A5102801913- Fungal Infections and Studies
- Plant Pathogens and Fungal Diseases
- Antifungal resistance and susceptibility
- Nail Diseases and Treatments
- Mycorrhizal Fungi and Plant Interactions
- Yeasts and Rust Fungi Studies
- Actinomycetales infections and treatment
- Infectious Diseases and Mycology
- Fungal and yeast genetics research
- Fungal Biology and Applications
- Sinusitis and nasal conditions
- Toxin Mechanisms and Immunotoxins
- Pneumocystis jirovecii pneumonia detection and treatment
- Animal Disease Management and Epidemiology
- Enzyme Production and Characterization
- Indoor Air Quality and Microbial Exposure
- Inflammatory Bowel Disease
- Insect and Arachnid Ecology and Behavior
- Vascular Tumors and Angiosarcomas
- Cervical Cancer and HPV Research
- Phytoplasmas and Hemiptera pathogens
- Oral Health Pathology and Treatment
- Plant Disease Resistance and Genetics
- Lichen and fungal ecology
- Synthesis and biological activity
Affiliated Hospital of Guizhou Medical University
2019-2025
Guiyang Medical University
2015-2025
Capital Medical University
2023
Westerdijk Fungal Biodiversity Institute
2015-2019
Seoul Metropolitan Government
2012
Chiba University Hospital
2008-2010
Chiba University
2006-2009
Nanyang Medical College
2009
Abstract A severe outbreak of highly virulent and multi-resistant dermatophytosis by species in the Trichophyton mentagrophytes / T . interdigitale complex is ongoing India. The correct identity etiologic agent a much-debated issue. In order to define limits, taxonomic study was undertaken combining molecular, morphological, physiological characteristics as evidence classification. Molecular show that T. s. str can be distinguished with difficulty from each other, but are unambiguously...
Abstract Chaetothyriales is an ascomycetous order within Eurotiomycetes. The particularly known through the black yeasts and filamentous relatives that cause opportunistic infections in humans. All species are consistently melanized. Ecology habitats of highly diverse, often rather extreme terms exposition toxicity. Families defined on basis evolutionary history, which reconstructed by time divergence concepts comparative biology using stochastical character mapping a multi-rate Brownian...
A resistant and hypervirulent dermatophyte from India has been described as a taxonomic novelty, Trichophyton indotineae, species of the mentagrophytes complex. Rapid detection correct identification closely similar dermatophytes with different predilections are essential for efficient clinical management. We evaluated efficacy rapid diagnostic methods environmental strains in T. The included Real-time-PCR, DermaGenius, LAMP, MALDI-ToF MS, using rDNA ITS sequences standard. results show that...
ABSTRACT The present paper includes a meta-analysis of literature data on 318 species fungi belonging to 34 orders in their response 8 antifungal agents (amphotericin B, caspofungin, fluconazole, itraconazole, ketoconazole, posaconazole, terbinafine, and voriconazole). Main trends MIC results at the ordinal level were visualized. European Committee Antimicrobial Susceptibility Testing Clinical & Laboratory Standards Institute (CLSI) clinical breakpoints used as staff gauge evaluate...
ABSTRACT The gut microbiota is closely associated with inflammatory bowel disease (IBD) and colorectal cancer (CRC). Probiotics such as Clostridium butyricum (CB) or Akkermansia muciniphila (AKK) have the potential to treat However, research on combined therapeutic effects immunomodulatory mechanisms of CB AKK in treating IBD CRC has never been studied. This study evaluates co-administration DSS/AOM-induced colitis-associated CRC. Our results indicate that compared mono-administration, not...
Abstract Fungi in the order Chaetothyriales are renowned for their ability to cause human infections. Nevertheless, they not regarded as primary pathogens, but rather opportunists with a natural habitat environment. Extremotolerance is major trend order, quite different from black yeasts Capnodiales which focus on endurance, an important additional parameter advancing toxin management. In ancestral ecology of rock colonization, association metabolite-producing lichens significant....
The Microsporum canis complex consists of one zoophilic species, M. canis, and two anthropophilic audouinii ferrugineum. These species are the most widespread zoonotic pathogens causing dermatophytosis in cats humans worldwide. To clarify evolutionary relationship between three explore potential host shift process, this study used phylogenetic analysis, population structure multispecies coalescent analyses, determination MAT idiomorph distribution, sexual crosses, macromorphology...
In vitro susceptibilities of ten clinical isolates, including five strains Cryptococcus neoformans var. grubii and Aspergillus fumigatus, were determined against nine sulfa drugs using a microdilution method. Among the tested media, minimum inhibitory concentration (MIC) values observed only in YNB medium: no detectable level MIC value less than 125 microg/ml was four remaining media species. Of drugs, which sulfaphenazole showed highest antifungal activity, for A. fumigatus C. were,...
Some members of Chaetothyriales, an order containing potential agents opportunistic infections in humans, have a natural habitat nests tropical arboreal ants. In these black fungi, two types ant symbiosis are known, i.e. occurrence domatia inside living plants, or as components carton constructions made ant-chewed plant tissue. to explain differences between strains from association, we sequenced and annotated genomes newly described species, Incumbomyces lentus delicatus, compared with four...
Since Carl Woese's discovery of archaea as a third domain life, numerous archaeal species have been discovered, yet diversity is poorly characterized. Culturing complicated, but several queries about cell biology, evolution, physiology, and need to be solved by culturing culture-dependent techniques. Increasing interest in demand for innovative methods has led various technological methodological advances. The current review explains frequent hurdles hindering uncultured isolation discusses...
Summary Aureobasidium pullulans and A. melanogenum are black‐yeast‐like surface colonisers commonly encountered as contaminants in the hospital. The species able to produce melanin which play a role protection against environmental stress irradiation. shows higher frequency opportunistic infections compared . Comparative pathogenicity of black yeasts between explain observed differences infection. Degrees melanisation thermotolerance were measured, virulence strains from different sources...
Candida albicans is a major fungal pathogen of humans. The most striking biological feature C. its phenotypic plasticity, allowing it to undergo morphological transitions in response various environmental cues. Transcription factors play critical roles the regulation transitions. Here, we report role opaque and filamentation inducer 1 (Ofi1), previously uncharacterized zinc-finger-containing protein encoded by gene orf19.4972, white-opaque switching filamentous growth. Over-expression OFI1...
Isolation and identification of Cryptococcus neoformans pathogenic yeast-like fungi from pigeon droppings has been taken for a long time requires various nutrients its growth. In this study, we attempted to establish rapid direct method Cr. dropping samples by nested-PCR using internal transcribed spacer (ITS) CAP64 CNLAC1 genes, polysaccharide capsule gene laccase-associated produce melanin pigment, respectively, which are common genes yeasts. The ITS were amplified in all yeasts, but was...
The prevalence of black fungi in the order Chaetothyriales has often been underestimated due to difficulty their isolation. In this study, three methods which are used isolate compared. Enrichment on aromatic hydrocarbon appears effective inhibiting growth cosmopolitan microbial species and allows appearance fungi. We miniaturized method for high-throughput purposes. new procedure saves time, consumes less space can process multiple samples simultaneously.
Abstract Dermatophytes and other members of Onygenales are unique in their ability to degrade keratin, affecting hair nails, the case human hosts, causing skin infections. Subtillisins essential proteases keratin assimilation, subtilisin-like protease 1 (SUB1) SUB3–7 specific for dermatophytes. eIF2α kinases serine-threonine that perform functions response infection, proteotoxicity, nutrient scavenging. The relatively conserved nature EIF2AK4 among fungi makes them potential evolutionary...
Diutina (Candida) rugosa is emerging as a causative agent of human infections. Recently some close relatives have been described, that is, D. mesorugosa, pseudorugosa, and neorugosa, which also implicated in infection. Phylogenetic relationships 24 clinical isolates the complex are reconstructed using multilocus sequence analysis five housekeeping genes, supplemented with phenotypic studies CandiSelect™ 4 Agar nutritional physiology. mesorugosa could not meaningfully be distinguished from...
ABSTRACT Fungal rhinosinusitis (FRS) is a common problem worldwide, with an increasing burden in arid climate regions. Aspergillus species are the most causative agents involved. In present study, we investigated prevalence, molecular characterization, and antifungal susceptibility of opportunists causing FRS Sudan on basis strains collected over period 5 years. β-Tubulin calmodulin sequencing were used for identification, profiles evaluated by protocol European Committee Antimicrobial...
Abstract A set of 185 strains Candida albicans from patients with vulvovaginal candidiasis (VVC) and non‐VVC clinical sources in southwest China was analysed. Strains were subjected to genotyping using CAI microsatellite typing amplification an intron‐containing region the 25S rRNA gene. Microsatellite genotypes showed high polymorphism, whereas those VVC dominated by few, closely similar genotypes. However, among strains, two particularly prevalent lung cancer. rDNA genotype dominant...
Genetic heterogeneity and drug susceptibility patterns of 43 Candida albicans isolates from patients with respiratory infections in China were compared those 52 Japanese patients. Of the strains, 17 genotype A, B, 8 C, 1 was E. Drug susceptibilities against amphotericin flucytosine, 3 azoles, micafungin strains compared. All susceptible to all drugs tested, two countries similar. Four showed trailing growth for azole antifungals; Chinese did not.