A5019456070- HIV/AIDS Research and Interventions
- Maternal Mental Health During Pregnancy and Postpartum
- Breastfeeding Practices and Influences
- Cerebrospinal fluid and hydrocephalus
- Family and Disability Support Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Bacterial Infections and Vaccines
- Child and Adolescent Psychosocial and Emotional Development
- HIV-related health complications and treatments
- Nosocomial Infections in ICU
- Childhood Cancer Survivors' Quality of Life
- Neonatal and Maternal Infections
- Traumatic Brain Injury and Neurovascular Disturbances
- Psychosomatic Disorders and Their Treatments
- Autism Spectrum Disorder Research
- Maternal and Perinatal Health Interventions
- Infant Development and Preterm Care
- Adolescent and Pediatric Healthcare
- Assisted Reproductive Technology and Twin Pregnancy
- Genomics and Rare Diseases
- Infection Control in Healthcare
- HIV, Drug Use, Sexual Risk
- COVID-19 epidemiological studies
- Vagus Nerve Stimulation Research
- Gastric Cancer Management and Outcomes
McMaster University
2016-2025
Michigan State University
2025
Hamilton Health Sciences
2019-2025
University of Karachi
2023
McMaster Children's Hospital
2022-2023
Pakistan Institute of Medical Sciences
2023
Mount Sinai Beth Israel
2023
University of Management and Technology
2023
Icahn School of Medicine at Mount Sinai
2019-2022
University of Arkansas for Medical Sciences
2022
Depressive disorders are common and disabling among perinatal women. The rates high in ethnic minority groups. causes not known British Pakistani aim of this study was to estimate the rates, correlates maintaining factors depression a sample UK. design used cross-sectional two phase population based survey with prospective cohort study.All women 3rd trimester attending antenatal clinic were screened Edinburgh postnatal scale (EPDS). Women scoring 12 or more on EPDS random low scorers...
Abstract Background As per IDSA guidelines, throat swab testing for group A Streptococcus is important to ensure appropriate antimicrobial use children with pharyngitis that not obviously viral. Bacterial culture the diagnostic reference standard but takes days result. With culture, physicians often initially provide a prescription only be filled later on if GAS positive. Unfortunately, this strategy can result in inappropriate treatment parents of negative tests fill script anyway, or...
Abstract Observers were randomized to time and location across two different Neonatal Intensive Care Units (NICUs) count hand hygiene opportunities (HHOs). Mean hourly HHO was lower at night during use of precautions, higher in shared rooms. benchmarks can support implementation group electronic monitoring systems NICUs.
Orthostatic intolerance-OI is common in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-ME/CFS. We used a 10-min passive vertical lean test as orthostatic challenge-OC and measured changes vitals end tidal CO
The reduction in human immunodeficiency virus (HIV) transmission through breastmilk with maternal combination antiretroviral therapy (cART) has led many pregnant women living HIV and healthcare providers to question exclusive formula feeding resource-rich settings. Here, we describe cART prophylaxis 3 breastfed infants whose mothers had sustained virologic suppression; all of these remained uninfected.
Chronic overlapping pain conditions (COPCs), pain-related that frequently occur together, may in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and could impact illness severity. This study aimed to identify comorbid COPCs ME/CFS evaluate their on
Perinatal depression has been found to be a strong and independent risk factor for poor child growth development in low-income South Asian populations. The authors aimed study if there was similar association first second-generation British women of Pakistani origin.A prospective cohort study.The conducted the North-West England, areas with high density Pakistani-origin population. subjects were recruited from Central Manchester Hospital City East Lancashire Lancashire.704 physically healthy...
Background: Breastfeeding is not recommended for women living with HIV (WLWH) in Canada. We described the prevalence of breastfeeding and explored experiences care, support, stigma related to infant feeding. Setting: Quebec, Ontario, British Columbia (Canada). Methods: Data were obtained from Women's Sexual Reproductive Health Cohort Study (CHIWOS) surveys, conducted between 2013 2018. Results: was reported by 73.5% 786 who delivered before diagnosis 7.3% 289 after diagnosis. Among them,...
Objective: To determine if presence of co-existing medically unexplained syndromes or psychiatric diagnoses affect symptom frequency, severity activity impairment in Chronic Fatigue Syndrome.Patients: Sequential Syndrome patients presenting one clinical practice.Design: Participants underwent a diagnostic interview and were evaluated for fibromyalgia, irritable bowel syndrome and/or multiple chemical sensitivity.Main Measures: Structured Clinical Interview [SCID] DSM-IV; SF-36,...
The HIV Mothering Study (n = 72) was a prospective, observational, cohort study exploring psychosocial experiences and needs of WLWHIV in pregnancy postpartum. We performed quantitative analysis determinants loneliness (UCLA Loneliness Scale) lower perceived social support (SS) (Medical Outcomes Study-Social Support Survey). hypothesized included: age, years with HIV, racism (Everyday Discrimination Scale), depression (Edinburgh Postnatal Depression Scale [EPDS]), nadir CD4 (<200 cells/μL),...
Abstract Background Suicide is a major public health problem worldwide. In the UK suicide second most common cause of death in people aged 15-24 years. Self harm one commonest reasons for medical admission UK. year following attempt risk repeat or by may be up to 100 times greater than who have never attempted suicide. Research evidence shows increased and among British South Asian women. There are concerns about current service provision its appropriateness this community due low numbers...
Background: The historical focus on autism as a childhood disorder means that evidence regarding in adulthood lags significantly behind research other age groups. Emerging studies the relationship of with characteristics do not target older adult samples, which presents barrier to studying important variability exists life span developmental research. This study aims further our understanding between Autism-Spectrum Quotient Scale and large sample. Methods: present examines (AQ) scores 1139...
Late-onset infections (LOI) are a major cause of morbidity and mortality among patients in the neonatal intensive care unit (NICU). Gloving after hand hygiene may be pragmatic approach to prevent that arise when healthcare workers' hands transmit pathogens neonates.To determine feasibility conducting multicenter, open-labeled randomized controlled trial (RCT) whether protocol requires workers (HCWs) level 3 NICU wear non-sterile gloves plus reduces occurrence late-onset infection, compared...
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multisystem illness characterized by substantial reduction in function accompanied profound unexplained not significantly relieved rest, post-exertional malaise, and other symptoms. Reduced natural killer (NK) cell count cytotoxicity has been investigated as biomarker for ME/CFS, but few clinical laboratories offer the test multi-site verification studies have conducted.We determined NK counts 174 (65%) 86 (32%) healthy control...
Genomic epidemiology can facilitate an understanding of evolutionary history and transmission dynamics a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak. We used next-generation sequencing techniques to study SARS-CoV-2 genomes isolated from patients health care workers (HCWs) across five wards Canadian hospital with ongoing Using traditional contact tracing methods, we show events between HCWs, which were also supported by the lineage assignments. The outbreak...
Infections complicate 5%-10% of cerebrospinal fluid (CSF) shunts. We aimed to describe the characteristics and contemporary pathogens shunt infections in children Canada United States.Descriptive case series at tertiary care hospitals (N = 8) States 3) up 18 years age with CSF from July 1, 2013, through June 30, 2019.There were 154 (43% female, median 2.7 years, 50% premature) ≥1 infections. Median time between placement infection was 54 days (interquartile range, 24 days-2.3 years). Common...
Khan, Sarah MD, MSc; Kennedy, Victoria Logan RN, MN; Loutfy, Mona MPH; MacGillivray, Jay RM; Yudin, Mark Read, Stanley MSc, PhD; Bitnun, Ari MSc Author Information
Providing comprehensive infant feeding guidance to families affected by HIV is complex and requires a multidisciplinary approach. While exclusive formula remains the preferred recommendation for infants born women living with (WLWH) in high-income countries, more nuanced approach that may include option of breastfeeding under certain circumstances emerging many resource-rich countries.The Canadian Pediatric & Perinatal HIV/AIDS Research Group (CPARG) hosted Institute Health Research-funded...
OBJECTIVE Cerebrospinal fluid (CSF) white blood cell (WBC) count, neutrophil percentage, protein concentration, and glucose level are typically measured at diagnosis serially during the treatment of CSF shunt infections. The objective this retrospective cohort study was to describe longitudinal profile parameters in children with infections assess their association outcome. METHODS Participants were treated 11 tertiary pediatric hospitals Canada United States for infection, from July 1,...
Chromosome 1 is the largest of all human chromosomes, containing 3141 genes. It linked to 890 known genetic diseases including congenital hypothyroidism, hemochromatosis, and prostate cancer. Recognized deletion duplication syndromes have been described. Deletions in short arm (p) chromosome identified tumors brain kidneys. Duplications long (q) are reported myelodysplastic syndromes. Solitary 1p36 or 1q42 rarely entities their associations with malignancy not characterized. We report a case...