A5089710865- Nanoparticles: synthesis and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Extracellular vesicles in disease
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Essential Oils and Antimicrobial Activity
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lipid Membrane Structure and Behavior
- Nanopore and Nanochannel Transport Studies
- Electrostatics and Colloid Interactions
- Blood properties and coagulation
- Surfactants and Colloidal Systems
- Atherosclerosis and Cardiovascular Diseases
- Immunotherapy and Immune Responses
- Spectroscopy and Quantum Chemical Studies
- MicroRNA in disease regulation
- Phytochemicals and Medicinal Plants
- Chemistry Education and Research
- Advanced Nanomaterials in Catalysis
- Nanocluster Synthesis and Applications
- Wound Healing and Treatments
- Geophysical and Geoelectrical Methods
- Proteins in Food Systems
- Electrowetting and Microfluidic Technologies
- DNA and Nucleic Acid Chemistry
Universidad de Sonora
2006-2025
Universidad de Granada
2009-2012
Universidad Complutense de Madrid
2009
Centro de Investigaciones Biológicas Margarita Salas
2009
Universidad de Jaén
2009
Synthesis of gold nanoparticles (AuNPs) with plant extracts has gained great interest in the field biomedicine due to its wide variety health applications. In present work, AuNPs were synthesized Mimosa tenuiflora (Mt) bark extract at different metallic precursor concentrations. Mt was obtained by mixing tree ethanol-water. The antioxidant capacity evaluated using 2,2-diphenyl-1-picrylhydrazyl and total polyphenol assay. characterized transmission electron microscopy, X-ray diffraction,...
Abstract In this work we use Mimosa tenuiflora (MtE) extracts as reducing agents to synthesize silver nanoparticles (AgMt NPs) which were characterized by DPPH and Total Polyphenols Assays, UV–visible, X-ray diffractometer (XRD), high-resolution transmission electron microscopy (HRTEM), photoelectron spectroscopy (XPS) Thermogravimetric analysis (TGA). AgMt NPs possess average sizes of 21 nm fcc crystalline structure, it was also confirmed that the MtE is present in even after cleaning...
Hepatocellular carcinoma (HCC) is the most common primary liver cancer, often diagnosed at advanced stages due to insufficient early screening and monitoring. MicroRNAs (miRNAs) are key regulators of gene expression potential biomarkers for cancer diagnosis. This study investigated diagnostic miRNAs in Extracellular Vesicles (EVs) from HCC. miRNA EVs was analyzed using HCC cell lines, circulating a Diethylnitrosamine (DEN)-induced tumor rat model, plasma samples patients. Receiver Operating...
Due to their biocompatibility and non-toxicity, biopolymer-based films hold significant importance in bioengineering. It is imperative comprehend the influence of chitosan molecular weight filler materials nature on crystalline structure subsequent effect film properties. The aim this research was determine how carbon nanotubes embedded within can significantly improve performance produced by solvent-casting technique. Four probe measurements demonstrated that medium-molecular-weight...
The compaction of DNA by cationic liposomes constituted a mixture lipid, dioctadecyldimethylammonium bromide (DODAB), and zwitterionic 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) or 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC), has been evaluated means experimental studies (electrophoretic mobility, conductometry, cryogenic electron transmission microscopy cryo-TEM, fluorescence spectroscopy) as well theoretical calculations. This information reveals that DODAB/DOPE...
We present experimental and simulation evidence for a new mechanism of charge reversal operating only ions capable to penetrate into soft interfaces. It is based on the preferential solvation counterions by amphiphilic molecules hydration water rather than bulk water. This does not require high surface densities it affected addition 1:1 salt. behavior opposite that observed in systems as diverse microfluidic channels or latex colloids. The robustness physiological amounts salt suggests...
In this work, we used a sequential method of synthesis for gold-silver bimetallic nanoparticles with core@shell structure (Au@AgNPs). Rumex hymenosepalus root extract (Rh), which presents high content in catechins and stilbenes, was as reductor agent synthesis. Size distribution obtained by Transmission Electron Microscopy (TEM) gives mean diameter 36 ± 11 nm Au@AgNPs, 24 4 gold (AuNPs), 13 3 silver (AgNPs). The geometrical shapes NPs were principally quasi-spherical. thickness the shell...
The objective of this research work is to understand the effect surface charge density on reversal phenomenon. To end, we use experimental results and computer simulations. In particular, measure electrophoretic mobility latex particles (macroions) in presence a multivalent electrolyte. We have focused electrolyte concentration range at which expected happen. role process looked into from several latexes with same functional group but different densities. Although mechanism responsible for...
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease. Lesions in the epithelium cause alterations microenvironment that promote fibroblast accumulation. Extracellular vesicles (EVs) transport proteins, lipids, and nucleic acids, such as microRNAs (miRNAs). The aim of this study was to characterize differentially expressed miRNAs cargo EVs obtained from LL97 LL29 cell lines isolated IPF lungs versus those derived CCD19 line healthy donors. We characterized by...
We synthesized silver nanoparticles using Rumex hymenosepalus root extract (Rh). Nanoparticles were subjected to a purification process and final product is composite of Rh (AgNPsC). Transmission electron microscopy (TEM), high-resolution transmission (HRTEM), X-ray diffraction (XRD), photoelectron spectroscopy (XPS) used perform microstructure study. Additionally, two fractions (RhA RhB) obtained from the original by filtration with tetrahydrofuran (THF); both analyzed UV-Vis spectroscopy,...
Early Mortality Syndrome (EMS) or Acute Hepatopancreatic Necrosis (AHPNS) is a disease produced by gram-negative bacteria Vibrio parahaemolyticus ( V. ), which has caused declines in worldwide production of white shrimp Litopenaeus vannamei L. ). In this work, we propose the implementation silver nanoparticles (AgNPs) synthesized with Rumex hymenosepalus (Rh) extract as an alternative on control. AgNPs were characterized UV-Vis spectroscopy, scanning electron microscopy (SEM), transmission...
The study, synthesis, and application of nanomaterials in medicine have grown exponentially recent years. An example this is the understanding how activate or regulate immune system, particularly macrophages. In work, nanoparticles were synthesized using Rumex hymenosepalus as a reducing agent (AgRhNPs). According to thermogravimetric analysis, metal content 55.5% by weight. size particles ranges from 5–26 nm, with an average 11 they possess fcc crystalline structure. presence extract...
A green method for synthesizing gold nanoparticles is proposed using hydroethanolic extract of Vitex mollis fruit (Vm extract) as a reducer and stabilizer. The formation synthesized with Vm (AuVmNPs) was monitored by measuring the ultraviolet–visible spectra. morphology crystalline phase were determined scanning electron microscopy, X-ray diffraction, high-resolution transmission microscopy. Synthesized generally spherical, size distribution obtained microscopy shows two populations mean...
Background: The goal of this study was to analyze the in vitro effect plasma-isolated extracellular vesicles (EVs) from patients with impaired fasting glucose (IFG) on cell migration and angiogenic score human endothelial cells (EA.hy926) cultures. Methods: Plasma samples five IFG, Type 2 diabetes mellitus (T2DM), normoglycemic subjects (controls) were used. Plasma-derived EVs characterized by electron microscopy, dynamic light scattering Western blotting, vascular growth factor receptor...
Hepatocellular carcinoma (HCC) is the most common liver cancer, often diagnosed at advanced stages due to inadequate early diagnostic methods. MicroRNAs (miRNAs) play crucial roles in gene expression regulation and are possible biomarkers for molecular diagnosis several diseases, including cancer. This study aimed investigate potential of miRNAs contained Extracellular Vesicles (EVs) from HCC. The miRNA EVs was analyzed HCC cell lines, circulating a Diethylnitrosamine (DEN)-induced rat...
The search of new genetic vectors that improve the efficacy gene delivery into diseased cells has led to creation several vector formulations promote effectiveness in applications. However, DNA affinity as well vector/DNA complex stability remains a problem be solved. Here, we study lipoplexes made DODAB‐DOPC cationic liposomes (CL) and calf thymus (ctDNA) preliminary cargo model novel formulation affinity. Physicochemical characterization was carried out by Z ‐potential ( ζ ), light...
Aims: Erythrocruorin is considered for a potential application as Red Blood Cells Substitute. Background: Nanostructured materials such liposomes and polymeric have offered new alternatives that allow the design of systems substitutes red blood cells. Objective: Functionalized fabrication characterization. Methods: The manufactured with egg yolk lecithin prepared by extrusion method were functionalized EfEc stabilized polyethylene glycol (PEG) an absorption method. Results: nanoplatform has...
Abstract In this work, we used a sequential method of synthesis for gold-silver bimetallic nanoparticles with core@shell structure (Au@AgNPs). Rumex hymenosepalus root extract (Rh), which presents high content in catechins and stilbenes, was as reductor agent synthesis. Size distribution obtained by Transmission Electron Microscopy (TEM) give diameter mean 36 nm Au@AgNPs, 24 gold (AuNPs). The geometrical shapes NPs were principally quasi-spherical. thickness silver shell over AuNPs are...