Irène Ayi

ORCID: 0000-0003-3054-9494
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About
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Research Areas
  • Parasites and Host Interactions
  • Parasite Biology and Host Interactions
  • Helminth infection and control
  • Child Nutrition and Water Access
  • Parasitic Infections and Diagnostics
  • Toxoplasma gondii Research Studies
  • Malaria Research and Control
  • Research on Leishmaniasis Studies
  • Mosquito-borne diseases and control
  • Trypanosoma species research and implications
  • Amoebic Infections and Treatments
  • Fluorine in Organic Chemistry
  • Herpesvirus Infections and Treatments
  • Morinda citrifolia extract uses
  • Bioactive Compounds and Antitumor Agents
  • Cytomegalovirus and herpesvirus research
  • Iron Metabolism and Disorders
  • Sex work and related issues
  • Moringa oleifera research and applications
  • Zoonotic diseases and public health
  • Synthesis and Reactions of Organic Compounds
  • Global Maternal and Child Health
  • Chemical Synthesis and Analysis
  • Rabies epidemiology and control
  • Heme Oxygenase-1 and Carbon Monoxide

Noguchi Memorial Institute for Medical Research
2015-2024

University of Ghana
2015-2024

University of Bahrain
2010

Tokyo Medical and Dental University
2004

Université Côte d'Azur
1991-1995

Abstract Background School children have been increasingly recognized as health messengers for malaria control. However, little evidence is available. The objective of this study was to determine the impact school-based education intervention on school and community adults. Methods This conducted in Dangme-East district Greater Accra Region, Ghana, between 2007 2008. Trained schoolteachers designed participatory activities led disseminate messages related control their communities. Three...

10.1186/1475-2875-9-98 article EN cc-by Malaria Journal 2010-04-18

To investigate Toxoplasma infection among pregnant women in relation to exposure risk, age and pregnancy-related risk factors.This cross-sectional study involved 294 attending ante-natal clinic Accra who consented participate. Personal related data were obtained by questionnaire interviews. Venous blood was safely drawn from each participant spun obtain sera. Each of the 159 randomly selected serum samples tested for specific anti-Toxoplasma (anti-T. gondii) antibodies IgG, IgA IgM using a...

10.4314/gmj.v43i3.55325 article EN cc-by Deleted Journal 2010-06-08

‘Home-grown’ school feeding programmes are complex interventions with the potential to link increased demand for goods and services community-based stakeholders, including smallholder farmers women’s groups. There is limited rigorous evidence, however, that this case in practice. This evaluation will examine explicitly, from a holistic perspective, simultaneous impact of national meals programme on micronutrient status, alongside outcomes nutrition, education agriculture domains. The 3-year...

10.1186/s13063-015-1116-0 article EN cc-by Trials 2016-01-20

Trypanosomiasis, leishmaniasis, and malaria are protozoan infections of public health importance with thousands new cases recorded annually. Control these infection(s) existing chemotherapy is limited by drug toxicity, lengthy parenteral treatment, affordability, and/or the emergence resistant strains. Medicinal plants on other hand used in treatment various infectious diseases although their chemical properties not fully evaluated. In this study, we screened 112 crude extracts from 72...

10.1002/ptr.6093 article EN Phytotherapy Research 2018-05-07

Trypanosoma brucei parasites are kinetoplastid protozoa that devastate the health and economic well-being of millions people in Africa through disease human African trypanosomiasis (HAT). New chemotherapy has been eagerly awaited due to severe side effects drug resistance issues plaguing current drugs. Recently, there an emphasis on use medicinal plants worldwide. Morinda lucida Benth. is a popular plant widely distributed Africa, several research groups have reported antiprotozoal...

10.1128/aac.01916-15 article EN cc-by Antimicrobial Agents and Chemotherapy 2016-03-08

Anaemia among children is a public health issue in Ghana. The Ghana School Feeding Programme (GSFP) was instituted on pilot basis an effort to provide nutritious lunch school children. Evidence the nutritional status of pupils needed inform expansion GSFP. This study sought assess anaemia Ghanaian pupils.

10.11694/pamj.supp.2014.17.1.3205 article EN PubMed 2014-01-01

Toxoplasma gondii infection can lead to severe disease outcomes in immune-compromised people. This study sought determine the seroprevalence of anti-T. antibodies among pregnant women, hospitalized children (<5 years old) and HIV-seropositive persons Accra. A cross-sectional was conducted two hospitals Accra, a total 450 voluntary participants were recruited for consisting 125 200 persons. Serum obtained from venous blood safely drawn each participant tested specific anti-Toxoplasma IgG IgM...

10.1186/s41182-016-0018-5 article EN cc-by Tropical Medicine and Health 2016-06-01

Food from animal sources continues to be a significant food safety hazard. This study determined the microbial quality and of beef along value chains with case studies in Ashaiman Municipality Ghana. Raw samples were collected four slaughter slabs analyzed using standard microbiological methods determine prevalence specific pathogens, including Salmonella species, Listeria monocytogenes (L. monocytogenes), Brucella as well Toxoplasma gondii (T. gondii), Cyclospora cayetanensis (C....

10.3389/fvets.2022.813422 article EN cc-by Frontiers in Veterinary Science 2022-06-22

Abstract Background In 2005, Ghana replaced chloroquine with artemisinin-based combination therapy as the first-line treatment for uncomplicated malaria. The aim of this work was to determine first time, polymorphisms in putative pfATPase6 and pftctp , pfmdr1 pfcrt genes Ghanaian isolates, particularly at a time when there is no report on artemisinin resistance malaria parasites from Ghana. sensitivity parasite isolates anti-malaria drugs were also evaluated possible association these genes....

10.1186/1475-2875-10-187 article EN cc-by Malaria Journal 2011-07-11

Cryptosporidium is a protozoan parasite which can be transmitted via food and water. Some studies have shown irrigation water to routes of transmission for into the chain, however, little information known about levels in wastewater used Kumasi Metropolis Ghana. that matter Ghana not immune widespread practice farm produce developing countries has attracted attention both, policy makers academia. However, most previous microbial risk assessment focus on possible health effects estimation...

10.1016/j.mran.2017.06.001 article EN cc-by Microbial Risk Analysis 2017-06-30

African Trypanosomiasis caused by trypanosome parasites continues to be a major neglected health problem, particularly in developing countries. Current treatments are marked serious side effects, low effectiveness, high toxicity, and drug resistance prompting the need develop novel, safe, effective, alternative antitrypanosomal compounds.

10.1016/j.heliyon.2024.e28025 article EN cc-by-nc Heliyon 2024-03-01

is a leading cause of severe diarrhea and mortality in young children infants Africa southern Asia. More than twenty

10.1101/2024.04.17.589752 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-04-18

About 20-90% of the world's population has had contact with Toxoplasma gondii parasites. The aim this study was to determine seroprevalence and risk factors associated T. infection in Central Region, Ghana. A community-based cross-sectional conducted three selected communities. Serum samples were tested for presence anti-T. IgG IgM antibodies by ELISA. serological criterion seropositivity a positive test result any two anti-Toxoplasma or combination both. In all, 390 participants mean age...

10.1017/s0950268814002957 article EN Epidemiology and Infection 2014-11-06

To conduct the first ever population-based survey on ocular toxoplasmosis in Central Region of Ghana.A cross-sectional study was conducted three randomly selected communities Region, Ghana. Visual acuity (VA) measurement, dilated fundus examination by indirect ophthalmoscopy and serology testing were performed all participants. Ocular diagnosed based characteristic retinal lesions supported positive serologic using commercial enzyme-linked immunosorbent assay (ELISA) kits.A total 390...

10.3109/09286586.2015.1089579 article EN Ophthalmic Epidemiology 2016-01-02

The study determined the seroprevalence of Toxocara canis infection among children attending four selected health facilities in Central Region Ghana.Cross-sectional study.Sera from 566 aged 1-15 years Ghana between July and September 2012 was used a excretory-secretory antigen-based ELISA to detect serum IgG. A short questionnaire designed obtain data on respondents as age, gender, educational level, locality residence, habits washing fruits, vegetable hands before eating, keeping pet (dogs...

10.4314/gmj.v49i2.3 article EN cc-by Deleted Journal 2015-08-03

Introduction: Anaemia among children is a public health issue in Ghana. The Ghana School Feeding Programme (GSFP) was instituted on pilot basis an effort to provide nutritious lunch school children. Evidence the nutritional status of pupils needed inform expansion GSFP. This study sought assess anaemia Ghanaian pupils.

10.11604/pamjs.supp.2014.17.1.3205 article EN cc-by Pan African Medical Journal 2014-01-01

Background In tropical settings, malaria education at school is potentially useful, but textbook content related to has so far received little attention. This study aimed examine whether textbooks contain sufficient knowledge and skills help children in primary lower secondary schools their family members cope with malaria. Methodology/Principal Findings was a descriptive, cross-country study. We collected that were used by grades one nine from countries endemic for malaria: Laos, Cambodia,...

10.1371/journal.pone.0036629 article EN cc-by PLoS ONE 2012-05-04

Understanding contextual risk factors for haemoglobin (Hb) status and anaemia of rural school-aged children (SAC) adolescents is critical in developing appropriate interventions to prevent anaemia. We analysed secondary data from the baseline an impact evaluation Ghana School Feeding Programme determine severity associated with Hb among SAC (6-9 years; n = 323) (10-17 319) Ghana. used regression models variable selection based on backward elimination our analyses. The mean was 113.8 ± 13.1...

10.1111/mcn.12643 article EN cc-by Maternal and Child Nutrition 2018-07-25
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