A5016815153- Mycorrhizal Fungi and Plant Interactions
- Plant Pathogens and Fungal Diseases
- Bee Products Chemical Analysis
- Yeasts and Rust Fungi Studies
- Fungal Biology and Applications
- Meat and Animal Product Quality
- Food Industry and Aquatic Biology
- Lichen and fungal ecology
- Fungal Infections and Studies
- Nuclear Structure and Function
- Antifungal resistance and susceptibility
- RNA Research and Splicing
- Bioinformatics and Genomic Networks
- Insect and Arachnid Ecology and Behavior
- RNA and protein synthesis mechanisms
- Genomics and Chromatin Dynamics
- Machine Learning in Bioinformatics
- Slime Mold and Myxomycetes Research
- Infectious Diseases and Mycology
- Phytochemical and Pharmacological Studies
Hebei University of Science and Technology
2024-2025
Guiyang Medical University
2019-2025
Radboud University Nijmegen
2020-2025
Radboud University Medical Center
2020-2025
Affiliated Hospital of Guangdong Medical College Hospital
2025
Guangdong Medical College
2025
Qiannan Normal College For Nationalities
2025
Canisius-Wilhelmina Ziekenhuis
2020-2023
Affiliated Hospital of Guizhou Medical University
2019-2021
Guizhou Institute of Technology
2020
To understand whether any human-specific new genes may be associated with human brain functions, we computationally screened the genetic vulnerable factors identified through Genome-Wide Association Studies and linkage analyses of nicotine addiction found one de novo protein-coding gene, FLJ33706 (alternative gene symbol C20orf203). Cross-species analysis revealed interesting evolutionary paths how this had originated from noncoding DNA sequences: insertion repeat elements especially Alu...
Abstract Chaetothyriales is an ascomycetous order within Eurotiomycetes. The particularly known through the black yeasts and filamentous relatives that cause opportunistic infections in humans. All species are consistently melanized. Ecology habitats of highly diverse, often rather extreme terms exposition toxicity. Families defined on basis evolutionary history, which reconstructed by time divergence concepts comparative biology using stochastical character mapping a multi-rate Brownian...
Tiger nuts were enzymatically hydrolyzed by Alcalase and then separated purified ultrafiltration classification Sephadex G-15 fractionation to obtain tiger nut peptides. Their chemical antioxidant activities cytoprotective functions on HepG2 Caco-2 cells systematically evaluated in this study. The peptides (TNP) found perform excellent activity supported their cell behaviors, amino acid composition, morphological observation. Higher 1,1-diphenyl-2-picrylhydrazyl radical scavenging (DPPH•...
Antibody humanization is an essential part of converting animal-derived antibodies into clinical candidates however conventional CDR grafting techniques often faces challenges, especially when antigen-binding sites extend beyond regions. Additionally, the process tends to retain undesired non-human elements within In this study, we overcame these challenges by using our proprietary AI-predicted antigen-antibody complex algorithm effectively humanize a murine antibody. During AI-powered...
<title>Abstract</title> Based on the data from China Household Finance Survey (CHFS), this paper employs income expectation gap as an indicator to quantify psychological loss. It investigates impact of loss consumption behavior and its underlying mechanisms both historical social dimensions. The findings indicate that significantly restrains household expenditure in a persistent manner, with exerting more pronounced inhibitory effect. curtails by diminishing risk preference enhancing...
In eukaryotes, karyopherin beta superfamily proteins mediate nucleocytoplasmic transport of macromolecules. We investigated the evolutionary and transcriptional patterns these using bioinformatics approaches. No obvious homologs were found in prokaryotes, but an extensive set beta-karyopherin was yeast. Among 14 beta-karyopherins Saccharomyces cerevisiae, eight corresponded to their human orthologs directly without diversification, two lost, remaining four exhibited gene duplications by...
Abstract Fungi in the order Chaetothyriales are renowned for their ability to cause human infections. Nevertheless, they not regarded as primary pathogens, but rather opportunists with a natural habitat environment. Extremotolerance is major trend order, quite different from black yeasts Capnodiales which focus on endurance, an important additional parameter advancing toxin management. In ancestral ecology of rock colonization, association metabolite-producing lichens significant....
Some members of Chaetothyriales, an order containing potential agents opportunistic infections in humans, have a natural habitat nests tropical arboreal ants. In these black fungi, two types ant symbiosis are known, i.e. occurrence domatia inside living plants, or as components carton constructions made ant-chewed plant tissue. to explain differences between strains from association, we sequenced and annotated genomes newly described species, Incumbomyces lentus delicatus, compared with four...
Abstract Lichen thalli provide a long-lived and stable habitat for colonization by wide range of microorganisms. Increased interest in these lichen-associated microbial communities has revealed an impressive diversity fungi, including several novel lineages which still await formal taxonomic recognition. Among these, members the Eurotiomycetes Dothideomycetes usually occur asymptomatically lichen thalli, even if they share ancestry with fungi that may be parasitic on their host. Mycelia...
The prevalence of black fungi in the order Chaetothyriales has often been underestimated due to difficulty their isolation. In this study, three methods which are used isolate compared. Enrichment on aromatic hydrocarbon appears effective inhibiting growth cosmopolitan microbial species and allows appearance fungi. We miniaturized method for high-throughput purposes. new procedure saves time, consumes less space can process multiple samples simultaneously.
Abstract Background Black opportunists Phialophora verrucosa complex species can cause different disease types in competent and immunocompromised individuals, but are remarkably overrepresented CARD9‐related infections. Objectives To better understand the ecology potential pathogenicity of opportunistic reveal eventual genetic parameters associated with behaviour vivo profiles patients CARD9 immunodeficiency. Methods Genomes 26 strains belonging to six were sequenced. Using multilocus...
Sugarcane (Saccharum officinarum, Poaceae) is cultivated on a large scale in (sub)tropical regions such as Brazil and has considerable economic value for sugar biofuel production. The plant rich substrate endo- epiphytic fungi. Black yeasts the family Herpotrichiellaceae (Chaetothyriales) are colonizers of human-dominated habitats, particularly those toxins hydrocarbon pollutants, may cause severe infections susceptible human hosts. present study assessed diversity associated with sugarcane,...
<title>Abstract</title> The antioxidant activity of the peptides from tiger nut was investigated for first time. (TNP) were found to perform excellent supported by their chemical and cell behaviors, amino acid composition, morphological observation. Higher 1,1-diphenyl-2-picrylhydrazyl radical scavenging ferric ion reducing power observed in TNP with more hydrophobic acids compared traditional soybean peanut peptides. Furthermore, could effectively protect H<sub>2</sub>O<sub>2</sub>-induced...
Fungal infections and hypersensitivity represent two distinct yet interconnected host immune responses. While infection primarily activates innate pathways to combat pathogens opportunists, arises from exaggerated responses fungal allergens. This duality highlights the complex balance between defence against risk of an inappropriate response antigens. Allergens elicit allergic reactions in respiratory system, skin, gastrointestinal tract. Inhalation airborne propagules e.g., Aspergillus,...