples patients. Receiver Operating...
Different studies in experimental diabetes models suggest that zinc oxide nanoparticles (ZnONPs) are useful as antidiabetic agents. However, this evidence was performed and measured long-term treatments with repeated doses of ZnONPs. This work aimed to evaluate the ZnONPs acute effects on glycemia during next six h after an oral or intraperitoneal administration treatment healthy diabetic rats. In study, streptozotocin-nicotinamide male Wistar rats were used a model. 10 mg/kg did not modify...
The aim of this work was to determine whether Capsaicin may exert a vascular regulation through the activation CB1 and/or CB2 receptors causing vasorelaxation in rat aorta. Our results show location TRPV1 mainly endothelial and smooth muscle cells membrane. Nevertheless, caused artery mechanism independent TRPV1, since specific antagonists Capsazepine SB-366791 did not block effect Capsaicin. Because significant expression has been previously reported aorta, we used for these two prior...
The pathologic cardiac remodeling has been widely documented; however, the physiological induced by pregnancy and its reversion in postpartum are poorly understood. In present study we investigated changes collagen I (Col I) III III) mRNA protein levels left ventricle from rat heart during postpartum. Col expression samples were analyzed using quantitative PCR. Data obtained gene show that upregulated with contrast to expression, evaluated western blot showed is downregulated pregnancy....
Purpose: To investigate the antioxidant and phenolic profiles of methanol extracts from Rhizophora mangle L, Krameria erecta, Lycium berlandieri Dunal, Vallesia glabra Link Forchammeria watsonii Rose.Methods: The free radical 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method was used for assay plant extracts. Phenolic compounds determination carried out by high performance liquid cromatography (HPLC) using an analytical C18 column eluting with acetonitrile on a gradient program.Results: Extract L...
The function and morphology of β-cells is largely dependent on insulin demand. As cover a bigger cell proportion in pancreas islets, changes producer cells affect the whole pancreatic islet morphology. Growth factors as neurotrophins regulate physiology, besides; physical exercise increases sensitivity, further modifies brain derived neurotrophic factor (BDNF) concentration plasma. aim this study was to investigate effects chronic (running treadmill for 8 weeks) intensity morphometry healthy...
We evaluated changes in passive mechanical properties cardiac tissues during rat pregnancy. Left and right ventricular free walls were dissected from hearts of nonpregnant, late-pregnant, postpartum rats. Mechanical experiments strips done by stretch-release cycles using a step motor. The results show that pregnancy, there is hypertrophy associated with (1) an increase myocyte size, particularly augmented length, (2) decrease tension developed the myocardial walls, (3) both elastic modulus...
Background and objectives: Adipose tissue skeletal muscle secrete adiponectin, a hormone abundantly secreted by adipocytes, that through the adiponectin receptor, regulate glucose lipid metabolism. Adiponectin appears to protect muscles from inflammatory damage induced oxidative stress. It has been suggested decreased levels could be associated with pathologic conditions, including obesity diabetes. Furthermore, some studies suggest exercise have beneficial effect increasing levels, but this...
Rotavirus is the most common cause of gastroenteritis in children up to five years age worldwide. The aim present study was analyze genotypes rotavirus strains isolated from with gastroenteritis, after introduction vaccine México. detected 14/100 (14%) fecal samples using a commercial test kit. viral genome purified these and used as template RT-PCR amplification VP4 VP7 genes, followed by gene cloning sequencing. Among strains, 4/14 (28.5%) were characterized G12P[8], 2/14 (14.3%), G12P...
Background and objectives: Cardiac remodeling in pregnancy postpartum is poorly understood. The aim of this study was to evaluate changes cardiac fibrosis (pericardial, perivascular, interstitial), as well the expression matrix metalloproteinases (MMP-1, MMP-2, MMP-9) their inhibitors (Tissue metalloproteinases, TIMP-1 TIMP-4) during late rat left ventricle. Materials Methods: Female Sprague-Dawley rats were used for study. Rats divided three groups: non-pregnant, pregnancy, postpartum....
Pharmacological synergism is a current strategy for the treatment of pain. However, few studies have been explored to provide evidence possible between non-steroidal anti-inflammatory drug (NSAID) and cannabinoid agonist, in order establish which combinations might be effective manage The aim this study was explore ibuprofen (IBU) synthetic WIN 55,212-2 (WIN) improve pain relief by analyzing degree participation CB1 CB2 receptors antinociceptive using an experimental model Wistar rats....
Hepatocellular carcinoma (HCC) is the most common liver cancer, often diagnosed at advanced stages due to inadequate early diagnostic methods. MicroRNAs (miRNAs) play crucial roles in gene expression regulation and are possible biomarkers for molecular diagnosis several diseases, including cancer. This study aimed investigate potential of miRNAs contained Extracellular Vesicles (EVs) from HCC. The miRNA EVs was analyzed HCC cell lines, circulating a Diethylnitrosamine (DEN)-induced rat...
Background: The effect of pregnancy on skeletal muscle still has not been clearly established.The aim the present study was to investigate weight and contractile properties soleus plantaris muscles.Methods: female Sprague-Dawley rats were divided into two groups: nonpregnant (NP, 250 ± 4 g, n = 8) late-pregnant (LP, 305 13 8).The right muscles liberated from surrounding tissues.Each placed setup mechanical recording with electric stimulation.In optimum length each recorded single twitches,...
ZnO nanoparticles (ZnONPs) have been shown to therapeutic potential in some diseases such as diabetes and cancer. However, concentration-dependent adverse effects also reported. Studies which evaluate the of ZnONPs on cardiovascular system are scarce. This study aimed a low dose administered chronically healthy rats. Changes dyslipidemia biomarkers, blood pressure, aortic wall structure, vascular contractility, expression cannabinoid receptors aorta were evaluated. Healthy rats divided into...