A5102767626- Advanced Sensor and Energy Harvesting Materials
- Analytical chemistry methods development
- Ferroptosis and cancer prognosis
- Microfluidic and Capillary Electrophoresis Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Telomeres, Telomerase, and Senescence
- Graphene research and applications
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- MXene and MAX Phase Materials
- Cancer Immunotherapy and Biomarkers
- Catalytic C–H Functionalization Methods
- Oxidative Organic Chemistry Reactions
- Supercapacitor Materials and Fabrication
- Conducting polymers and applications
- Single-cell and spatial transcriptomics
- Immune cells in cancer
- Advanced Materials and Mechanics
- Ionic liquids properties and applications
- Silk-based biomaterials and applications
- Fire dynamics and safety research
- Seaweed-derived Bioactive Compounds
- Polydiacetylene-based materials and applications
- Polymer Surface Interaction Studies
- Liquid Crystal Research Advancements
Tiangong University
2023-2025
Shandong First Medical University
2024
University of Science and Technology of China
2009-2024
Nankai University
2007-2023
State Key Laboratory of Medicinal Chemical Biology
2021-2022
Chinese PLA General Hospital
2022
Qingdao National Laboratory for Marine Science and Technology
2017-2018
Ocean University of China
2017-2018
Abstract Natural gels and biomimetic hydrogel materials have been able to achieve outstanding integrated mechanical properties due the gain of natural biological structures. However, nearly every structure relies on water as solvents or carriers, which limits possibility in extreme conditions, such sub-zero temperatures long-term application. Here, peptide-enhanced eutectic were synthesized by introducing α-helical “molecular spring” into deep solvent. The gel takes full advantage structure,...
Abstract The exceptional physical properties and unique layered structure of two-dimensional (2D) materials have made this class great candidates for applications in electronics, energy conversion/storage devices, nanocomposites, multifunctional coatings, among others. At the center application space, mechanical play a vital role design, manufacturing, integration performance. emergence 2D has also sparked broad scientific inquiry, with new understanding interactions between structures...
Two-dimensional conductive metal-organic frameworks (2D CMOFs) can be regarded as high-performance electrode substances owing to their rich hierarchical porous architecture and excellent electrical conductivity. However, the sluggish kinetics behavior of electrodes within bulk structure restricts advances in energy storage fields. Herein, a series graphene-based mixed-dimensional composite aerogels are achieved by incorporating 2D M-tetrahydroxy-1,4-quinone (M-THQ) (M = Cu, Cu/Co, or Cu/Ni)...
Abstract Described here is the first example of a rhodium‐catalyzed carboacylation/aromatization cascade C=O bond by C−C activation. In this transformation, reactive rhodaindanone complex regioselectively generated and adds across with subsequent elimination, thus providing unique strategy to access multisubstituted benzofuran scaffold. A diverse range analogues were obtained in good yields. Mechanistic studies show tricyclic lactone was viable intermediate. Application methodology total...
Anisotropic two-dimensional materials present a diverse range of physical characteristics, making them well-suited for applications in photonics and optoelectronics. While mechanical properties play crucial role determining the reliability efficacy 2D material-based devices, fracture behavior anisotropic crystals remains relatively unexplored. Toward this end, we herein first measurement toughness Ta2NiSe5 by microelectromechanical system-based tensile tests. Our findings reveal significant...
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Abstract Magnetite nanoparticles (Fe 3 O 4 NPs) with molecular recognition capabilities offer significant potential for biomedical applications, yet existing surface protein imprinting methods often suffer from low efficiency. Herein, a enzyme‐mediated polymerization strategy is exploited of bovine serum albumin (BSA) onto Fe NPs. This method, compatible all vinyl monomers and operable under mild conditions, enables at high monomer concentrations while preventing nanoparticle agglomeration....
Abstract. Heavy regional particulate matter (PM) pollution in China has resulted an important and urgent need for joint control actions among cities. It is advisable to improve the understanding of background concentration PM development efficient effective policies. With increase height influence source emission on local air quality decreases with altitude, but characteristics gradually become obvious. A method estimate proposed this paper, based vertical periodic variation atmospheric...
Abstract Aging is an inevitable consequence of life, characterized by a progressive decline in tissue and organ function increased risk death. There growing evidence that aging closely related to tumor development immune regulation. However, hepatocellular carcinoma, the relationship between cellular senescence infiltration, energy metabolism, chemokines, immunotherapeutic response unclear needs further study. We first analyzed 274 senescence-associated genes NMF algorithm identified two...
A novel ureidobromophenol, rhodomelin (1), was characterized from Rhodomela confervoides. Its structure elucidated by spectroscopic analysis. Both enantiomers of 1 were synthesized using a convergent strategy starting d/l-pyroglutamic acids, respectively, allowing assignment the R-configuration for naturally occurring isomer chiral HPLC Rhodomelin represents first example ureidopyrrolidone alkaloid incorporating γ-aminobutyric acid unit. The scavenging activity toward DPPH...
Low-cost and highly effective methods are desirable to replace the costly ethanol fractionation affinity chromatography in IgG isolation from human plasma. Molecularly imprinted polymers (MIPs) of potential candidates, however, they still suffer severe problems such as difficult template removal low imprinting efficiency. Here, a recently developed strategy was adopted overcome these problems. The MIPs were synthesized using poly(L-glutamic acid) (PLGA) peptide crosslinkers instead commonly...
Immunotherapy has yielded encouraging results in the treatment of advanced hepatocellular carcinoma (HCC). However, relationship between epithelial-mesenchymal transition (EMT) and immunotherapy for HCC not been adequately explained. In this study, we comprehensively analyzed a bulk RNA sequence dataset 365 patients The Cancer Genome Atlas (TCGA) dataset. Subsequently, constructed prognostic signature based on 6 EMT-related genes divided into high- low-risk groups. predictive efficacy was...
Compared with the colloidal crystals (CCs) of hard spheres, large-scale, high-quality CCs soft microgel spheres are easier to be assembled because they more tolerant defects. However, assemble CCs, a dispersion should first concentrated and then allowed crystallize, which is tedious time-consuming. Herein, we demonstrated that magnetic poly(N-isopropylacrylamide) (PNIPAM) an Fe3O4 core PNIPAM shell can into quickly by simply applying external field diluted dispersions. The resulting highly...
A cost-effective but simple method for the separation of bovine serum albumin (BSA) from complex biological fluids is still lacking. Here using N-isopropylacrylamide as main monomer and dimethylaminoethyl methacrylate, methacrylic acid, acrylamide functional monomers, a BSA-imprinted polymer was synthesized. To overcome two major obstacles common protein-imprinted polymers, i.e., difficult template removal low imprinting efficiency, an oligo(glutamic acid)-based peptide cross-linker with...
Abstract The lattice Boltzmann method (LBM) is becoming an effective numerical technique of computational fluid dynamics (CFD). In this study, with some new thermal LBM schemes being proposed, the used to simulate gravity current prior backdraft (a particular and hazardous phenomenon in compartment fire) within laminar restrictions. dimensionless time for traveling from opening rear wall a bench‐scale calculated under different geometries, respectively, including: full end opening,...
Abstract A novel and simple “water‐salt‐in‐deep eutectic solvent” (WS‐DES) strategy is reported here to increase the ionic conductivity, while reducing viscosity freezing temperature of deep solvent (DES). Upon addition water strong electrolyte salt DES [LiTFSI][EG], conductivity was increased by 16 times, decreased 36 %, 30 °C. Additionally, WS‐DES can be well applied electrolytes for supercapacitor devices. Compared initial DES, supercapacitors using have higher specific capacitance,...
The wearable devices use piezoelectric power generation technology to collect the energy generated by human motion. Using new material PVDF (polyvinylidene fluoride), oscillator is prepared according structural characteristics of film, and then based on PVDV film fixed physical device complete production module that collects motion energy. By testing module, output data can be obtained used as basis for design each sub-module, hardware circuit autonomous supply system designed accordingly....