A5043667408- Phytochemicals and Antioxidant Activities
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Phytochemistry and Biological Activities
- Gastric Cancer Management and Outcomes
- Essential Oils and Antimicrobial Activity
- Inflammatory Biomarkers in Disease Prognosis
- Metastasis and carcinoma case studies
- Gastroesophageal reflux and treatments
- Temporomandibular Joint Disorders
- Studies on Chitinases and Chitosanases
- Medicinal Plant Research
- Fungal Biology and Applications
- Eosinophilic Esophagitis
- Diabetes and associated disorders
- Refrigeration and Air Conditioning Technologies
- Cancer Genomics and Diagnostics
- Bone Tumor Diagnosis and Treatments
- Gastrointestinal Tumor Research and Treatment
- Circular RNAs in diseases
- Esophageal and GI Pathology
- Pancreatic and Hepatic Oncology Research
- Oral and Maxillofacial Pathology
- Helicobacter pylori-related gastroenterology studies
- Galectins and Cancer Biology
- Peptidase Inhibition and Analysis
Iuliu Hațieganu University of Medicine and Pharmacy
2023-2025
Institutul Regional de Gastroenterologie Prof. Dr. Octavian Fodor
2022-2025
Background: Gastric cancer remains a leading global health challenge, despite advances in surgical techniques and perioperative care. Patients with gastric present degree of postoperative complications, most notably anastomotic fistulas, which can lead to high level morbidity mortality. Although significant have been made their management by implementing less invasive methods, issues debate remain regarding early detection treatment decisions. The purpose this study was emphasize the...
Nutraceuticals represent an emerging and dynamic scientific field due to their important potential in integrated healthcare through nutritional medicinal approaches that interact complement each other mutually. In attempt find new sources for such preparations, the present research focuses on species
(1) Objectives: Assessment of novel impedance parameters such as the post-reflux swallow-induced peristaltic wave (PSPW) index and mean nocturnal baseline (MNBI) have been proposed to enhance accuracy gastroesophageal reflux disease (GERD) diagnosis. We aimed evaluate clinical value MNBI PSPW in discerning different phenotypes GERD children. (2) Methods: conducted a prospective, observational study that included 49 children aged 5-18 years, referred for MII-pH monitoring due negative...
Nowadays, there is an increasing interest in the study of medicinal and aromatic plants, due to their therapeutic properties that correlate with presence different active compounds. Agastache species (sp.) are plants belong Lamiaceae family, originating from North America East Asia. The present aimed evaluate composition essential oils (EOs) obtained Romanian cultivated sp. investigate antibacterial cytotoxic activities. gas chromatography-mass spectrometry (GC–MS) screening revealed...
Gallstones are a common surgical pathology. Laparoscopic cholecystectomy represents the elective treatment. Complicated cases can increase rate of conversion, duration, and difficulty intervention, along with hospitalization period. A prospective cohort study was conducted on 51 patients gallstones. Only subjects normal renal, pancreatic, hepatic functions were included. The severity cholecystitis evaluated by considering ultrasound examination, intraoperative findings, pathology report. We...
Gastric cancer is the fifth type of neoplasia most frequently diagnosed and fourth cause death among other cancers. Prevalence around two times higher for males than females. Chitotriosidase neopterin are molecular biomarkers with potential diagnostic prognostic use in malignant pathology. We conducted a longitudinal prospective cohort study on thirty-nine patients gastric adenocarcinoma, male-to-female ratio 1.78 an average age 64.3 ± 9.97 years. No statistically significant differences...
Background and aims. Hashimoto’s thyroiditis (HT) is an autoimmune disorder that can lead to hypothyroidism. The pathophysiology of HT involves the production antithyroid antibodies attack thyroid tissue, causing inflammation progressive fibrosis. Recent studies demonstrated a strong correlation between Interleukin-2 (IL-2) levels development diseases, suggesting this cytokine may play crucial role in pathogenesis HT. Methods. In study, we determined presence point mutation +114T/G IL-2 gene...
Pancreatic Ductal Adenocarcinoma (PDAC) is a pathology with very poor prognostic, the only curative treatment option being surgery, in association chemotherapy. This study aims to assess influence that use of standardized report after pancreaticoduodenectomy (PD) has on R1 margins rate and impact this long term survival. Material
(1) Background: Multichannel intraluminal impedance-pH (MII-pH) monitoring is commonly used to diagnose gastroesophageal reflux disease (GERD). The mean nocturnal baseline impedance (MNBI) an important parameter, reflecting the esophageal mucosal integrity and improvement in GERD. This study aims evaluate correlation between conventionally measured MNBI a recently described simple measurement method diagnosing pediatric (2) Methods: prospective observational enrolled 64 children aged one...
: Cholangiocarcinoma (CCA) is a highly aggressive cancer of the bile ducts with poor prognosis and limited diagnostic markers. This study aims to investigate potential miR-18a miR-532 as biomarkers for CCA by exploring their correlations clinical parameters traditional tumor markers such CA19.9, CEA, AFP.
: The main aim of this research was to assess the reliability two systems designed specifically for condylar movement recording using slope and Bennett angle information. objectives were evaluate validity subsequent null hypotheses: (1) there is no significant difference between measurements taken at T0 (initial) T1 (after one week) same equipment; (2) notable in values obtained Modjaw Cadiax 2.
The purpose of the study was to assess relationship between inflammatory biomarkers (NLR-neutrophil-to-lymphocyte ratio, PLR-platelet-to-lymphocyte LMR-lymphocyte-to-monocyte SII-systemic immune-inflammation index) and overall survival in gastric cancer patients.Over a six-year period (2016-2021), we conducted longitudinal retrospective cohort research on 549 patients with resectable stomach adenocarcinoma. determined using univariate multivariate COX proportional hazards models.The age...
Background and Objectives: The aim was to evaluate the association of inflammatory biomarkers with resectability overall survival in hilar cholangiocarcinoma. Materials Methods: We conducted a retrospective cohort study over 72 consecutive surgical cases Klatskin tumor an 11-year period. sample divided into two groups: 42 resection 30 unresectable tumors. Values ratios were compared according resectability. Log-rank test, univariate, multivariate Cox proportional hazards models used...
This study aimed to provide a complex analysis of the modifications in craniofacial skeleton development that may arise following diagnosis pediatric benign jaw tumors. A prospective was undertaken involving 53 patients younger than 18 years age, who presented for treatment at Department Maxillo-Facial Surgery, University Medicine and Pharmacy, Cluj-Napoca, with primary lesion between 2012 2022. total 28 odontogenic cysts (OCs), 14 tumors (OTs), 11 non-OTs were identified. At follow-up,...
Agastache species (Lamiaceae) are aromatic plants that used in traditional medicine for the treatment of gastrointestinal diseases and bacterial infections. Their phytochemical profile is characterized by presence essential oil, phenolic derivatives terpenoid compounds. In present study, polyphenolic composition antioxidant potential four (A. foeniculum, A. mexicana, scrophulariifolia, rugosa) one cultivar rugosa ‘After Eight’) were investigated. The total polyphenols content (TPC), caffeic...
Agastache species (Lamiaceae) are aromatic plants that used in traditional medicine for the treatment of gastrointestinal diseases and bacterial infections. Their phytochemical profile is characterized by presence essential oil, phenolic derivatives terpenoid compounds. In present study, polyphenolic composition antioxidant potential four (A. foeniculum, A. mexicana, scrophulariifolia, rugosa) one cultivar rugosa ‘After Eight’) were investigated. The total polyphenols content (TPC), caffeic...