A5035677227- Phytochemicals and Antioxidant Activities
- Food composition and properties
- Plant biochemistry and biosynthesis
- Essential Oils and Antimicrobial Activity
- Microbial Metabolites in Food Biotechnology
- Edible Oils Quality and Analysis
- Proteins in Food Systems
- Fermentation and Sensory Analysis
- Genetic and Environmental Crop Studies
- Metabolomics and Mass Spectrometry Studies
- Food Industry and Aquatic Biology
- Plant Gene Expression Analysis
- Antioxidant Activity and Oxidative Stress
- Phytase and its Applications
- Botanical Research and Applications
- Flavonoids in Medical Research
- Biochemical and biochemical processes
- Tea Polyphenols and Effects
- Cynara cardunculus studies
- Phytoestrogen effects and research
- Biofuel production and bioconversion
- Nuts composition and effects
- Plant pathogens and resistance mechanisms
- Spectroscopy and Chemometric Analyses
- Bioactive Compounds in Plants
University of Lisbon
2016-2025
Universidade Nova de Lisboa
2016-2022
Instituto Politécnico de Lisboa
2020-2021
Instituto de Biologia Experimental e Tecnológica
2017-2021
Iscte – Instituto Universitário de Lisboa
2021
Faculdade Meridional
2021
Armada (Poland)
2020
University of Beira Interior
2006
The consumption of chia seeds products has increased recently and it been suggested that the inclusion this functional food in a daily human diet could contribute to improve consumers' health. However, better knowledge about composition these is mandatory. In work, phenolic compounds from commercial samples seed, fiber flour oil were extracted using an ultrasound-assisted methodology separated identified by high-performance liquid chromatography coupled mass spectrometer. Methanol:water...
Salicornia ramosissima J. Woods is a halophyte plant recognized as promising natural ingredient and will eventually be salt substitute (NaCl). However, its shelf-life applicability in several food matrices requires the use of drying processes, which may have an impact on nutritional functional value. The objective this study was to evaluate effect oven freeze-drying processes composition, volatile profile, phytochemical content, bioactivity S. using analytical tools (LC-DAD-ESI-MS/MS...
Polymethoxylated flavones (PMFs) from citrus fruits are reported to present anticancer potential. However, there is a lack of information regarding their effect on cancer stem cell (CSC) populations, which has been recognized as responsible for tumor initiation, relapse, and chemoresistance. In this study, we evaluated the an orange peel extract (OPE) its main PMFs, namely, nobiletin, sinensetin, tangeretin, scutellarein tetramethylether in targeting proliferation stemness using 3D model...
Olive pomace (OP) is the main by-product of olive oil industry produced in large quantities. Its valorization as a source phenolic bioactive compounds paramount for sustainable growth related industries. This work proposes an intensified process to maximize recovery dry extracts using hydroalcoholic mixtures. Supercritical carbon dioxide defatting pre-treatment was performed. Following this, pressurized liquid extraction optimized through circumscribed central composite design. The factors...
Background: Nonunion bone fractures cause chronic pain and disability, posing a significant burden on healthcare systems. Extracorporeal Shockwave Therapy (ESWT) has emerged as promising non-invasive treatment, with studies showing healing success rates between 50% 100%. Methods: This study aims to evaluate the efficacy of focal ESWT (fESWT) in improving consolidation, pain, functionality patients nonunion fractures, identify potential predictive factors treatment rate. Inclusion criteria...
Rice bran (RB) is a rice processing by-product recognized to be source of bioactive compounds, including γ-oryzanol and fatty acids, which have interesting bioactivities such as antioxidant anti-inflammatory effects. This study aims optimize the supercritical fluid extraction process for recovering these high-value compounds from with improved bioactivity. A Central Composite Face-Centered Design was employed by varying temperature (40–80 °C) pressure (200–500 bar). The optimal conditions...
A few studies have investigated the influence on physicochemical and phytochemical compositions during storage in bottle of wine spirits (WS) aged using Alternative Ageing Technology (AAT) compared it to Traditional Technolo-gy (TAT). The aim this study was evaluate effect over one four years evolution chromatic characteristics (CIELab method) (alcoholic strength, acidity total dry ex-tract), phenolic index (TPI), low molecular weight compound contents (HPLC-DAD technique), antioxidant...
Broad-spectrum fluoroquinolone antibiotics (ciprofloxacin and levofloxacin), carbapenem resistance genes, as well viral genomes, were detected in grab samples of wastewater effluents. Passive samplers, which are simpler easier to use provide information about the concentrations combination contaminants present a certain fluid matrix over time, proved be extremely promising devices monitor presence target Nanofiltration was tested with pilot-scale unit installed at domestic treatment...
Although anticancer drugs occur in the aquatic environment at trace concentration levels, these might be of environmental concern due to their potent mechanism action. Hence, new treatment technologies should explored and, if necessary, conventional wastewater plants (WWTPs) upgraded avoid release into environment. The effectiveness nanofiltration remove six from effluents was assessed by installing a pilot unit with Desal 5DK membrane domestic WWTP. Of target drugs, only capecitabine,...
The use of halophyte plants appears as a potential solution for degraded soil, food safety, freshwater scarcity, and coastal area utilization. These have been considered an alternative crop soilless agriculture sustainable natural resources. There are few studies carried out with cultivated halophytes using cultivation system (SCS) that report their nutraceutical value, well benefits on human health. objective this study was to evaluate correlate the nutritional composition, volatile...
Polymethoxylated flavones (PMFs) have been recognized to inhibit colorectal cancer proliferation through various mechanisms, however most of these studies performed on cells grown as monolayers that present limitations in mimicking the 3D tumor architecture and microenvironment. The main aim this study was investigate anticancer potential an orange peel extract (OPE) enriched PMFs a cell model cancer. OPE developed by supercritical fluid extraction effect evaluated HT29 spheroids cultures...
Prediction of retention times (RTs) is increasingly considered in untargeted metabolomics to complement MS/MS matching for annotation unidentified peaks. We tested the performance PredRet (http://predret.org/) predict RTs plant food bioactive metabolites a data sharing initiative containing entry sets 29-103 compounds (totalling 467 compounds, >30 families) across 24 chromatographic systems (CSs). Between 27 and 667 predictions were obtained with median prediction error 0.03-0.76 min...
Bioactive compounds present in plant-based foods, and their metabolites derived from gut microbiota endogenous metabolism, represent thousands of chemical structures potential interest for human nutrition health. State-of-the-art analytical methodologies, including untargeted metabolomics based on high-resolution mass spectrometry, are required the profiling these complex matrices, plant food materials biofluids. The aim this project was to compare coverage methods independently developed...
Antiproliferative and cytotoxic activities of phenolic content from Nerium oleander leaves.
Maize is one of the most interesting dietary sources hydroxycinnamic acids, widely known for their beneficial health effects, namely antioxidant properties. This work aims to identify acids and derivatives in broa, a Portuguese traditional ethnic maize bread, corresponding flours. Soluble insoluble phenolic fractions diverse flours broas were prepared analysed by HPLC-DAD-MS/MS (high-performance liquid chromatography coupled with diode array detector tandem mass spectrometry). Besides free...
Arabinoxylan has prebiotic properties, as it is able to resist digestion in the small intestine and undergoes fermentation large intestine. In this work, arabinoxylan was extracted from corn fiber using an alkaline solution further purified with membrane processing. It found that extracts were mainly composed of xylose (50-52%), arabinose (37-39%), galactose (9%) glucose (1-4%), A/X ratio 0.72-0.77. All phenolic compounds, including ferulic acid derivatives such dimers, trimers tetramers....