A5082474021- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Traditional and Medicinal Uses of Annonaceae
- Natural product bioactivities and synthesis
- Phytochemical compounds biological activities
- Phytochemistry and Biological Activities
- Plant biochemistry and biosynthesis
- Bioactive Compounds and Antitumor Agents
- Essential Oils and Antimicrobial Activity
- Cocoa and Sweet Potato Agronomy
- Microbial Natural Products and Biosynthesis
- Phytochemistry and Bioactive Compounds
- Natural Antidiabetic Agents Studies
- Synthesis of Organic Compounds
- Sesquiterpenes and Asteraceae Studies
- Advanced Glycation End Products research
- Marine Sponges and Natural Products
- Pathogenesis and Treatment of Hiccups
- Phytochemicals and Antioxidant Activities
- Plant chemical constituents analysis
- Antimicrobial agents and applications
- Cancer, Stress, Anesthesia, and Immune Response
- Estrogen and related hormone effects
- Botanical Research and Applications
- Drug-Induced Ocular Toxicity
Universidad de Colima
2014-2024
Universidad Nacional Autónoma de México
2003-2009
Annona purpurea, known in Mexico as "cabeza de negro" or "ilama", belongs to the Annonaceae family. Its roots are employed folk medicine several regions of Mexico. Taking that information into account, a chemical and biological analysis components present this species was proposed. Our results demonstrated dichloromethane (DCM) extract exclusively constituted by mixture five new acetogenins named annopurpuricins A-E (1-5). These compounds have an aliphatic chain 37 carbons with terminal α,β...
Different studies in experimental diabetes models suggest that zinc oxide nanoparticles (ZnONPs) are useful as antidiabetic agents. However, this evidence was performed and measured long-term treatments with repeated doses of ZnONPs. This work aimed to evaluate the ZnONPs acute effects on glycemia during next six h after an oral or intraperitoneal administration treatment healthy diabetic rats. In study, streptozotocin-nicotinamide male Wistar rats were used a model. 10 mg/kg did not modify...
A selective, sensitive and precise reversed phase HPLC-DAD method was developed validated for the simultaneous determination of six phenolic acids in aqueous extract their hydrolyzed forms prepared from Solanum elaeagnifolium Cav., Solanaceae, Ampelocissus acapulcensis (Kunth) Planch., Vitaceae, or Brosimum alicastrum Sw., Moraceae. The new showed good linearity (r > 0.999) a relatively wide concentration range (0.5–100 mg/l). limits detection quantification compounds were 0.097–0.467 mg/l...
Annona purpurea is a species known in Mexico as "cabeza de negro". In folk medicine A. root used to treat patients with kidney diseases and cancer. Our recent studies demonstrated that this contains five acetogenins named annopurpuricins A-E, which are active against tumoural cell lines subnanomolar range.To develop an analytical method using high-performance liquid chromatography diode array detector (HPLC-DAD) quantify A-E different samples.To the sample treatment was carried out,...
From the aerial parts of Decatropis bicolor, heraclenin (1), seselin (2), psoralen (3), imperatorin (4), skimmianine (5), and heraclenol (6), were isolated. This is first time that coumarin-like compounds are isolated from genus. The anti-inflammatory properties 1–6 examined against ear edema in mice produced by TPA. results suggest activity each compound depends its individual substitution on aromatic ring rather than coumarin skeleton itself.
Breast cancer (BC) is the most common and main cause of mortality due to in women around World. Histone deacetylase 6 (HDAC6) a promising target for treatment BC. In present study, series novel 3‑carboxy‑coumarin sulfonamides, analogs belinostat, targeting HDAC6 were designed synthesized. The compounds synthesized purified through open‑column chromatography. Characterization was performed using spectroscopic techniques, including <sup>1</sup>H <sup>13</sup>C NMR, homonuclear heteronuclear...
Three new N-benzoyltyramides derivatives named pubesamides A, B and C together with the known skimmianine, β -sitosterol daucosterol were isolated from seeds of C. pubescens. Their structures determined by spectroscopic data.
Anthropological research indicates that Brosimum alicastrum seed, also known as Ramón tree or mojo was one of the staple foods pre-Columbian people. Because world population growth demand alternative source food, there is an increasing use B. alicastrum, especially in American continent. In order to contribute its rational use, this presents, biochemical and functional characterization albumins globulins. Our results demonstrated these storage proteins are most abundant protein fractions....
The title compound, (20S,24R)-incanilin, C30H48O4, contains three six-membered rings and two five-membered rings. ring B adopts a distorted envelope conformation D twist conformation. In the crystal structure, molecules exist as O—H⋯O hydrogen-bonded dimers.
In recent years, different studies carried out in experimental diabetes models suggest that zinc oxide nanoparticles (ZnONPs) can be good antidiabetic agents, this evidence was obtained from long-term treatments using repeated doses of nanoparticles. The goal work to evaluate the acute effects during six hours post-administration ZnONPs on glycemia healthy and diabetic rats compare oral intraperitoneal administration. For study male Wistar were used induced by streptozotocin-nicotinamide At...