A5078206337- Mosquito-borne diseases and control
- Malaria Research and Control
- Parasitic Diseases Research and Treatment
- Parasite Biology and Host Interactions
- Parasites and Host Interactions
- Viral Infections and Vectors
- Morinda citrifolia extract uses
- Bioactive Compounds and Antitumor Agents
- Insect Pest Control Strategies
- Toxoplasma gondii Research Studies
- Insect symbiosis and bacterial influences
- Insects and Parasite Interactions
- Species Distribution and Climate Change
- Dengue and Mosquito Control Research
- Viral Infections and Outbreaks Research
- Heme Oxygenase-1 and Carbon Monoxide
- Herpesvirus Infections and Treatments
- Phytochemistry and Biological Activities
- Global Health and Surgery
- Natural product bioactivities and synthesis
- Sex work and related issues
- T-cell and Retrovirus Studies
- Biomedical Ethics and Regulation
- Crystallography and molecular interactions
- Pharmacological Effects of Natural Compounds
Noguchi Memorial Institute for Medical Research
2015-2024
University of Ghana
2015-2024
Erasmus MC
2018-2019
Tulane University
1986
Background. Several African countries have adopted a biannual ivermectin distribution strategy in some foci to control and eliminate onchocerciasis. In 2010, the Ghana Health Service started combat transmission hotspots suboptimal responses treatment. We assessed epidemiological impact of first 3 years this quantified over 2 consecutive rounds treatment 10 sentinel communities. Methods. evaluated Onchocerca volvulus community microfilarial intensity prevalence persons aged ≥20 before first,...
Ghana’s lymphatic filariasis (LF) elimination was intensified by Global Programme to Eliminate Lymphatic in 2000. LF transmission interrupted some endemic district, yet, persistent others. This study investigated characteristics of Wuchereria bancrofti that potentially contribute districts after prolonged mass chemotherapy (≧15yrs) expected interrupt transmission. Participants’ finger-prick blood screened for antigenaemia and positives followed night detect microfilariae. The...
Trypanosoma brucei parasites are kinetoplastid protozoa that devastate the health and economic well-being of millions people in Africa through disease human African trypanosomiasis (HAT). New chemotherapy has been eagerly awaited due to severe side effects drug resistance issues plaguing current drugs. Recently, there an emphasis on use medicinal plants worldwide. Morinda lucida Benth. is a popular plant widely distributed Africa, several research groups have reported antiprotozoal...
Abstract Aedes aegypti (L.) (Diptera: Culicidae) is a diurnal feeder that lives in close association with human populations. It the principal vector of yellow fever, dengue fever and Zika Virus. Issues arboviral diseases have been on ascendency most countries including Ghana where mosquito main fever. A comparative study biting behavior Ae. identification subspecies were undertaken using molecular technique. Standard landing technique was used to collect both indoor outdoor mosquitoes at...
High-malaria burden countries in sub-Saharan Africa are shifting from malaria control towards elimination. Hence, there is need to gain a contemporary understanding of how indoor residual spraying (IRS) with non-pyrethroid insecticides when combined long-lasting insecticidal nets (LLINs) impregnated pyrethroid insecticides, contribute the efforts National Malaria Control Programmes interrupt transmission and reduce reservoir Plasmodium falciparum infections across all ages. Using an...
Abstract Vector-borne diseases emergence, particularly malaria, present a significant public health challenge worldwide. Anophelines are predominant malaria vectors, with varied distribution, and influenced by environment climate. This study, in Ghana, modelled environmental suitability for Anopheles stephensi , potential vector that may threaten advances control. Understanding this vector’s distribution dynamics ensures effective control programmes implementation. We explored the MaxEnt...
Mass drug administration (MDA) programmes for the control of lymphatic filariasis in Ghana, have been ongoing some endemic districts 16 years. The current study aimed to assess factors that govern success MDA breaking transmission Ghana. was undertaken two "hotspot" (Ahanta West and Kassena Nankana West) (Mpohor Bongo) Mosquitoes were collected identified using morphological molecular tools. A proportion cibarial armatures each species examined. Dissections performed on Anopheles gambiae...
Ghana started its national programme to eliminate lymphatic filariasis (LF) in 2000, with mass drug administration (MDA) ivermectin and albendazole as main strategy. We review the progress towards elimination that was made by 2016 for all endemic districts of analyze microfilaria (mf) prevalence from sentinel spot-check sites districts.We reviewed district level data on history MDA outcomes transmission assessment surveys (TAS). further collated analyzed mf sites.MDA initiated 2001-2006 98...
Abstract The most widespread arboviral diseases such as Dengue, Chikungunya, and Zika are transmitted mainly by Aedes mosquitoes. Due to the lack of effective therapeutics for these diseases, vector control remains preventative measure. This study investigated compared species composition, insecticide susceptibility, resistance mechanisms in mosquito populations from a forest reserve converted an eco-park peri-domestic sites urban Accra, Ghana. Immature were sampled sites, raised adults,...
Malaria incidence in urban areas has generally been low compared to rural but recent data indicate that malaria remains a public health problem. It is therefore important understand the factors promote help formulate future vector control strategies. This study Anopheles gambiae s.l. (A. s.l.) species composition, distribution and insecticide resistance mechanisms between vegetable non-vegetable growing Accra Metropolis. Four sites were selected within city of which comprised two...
Dengue, Zika and chikungunya are Aedes -borne viral diseases that have become great global health concerns in the past years. Several countries Africa reported outbreaks of these despite Ghana sharing borders with some countries, such yet to be detected. Viral RNA antibodies against dengue serotype-2 recently been among individuals localities regional capital Ghana. This is an indication a possible silent transmission ongoing population. study, therefore, investigated entomological risk...
The development of antibody testing for the diagnosis lymphatic filariasis (LF) is intended to enhance monitoring and evaluation activities Global Program Elimination LF. This due fact that tests are expected be most sensitive at detecting exposure LF compared antigen takes longer develop. To this end a new antibody-based enzyme linked immunosorbent assay (ELISA) Wuchereria bancrofti Wb123 has been developed further designed into point care rapid diagnostic test, under evaluation. In...
Abstract Background Recently, arboviruses have been of concern as pathogens for emerging and re-emerging infectious diseases. In Ghana, yellow fever outbreak occurred in Savannah Region the year 2021. A team from different institutions, organisations, stakeholders health with varying vital expertise was assembled to respond this national emergency assess, contain and/or control rapid spread disease. This paper presents findings entomological investigations conducted during outbreak. Methods...
<ns7:p><ns7:bold>Background:</ns7:bold> Monitoring vector-borne diseases requires sampling of very large numbers disease vectors in order to corroborate infections the human population. This can be challenging, as current vector collection tools are either inefficient, or expensive implement from a public health perspective. To circumvent this challenge, study compared community strategy using double-netted mosquito method (a tent trap (TT)) traditional landing (HLC) three communities...
Aedes-borne diseases remain a public health challenge for many countries globally. The extent of spread invasive species Aedes mosquitoes and risk transmission the especially around point entry goods such as ports is not well known in Ghana. This study investigated ecology, distribution viral haemorrhagic fevers by port areas Tema, Southern from this were collected using human landing catches, ovitraps larval collections period six months. A total 1092 containers inspected both seasons...