A5048121534- Environmental Toxicology and Ecotoxicology
- Carcinogens and Genotoxicity Assessment
- Aquatic Invertebrate Ecology and Behavior
- Electromagnetic Fields and Biological Effects
- Epigenetics and DNA Methylation
- Pharmaceutical and Antibiotic Environmental Impacts
- Marine Bivalve and Aquaculture Studies
- Parasite Biology and Host Interactions
- Insect and Arachnid Ecology and Behavior
- Insect and Pesticide Research
- Insect Utilization and Effects
- Crustacean biology and ecology
- Marine Biology and Environmental Chemistry
- Toxic Organic Pollutants Impact
- Marine Ecology and Invasive Species
- Heavy Metal Exposure and Toxicity
- Genetic diversity and population structure
- Microplastics and Plastic Pollution
- Genetically Modified Organisms Research
- Invertebrate Taxonomy and Ecology
- Molecular Biology Techniques and Applications
- Cancer-related gene regulation
- Water Quality and Pollution Assessment
- Nanoparticles: synthesis and applications
- DNA and Nucleic Acid Chemistry
Universität Innsbruck
2021-2023
University of Zagreb
2010-2021
Theodore Roosevelt High School
2018
Université de Bordeaux
2017
To address and to compare the respective impact of gold silver nanoparticles (Au Ag NPs) in soil invertebrate, earthworm Eisenia fetida was exposed containing 2, 10, 50 mg/kg Au both nanoparticulate ionic forms for 10 days. Both metal NPs were 2–15 times less bioavailable than their forms, displayed similar transfer coefficients from tissues. triggered onset an oxidative stress as illustrated by increased glutathione S-transferase levels, decreased catalase malondialdehyde concentrations....
Toxic effects of cadmium (Cd), a common soil pollutant, are still not very well understood, particularly in regard to its epigenetic impact. Therefore, the aim this study was assess DNA methylation changes and their persistence earthworm Lumbricus terrestris upon chronic low dose Cd exposure using sensitive amplification polymorphism (MSAP). Moreover, biomarker response fitness earthworms, as expression detoxification-related genes (metallothionein (MT) phytochelatin synthase (PCS))...
Exposure of different animal species to radiofrequency electromagnetic fields (RF-EMF) could cause various biological effects such as oxidative stress, genotoxic and dysfunction the immune system. However, there are a lack results on stress response genotoxicity in honey bee (Apis mellifera) after exposure RF-EMF. This study was performed investigate RF-EMF activity catalase, superoxide dismutase, glutathione S-transferase, lipid peroxidation level DNA damage larvae. Honey larvae were...
Metallothioneins (MTs) are multifunctional proteins occurring throughout the animal kingdom. While expression and transcriptional regulation of MTs is well-studied in vertebrates, mechanism MT activation still unknown for most invertebrates. Therefore, we examined wMT-2 gene patterns Lumbricus rubellus L. terrestris. Transcription levels, occupation DNA binding sites, putative regulators, promotor methylation were determined. We found that does not follow a circadian pattern. However,...
Abstract This study reports on the chromosome number and karyological characteristics of endangered species European crayfish, Astacus astacus A. leptodactylus (Decapoda, Astacidae), both native to Croatian freshwater habitats. The karyotype consists 2n = 176 180 chromosomes, respectively. haploid complement 52 metacentric, 35 metacentric-submetacentric, 1 acrocentric chromosomes. Fluorochrome staining with 4,6-diamino-2-phenylindole (DAPI) has revealed that karyotypes are characterized by...
Revealing long-term effects of contaminants on the genetic structure organisms inhabiting polluted environments should encompass analyses at population, molecular, and cellular level. Following this concept, we studied constitution zebra mussel populations from a (Dp) reference sites (Cl) river Drava, Croatia, applied microsatellite DNA damage (Comet assay, micronucleus test (MNT)). Additionally, mussels both were exposed to wastewater in laboratory for three days, was analyzed evaluate...
Banded murex, Hexaplex trunculus, is a marine gastropod whose reproductive fitness can be severely affected by very low concentrations of antifouling compound tributyltin (TBT). TBT has strong xenoandrogen impacts on snails, causing the development imposex (e.g., superimposition male sexual characteristic in females), thereby affecting entire populations. also known as DNA-demethylating agent and an obesogenic factor. The aim this study was to unravel interactions between bioaccumulation,...
Earthworms are well-established model organisms for testing the effects of heavy metal pollution. How DNA methylation affects cadmium (Cd) detoxification processes such as expression metallothionein 2 (MT2), however, is largely unknown. We therefore exposed Lumbricus terrestris to 200 mg concentrations Cd and 5-aza-2′-deoxycytidine (Aza), a demethylating agent, sampled tissue coelomocytes, cells innate immune system, 48 h. MT2 transcription significantly increased in Cd- Cd-Aza-treated...
Cage Exposure of European Sea Bass ( Dicentrarchus Labrax ) for in Situ Assessment Pollution-Related Genotoxicity Genotoxic effects are often the earliest signs pollution-related environmental disturbance. In this study, we used comet assay and micronucleus test to assess DNA damage erythrocytes sea bass labrax exposed pollution situ. Fish were collected from a fish farm Trogir Bay their cages placed at an unpolluted reference site Šolta (Nečujam Bay) polluted Vranjic (Kaštela four weeks. A...
Abstract PAC2 cell line is, along most of the developed zebrafish lines, poorly characterized concerning its response to genotoxicants. To define different forms genotoxic stress, we exposed cells model agents (benzo[ a ]pyrene, B[a]P, and ethyl methanesulfonate) subsequently monitored DNA damage alterations by using battery tests, including Comet assay, quantitative random‐amplified polymorphic amplified fragment length polymorphism. The expression several repair ( xpc , xpd hr23b rad51...
Exposure to radiofrequency electromagnetic fields (RF-EMF) at the operating frequencies of different communication devices can cause various biological effects. However, there is a lack studies on oxidative stress response and genotoxicity in honey bee (Apis mellifera) after exposure RF-EMF. In this study, we investigated DNA damage larvae situated waxcomb cells, exposed modulated RF-EMF 23 Vm-1. The glutathione S-transferase activity decreased, whereas catalase increased significantly upon...