A5052022000- Parasitic Diseases Research and Treatment
- Parasite Biology and Host Interactions
- Parasites and Host Interactions
- Mosquito-borne diseases and control
- Zoonotic diseases and public health
- Insect symbiosis and bacterial influences
- Malaria Research and Control
- Global Maternal and Child Health
- Insects and Parasite Interactions
- Circadian rhythm and melatonin
- Workplace Health and Well-being
- Sleep and related disorders
- Physical Activity and Health
- Healthcare professionals’ stress and burnout
- Health, psychology, and well-being
- Sleep and Work-Related Fatigue
- Helminth infection and control
- Childhood Cancer Survivors' Quality of Life
- Cancer survivorship and care
Family Health International 360
2021-2022
The Task Force for Global Health
2017-2020
Lancaster University
2020
Health Data Research UK
2020
United States Agency for International Development
2020
Centerforce
2010
University of South Carolina
2007-2009
Background Shiftwork among health care workers impacts upon the safety and of both employees patients.
Circadian disruption has been linked with inflammation, an established cancer risk factor. Per3 clock gene polymorphisms have also associated circadian and increased risk. Patients completed a questionnaire provided blood sample prior to undergoing colonoscopy (n = 70). Adjusted mean serum cytokine concentrations (IL-6, TNF-alpha, gamma-INF, IL-1ra, IL-1-beta, VEGF) were compared among patients high low scores for fatigue (Multidimensional Fatigue Inventory), depressive symptoms (Beck...
The meaning of 'mapping' in relation to onchocerciasis has changed at least three times over the past 50 years as programmatic goals and assessment tools have changed. With current goal being global elimination Onchocerca volvulus (OV), all areas where OV might currently be transmitted mass drug administration (MDA) with ivermectin treatment not been delivered previously must now identified by careful, detailed 'elimination mapping' either endemic or not, so that appropriate targets can...
BackgroundThe Mectizan Donation Program (MDP) was established in 1987 to oversee Merck's donation of (ivermectin, MSD) for the control onchocerciasis (river
Studies in Sub Saharan Africa have shown that the Circulating Cathodic Antigen point-of-care-test (POC-CCA) is more accurate detections of S. mansoni than microscopic Kato-Katz technique but less known about accuracy this rapid test detecting haematobium infections. This study was intended to evaluate field POC-CCA as a kit for schistosomiasis mapping The Gambia.
Background Exercise has been shown to decrease breast cancer risk and slow the progression of cancer. Physician recommendations clinical research data most often are for gym-based exercise programs. However, importance location on mood stress hormones that may influence adherence not addressed. Methods Women first walked an hour outdoors along a university path then week later, indoors treadmill in typical gym environment. Pre post outdoor indoor moods (happy, pleased, sad, frustrated,...
Background The goal of the global lymphatic filariasis (LF) program is to eliminate disease as a public health problem by year 2020. WHO mapping protocol that used identify endemic areas in need mass drug administration (MDA) uses convenience-based sampling. This rapid has allowed dramatically scale up treatment, but approaches its elimination goal, it important ensure all have been identified and received MDA. In low transmission settings, for LF several limitations. To correctly endemicity...
Countries across West Africa began reporting COVID-19 cases in February 2020. By March, the pandemic disrupting activities to control and eliminate neglected tropical diseases (NTDs) as health ministries ramped up COVID-19-related policies prevention measures. This was followed by interim guidance from WHO April 2020 temporarily pause mass drug administration (MDA) community-based surveys for NTDs. While quickly evolving worldwide, most of Africa, governments took quick action implement...
The lack of a WHO-recommended strategy for onchocerciasis treatment with ivermectin in hypo-endemic areas co-endemic loiasis is an impediment to global elimination. New diagnostics (LoaScope; Loa antibody rapid test) and risk prediction tools may enable safe mass decisions areas. In 2017-2018, integrated mapping onchocerciasis, lymphatic filariasis (LF), loiasis, aimed at enabling decisions, was piloted Gabon. Three ivermectin-naïve departments suspected be were selected up 100 adults per...
The elimination of onchocerciasis through community-based Mass Drug Administration (MDA) ivermectin (Mectizan) is hampered by co-endemicity Loa loa, as individuals who are highly co-infected with loa parasites can suffer serious and occasionally fatal neurological reactions from the drug. test-and-not-treat strategy testing all participating in MDA has some operational constraints including cost limited availability LoaScope diagnostic tools. As a result, Antibody (Ab) Rapid Test was...
Mapping is a prerequisite for effective implementation of interventions against neglected tropical diseases (NTDs). Before the accelerated World Health Organization (WHO)/Regional Office Africa (AFRO) NTD Project was initiated in 2014, mapping efforts many countries were frequently carried out an ad hoc and nonstandardized fashion. In 2013, there at least 2,200 different districts (of 4,851 WHO African region) that still required mapping, these districts, more than one disease needed to be...
The discovery of Mectizan has engendered a safe onchocerciasis chemoprevention tool. To make the drug available promptly to people at risk onchocerciasis, procurement and delivery mechanism been put in place around Donation Program, which oversees Merck donation Mectizan. number yearly approved treatment doses increased rapidly since 1988 from 255,000 more than 80 million 2007 2008. Cumulatively, 1987 2008 697 have corresponding 1.5 billion tablets shipped. Although current demand for is...
<ns7:p><ns7:bold>Background:</ns7:bold> Monitoring vector-borne diseases requires sampling of very large numbers disease vectors in order to corroborate infections the human population. This can be challenging, as current vector collection tools are either inefficient, or expensive implement from a public health perspective. To circumvent this challenge, study compared community strategy using double-netted mosquito method (a tent trap (TT)) traditional landing (HLC) three communities...
<ns4:p><ns4:bold>Background:</ns4:bold> Monitoring vector-borne diseases requires sampling of very large numbers disease vectors in order to corroborate infections the human population. This can be challenging, as current vector collection tools are either inefficient, or expensive implement from a public health perspective. To circumvent this challenge, study compared community strategy using double-netted mosquito method (a tent trap (TT)) traditional landing (HLC) three communities...
Vector-borne diseases have long presented major challenges to the health of rural communities in wet tropical regions world, but especially sub-Saharan Africa. In this paper, we describe contribution that statistical modelling has made global elimination programme for one vector-borne disease, onchocerciasis. We explain why information on spatial distribution a second Loa loa, is needed before at high risk onchocerciasis can be treated safely with mass ivermectin, an antifiarial medication....