- Protease and Inhibitor Mechanisms
- Cervical Cancer and HPV Research
- Cancer, Lipids, and Metabolism
- Inflammatory mediators and NSAID effects
- Urological Disorders and Treatments
- COVID-19 Clinical Research Studies
- Blood Coagulation and Thrombosis Mechanisms
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Adipose Tissue and Metabolism
- Genital Health and Disease
- Prostate Cancer Treatment and Research
- Lipoproteins and Cardiovascular Health
- Amyotrophic Lateral Sclerosis Research
- Pancreatic function and diabetes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Hydrogen's biological and therapeutic effects
- RNA Interference and Gene Delivery
- Urinary and Genital Oncology Studies
- Viral Infections and Vectors
- Invertebrate Immune Response Mechanisms
- Lipid metabolism and disorders
- TGF-β signaling in diseases
- Muscle metabolism and nutrition
- Pregnancy and Medication Impact
Universidad de Colima
2013-2022
Universidad de Guadalajara
2011-2019
Cervical human papillomavirus (HPV+) infection is associated with an increased risk of cervical dysplasia. Although the frequency HPV+ in systemic lupus erythematosus (SLE) has been investigated some races its prevalence Hispanic women still unknown. This cross-sectional study evaluated Mexican SLE ( n = 34) or rheumatoid arthritis (RA) 43) and healthy controls 146). These were interviewed about factors for sexually transmitted infections cytology analysis was performed. viral types...
Coronavirus disease 2019 (COVID‑19) is currently the major public health problem worldwide. Neutral electrolyzed saline solution that contains reactive chlorine and oxygen species may be an effective therapeutic. In present study, treatment efficacy of intravenous and/or nebulized neutral combined with usual medical care vs. alone was evaluated in ambulatory patients COVID‑19. A prospective, 2‑arm, parallel‑group, randomized, open‑label, multi‑center, phase I‑II clinical trial including 214...
Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity on matrix proteins, particularly basement membrane constituents. A single nucleotide polymorphism C>T transition at -1306 displayed a strong association several cancers. Our study investigated whether or not the MMP-2 -1306C>T contributed to development of breast cancer (BC) in Mexican population.90 patients BC and 96 control subjects were analyzed detect polymorphism.The frequency CC genotype was significantly higher...
Breast cancer is the most common gynecologic malignancy known worldwide. The consumption of certain foods may modify risk for its development. Peanuts and other seeds have shown anticarcinogenic effects in vitro, but there are a few studies that evaluate effect their on development breast cancer. aim present study was to determine whether an association between peanuts, walnuts, almonds cancer.We analyzed 97 patients presenting with 104 control subjects did not pathology (BIRADS 1-2). An...
Background: Coronavirus disease (COVID-19) is currently the main public health problem worldwide. The administration of neutral electrolyzed saline, a solution that contains reactive species chlorine and oxygen (ROS), may be an effective therapeutic alternative due to its immunomodulating characteristics, in systemic inflammation control, as well immune response improvement, promoting control viral infection. present study evaluated efficacy treatment with intravenous and/or nebulized saline...
Prostate cancer (PCa) is the second most common non-dermatological in men and a growing public health problem. Castration-resistant disease (CRD) advanced stage of difficult to control. Patients with CRD may no longer accept conventional therapies as they are not appropriate clinical conditions or refuse receive it. Given that inflammation an essential component origin progression, anti-inflammatory agents could be therapeutic option fenamates one proposed choices. A prospective, randomized,...
Dengue virus (DENV) is currently considered as one of the most important mosquito-borne viral pathogens affecting humans. Genetic variations in viruses are likely to be a condition for more effective evasion immune system and resulting severe clinical consequences. The DENV‑1 NS5 gene was sequenced establish whether during an epidemic burst there were genetic any variant associated (through case‑control design) with behavior. A total 31 patients positive enrolled. Among nucleotide...
Introduction The expression of plasminogen activator inhibitor type 1 (PAI-1), vascular endothelial growth factor (VEGF), and transforming β1 (TGF-β1) participates in the angiogenesis several cancer types. goal this study was to investigate polymorphisms genes related (PAI-1-675 4G/5G, VEGF C936T, TGF-β1 G-800A) evaluate risk for developing uterine cervical (UCC). Methods In a case-control study, 100 healthy subjects patients with UCC from Mexico were included. We determined genetic profile...
Abstract Background Obesity in children and adolescents has increased alarmingly, placing them at a higher risk for impaired glucose tolerance type 2 diabetes. The prevalence of vitamin D deficiency as well. Vitamin is critical homeostasis insulin secretion. Studies on adults have reported an inverse association between levels resistance (IR), but the results are inconsistent. aim our study was to determine IR serum obese Mexican adolescents. Methods A cross-sectional performed 227 6 19...
Carnitine palmitoyltransferase IB (CPT1B) and adrenoceptor beta-3 (ADRB3) are critical regulators of fat metabolism. CPT1B transports free acyl groups into mitochondria for oxidation, ADRB3 triggers lipolysis in adipocytes, their respective polymorphisms E531K W64R have been identified as indicators obesity population studies. It is therefore important to understand the effects these mutations on function adipose skeletal muscle tissue, respectively. This study aimed analyze rate plasma...