A5067353337- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Nasal Surgery and Airway Studies
- Allergic Rhinitis and Sensitization
- Cystic Fibrosis Research Advances
- Infectious Diseases and Mycology
- Oral and Maxillofacial Pathology
- Bone Tumor Diagnosis and Treatments
- Cerebrospinal fluid and hydrocephalus
- Asthma and respiratory diseases
- Dental Research and COVID-19
- Tracheal and airway disorders
- Olfactory and Sensory Function Studies
- SARS-CoV-2 and COVID-19 Research
- Respiratory and Cough-Related Research
- Mycobacterium research and diagnosis
- Antifungal resistance and susceptibility
- Obstructive Sleep Apnea Research
- Meningioma and schwannoma management
- SARS-CoV-2 detection and testing
- Airway Management and Intubation Techniques
- Pituitary Gland Disorders and Treatments
- Autoimmune Bullous Skin Diseases
- Surgical Simulation and Training
- Polyomavirus and related diseases
University of British Columbia
2013-2024
St. Paul's Hospital
1996-2020
St. Paul's Co-educational College
2015
Georgia Nasal and Sinus Institute
2000-2003
University of Alabama at Birmingham
2001
Objective To investigate the frequency and nature of adverse events related to type 2 biologic use in patients with chronic rhinosinusitis nasal polyps (CRSwNP), including dupilumab mepolizumab. Methods This is a single‐institution retrospective study real‐world patient data. Patients were included if they have diagnosis CRSwNP, undergone at least one endoscopic sinus surgery, taken two doses or mepolizumab between January 1, 2016, July 2023. Data collected include clinicodemographic...
Allergic fungal sinusitis (AFS), first described over 18 years ago and subsequently identified using established criteria, remains a challenge to treat. Our protocol has included complete functional endoscopic sinus surgery remove the load restore physiologic mucous clearance. The patient is treated with prednisone for several months followed monthly total serum IgE levels an mucosal staging system. A group of 11 patients in 1994 presented at 1995 American Rhinology Society Spring meeting...
La rhinite est une affection frequente, documentee chez pres de 40% la population. allergique en particulier frequente dans population et certaines etudes semblent indiquer augmentation son incidence. Depuis les dernieres recommandations canadiennes 1994, nous avons fait des progres considerables comprehension processus inflammatoires impliques presentation clinique rhinite. De plus, nouvelles modalites therapeutiques sont maintenant disponibles. Il aussi etabli que peut etre plus qu'un...
Sinonasal inverted papillomas (SNIPs) are benign epithelial growths with high recurrence rates after surgical management. This study aims to evaluate SNIP endoscopic surgery and provide a comparison of published staging systems.This chart review evaluated primary revision cases from January 2008 December 2016 at tertiary sinus centre. Data was collected on patient demographics, origin site, approaches, follow-up duration, recurrence, smoking history. Each case staged using Krouse, Oikawa,...
To curb the spread of SARS-CoV-2, etiologic agent COVID-19 pandemic, we characterize virucidal activity long-acting Povidone Iodine (PVP-I) compositions developed using an in-situ gel forming technology. The PVP-I nasal spray (IVIEW-1503) and ophthalmic eye drop (IVIEW-1201) rapidly inactivated inhibiting viral infection VERO76 cells. No toxicity was observed for formulations. Significant inactivation noted with preincubation virus these formulations at lowest concentrations tested. It has...
Background: 3-Dimensional (3D) printing has proven its role in various fields. Recently, 3D also been introduced the otolaryngology domain. The nasopharynx, paranasal sinuses, and anterior skull base have a complex anatomy. Critical structures must be delicately protected preserved during surgical procedure. It is, therefore, very important for surgeon to an excellent spatial understanding of field that is being traversed. Case Description: Our case 19-year-old male with 2-month history...
There have been very few reports describing postlung transplant outcomes in patients’ infected/colonized with Burkholderia gladioli pretransplant. A case involving a lung recipient cystic fibrosis who ultimately died as result of severe rhinosinusitis due to B infection the context immunosuppression is reported.
Many reconstructive techniques and materials have been reported for repair of skull base defects after sinonasal tumor excision, cerebrospinal fluid (CSF) leaks, coverage denuded bone. Synthetic developed endoscopic to avoid donor-site morbidity. Polydioxanone plate is a bioabsorbable implant designed nasal septal reconstruction has the ability retain strength at least 10 weeks absorbs in 6 months.This study aimed describe use polydioxanone plates defect CSF leak repair, our experience with...
Background Allergic Fungal Rhinosinusitis (AFRS) is a non-invasive fungal disease that results from chronic allergic inflammation of the sinonasal mucosa. Failure to respond mainstay medical therapies and sinus surgery leaves AFRS patients with limited alternatives decreased quality life. Mepolizumab known IL-5 antagonist for severe eosinophilic asthma. Objective To identify efficacy mepolizumab on improving Modified Lund-Kennedy (MLK) endoscopic scores in recalcitrant Methods Retrospective...
Numerous reconstructive techniques and materials have been reported for repair of skull base defects, cerebrospinal fluid (CSF) leaks, coverage denuded bone, including pedicled vascularized flaps free mucosal grafts.This study described our technique harvesting transferring a nasal floor mucoperiosteal graft discussed experience with the application this technique.A retrospective review 19 patients (mean age, 53.7 years; 13 men, 6 women) treated image-guided endoscopic sinus surgery chronic...
Ectopic olfactory neuroblastoma (ONB) is a rare neuroendocrine sinonasal malignancy which arises from regions where neuroepithelium does not exist. Presentation of syndrome inappropriate antidiuretic hormone release (SIADH) in patients with ectopic ONB extremely rare. We report case 22-year-old patient and paraneoplastic SIADH that was managed at our center. The arising the left lamina papyracea extending into maxillary ethmoid sinuses filling nasal cavity. Correction sodium levels occurred...
Abstract Objectives/Hypothesis To assess the efficacy of 0.23% povidone-iodine (PVP-I) nasal rinses and mouth washes on detectability coronavirus disease 2019 (COVID-19) virus cycle threshold (Ct) values in nasopharyngeal swabs. Study design This was an open-label, prospective, randomized, placebo-controlled clinical trial. Setting The study conducted King Saud University Medical City, Riyadh, Saudi Arabia, from August 2021 to July 2022. Methods Participants diagnosed with SARS-CoV-2 were...
Background Fibrosarcomas of the paranasal sinuses and skull base are uncommon tumors. Traditionally, “open approach” surgery remains mainstay for treatment choice these Methods A 49-year-old man underwent resection a right anterior fibrosarcoma using endoscopic approach. Results Close follow-up both imaging methods over period four years has revealed well-healed with no evidence recurrence. Conclusion Significant resistance exists at present such technique to deal malignant diseases head...
Esthesioneuroblastoma is a rare neoplasm typically arising from olfactory neuroepithelium of the superior nasal cavity.1, 2 demonstrates bimodal age distribution, with peaks in second to third, as well sixth seventh, decades life.3 Patients often complain nonspecific sinonasal symptoms, including unilateral obstruction, headache, and epistaxis.2 represents 3% all tumors; however, its prevalence likely underestimated due delayed recognition.2, 3 Atypical clinical features arise cases ectopic...