A5060515402- Fibromyalgia and Chronic Fatigue Syndrome Research
- Psychosomatic Disorders and Their Treatments
- Musculoskeletal pain and rehabilitation
- Health, psychology, and well-being
- Long-Term Effects of COVID-19
- Genetic Neurodegenerative Diseases
- Analytical Chemistry and Chromatography
- Myofascial pain diagnosis and treatment
- Effects of Vibration on Health
- Eating Disorders and Behaviors
- COVID-19 and Mental Health
- Human Health and Disease
- Psychology, Coaching, and Therapy
- Spaceflight effects on biology
- bioluminescence and chemiluminescence research
- Radiopharmaceutical Chemistry and Applications
- Reliability and Maintenance Optimization
- Child Nutrition and Feeding Issues
- Multiple Sclerosis Research Studies
- biodegradable polymer synthesis and properties
- Corporate Management and Leadership
- Advanced Polymer Synthesis and Characterization
- Advanced Physical and Chemical Molecular Interactions
- T-cell and B-cell Immunology
- Biopolymer Synthesis and Applications
Washington Center
2006-2024
Duke University
2013
Vrije Universiteit Brussel
2007
Duke Medical Center
1997-2006
American Academy of Pediatrics
2006
The Hunterian
2006
Duke University Hospital
1997
Brigham and Women's Hospital
1995
Laboratoire de Chimie Physique
1977-1978
Centre de Recherches sur les Macromolécules Végétales
1958-1965
Techniques of data mining and machine learning were applied to a large database medical facility claims from commercially insured patients determine the prevalence, gender demographics, costs for individuals with provider-assigned diagnosis codes myalgic encephalomyelitis (ME) or chronic fatigue syndrome (CFS). The frequency was 519 – 1,038/100,000 relative risk females being diagnosed ME CFS compared males 1.238 1.178, respectively. While percentage women ME/CFS is higher than men, not...
For a diagnosis of chronic fatigue syndrome (CFS), most researchers use criteria that were developed by Fukuda et al. (1994), with modifications suggested Reeves (2003). However, this case definition was established for adults rather than children. A Canadian Case Definition (ME/CFS; Myalgic Encephalomyelitis/CFS) has recently been developed, more specific inclusion (Carruthers al., 2003). Again, the primary aim is to diagnose adult CFS. significant problem in literature lack both pediatric...
Background Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a severely debilitating disease of unknown pathogenesis consisting variety symptoms including severe fatigue. The objective the study was to examine efficacy and safety TLR-3 agonist, rintatolimod (Poly I: C12U), in patients with CFS/ME. Methods Findings A Phase III prospective, double-blind, randomized, placebo-controlled trial comparing twice weekly IV versus placebo conducted 234 subjects long-standing, CFS/ME at 12...
Mycoplasma fermentans and other species are colonizers of human mucosal surfaces may be associated with immunodeficiency virus infection. While many infectious agents have been described in different percentages patients Chronic Fatigue Syndrome (CFS), little is known about the prevalence mycoplasmas especially M. CFS patients. A polymerase chain reaction (PCR)-based assay was used to detect genus genomes peripheral blood mononuclear cells (PBMC) Blood collected from 100 50 control subjects....
Chronic fatigue syndrome (CFS) is a complex and serious illness that often misunderstood. Experts have noted the terminology "chronic syndrome" can trivialize this stigmatize persons who experience its symptoms (1). The name was coined by group of clinicians convened CDC in late 1980s to develop research case definition for illness, which, at time, called chronic Epstein-Barr virus syndrome. CFS suggested because characteristic persistent experienced all those affected evidence acute or...
In the Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM), we relied on expert clinician diagnoses to enroll patients from 7 specialty clinics in United States order perform a systematic collection data measures myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS). Healthy persons and those with other illnesses that share some features ME/CFS were enrolled comparison groups. The major objectives to: 1) use standardized questionnaires measure...
Chronic overlapping pain conditions (COPCs), pain-related that frequently occur together, may in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and could impact illness severity. This study aimed to identify comorbid COPCs ME/CFS evaluate their on
Abstract. Vojdani A, Ghoneum M, Choppa PC, Magtoto L, Lapp CW (Immunosciences Laboratory Inc., Beverly Hills, and Charles Drew University School of Medicine Science, Los Angeles, California, the Hunter‐Hopkins Centre, Charlotte, North Carolina, USA). Elevated apoptotic cell population in patients with chronic fatigue syn‐drome: pivotal role protein kinase RNA. J Intern Med 1997; 242: 465478. Objectives: A prominent feature syndrome (CFS) is a disordered immune system. Recent evidence...
Overlapping symptomatologies between Chronic Fatigue Syndrome (CFS) and Chemical Sensitivity have been observed by different investigators. Therefore, it is of great importance to develop biomarker(s) for possible differentiation viral induced CFS (without sensitivity chemicals) versus chemically CFS. Since interferon proteins 2-5A Synthetase Protein Kinase RNA (PKR) implicated in the induction CFS, objective this study was utilize PKR activity either viruses or chemicals. Based on CDC...
In 2009, a retrospective study reported the detection of xenotropic murine leukemia virus-related virus (XMRV) in clinical isolates derived from individuals with chronic fatigue syndrome or myalgic encephalomyelitis (CFS). While many efforts to confirm this observation failed, one report detected polytropic (pMLV), instead XMRV. both studies, Polymerase Chain Reaction (PCR)-based methods were employed which could provide basis for development practical diagnostic tool. To these we...
One of the goals Multi-site Clinical Assessment Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM) study was to evaluate whether clinicians experienced in diagnosing and caring for patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) recognized same clinical entity.
Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) experience cognitive problems attention, information processing speed, working memory, learning efficiency, and executive function. Commonly, patients report worsening of symptoms over time after physical and/or challenges. To determine, monitor, manage longitudinal decrements in function such exposures, it is important to be able screen for dysfunction changes clinic also remotely at home. The primary objectives this...
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multisystem illness characterized by substantial reduction in function accompanied profound unexplained not significantly relieved rest, post-exertional malaise, and other symptoms. Reduced natural killer (NK) cell count cytotoxicity has been investigated as biomarker for ME/CFS, but few clinical laboratories offer the test multi-site verification studies have conducted.We determined NK counts 174 (65%) 86 (32%) healthy control...