- Weed Control and Herbicide Applications
- Thyroid Disorders and Treatments
- Legume Nitrogen Fixing Symbiosis
- Pesticide and Herbicide Environmental Studies
- Plant and animal studies
- Agronomic Practices and Intercropping Systems
- Genetically Modified Organisms Research
- Thyroid Cancer Diagnosis and Treatment
- Plant tissue culture and regeneration
- Ecology and Vegetation Dynamics Studies
- Nematode management and characterization studies
- Biological Control of Invasive Species
- Lymphoma Diagnosis and Treatment
- Allelopathy and phytotoxic interactions
- Immune Cell Function and Interaction
- Chronic Lymphocytic Leukemia Research
- Immunodeficiency and Autoimmune Disorders
- Evolution and Genetic Dynamics
- Growth Hormone and Insulin-like Growth Factors
- Insect-Plant Interactions and Control
- T-cell and B-cell Immunology
- Thyroid and Parathyroid Surgery
- Bone health and treatments
- Diabetes and associated disorders
- Erythrocyte Function and Pathophysiology
Rothamsted Research
2016-2025
University of Copenhagen
2021-2025
Agriculture and Horticulture Development Board
2020-2021
University of Warwick
2009-2021
Planta
2021
Coventry (United Kingdom)
2015
The University of Western Australia
2003-2009
Université Libre de Bruxelles
1984-2002
Erasmus Hospital
1989-1997
Universidad Libre de Colombia
1994
Durable crop protection is an essential component of current and future food security. However, the effectiveness pesticides threatened by evolution resistant pathogens, weeds insect pests. Pesticides are mostly novel synthetic compounds, yet target species often able to evolve resistance soon after a new compound introduced. Therefore, pesticide provides interesting case rapid under strong selective pressures, which can be used address fundamental questions concerning evolutionary origins...
Should the declining diversity of weed communities in conventionally managed arable fields be regarded as a problem? The answer to this question has tended divide researchers into those whose primary focus is on conserving farmland biodiversity and goals are dictated by control maximising yield. Here, we argue that, regardless how weeds perceived, there common ecological principles that should underpin any approach managing communities, and, based these principles, increasing in-field could...
To delineate the physiological effects of aging on basal levels and temporal patterns neuroendocrine secretions, 24-h profiles cortisol, thyroid-stimulating hormone (TSH), melatonin, prolactin, growth (GH) were simultaneously obtained at frequent intervals in eight healthy, active elderly men, age 67-84 yr young male adults, 20-27 yr. The study was preceded by an extended period habituation to laboratory conditions, sleep polygraphically recorded. Mean cortisol normal, but amplitude...
Summary A simulation study was conducted to examine the effect of pattern herbicide use on development resistance two herbicides with different modes action in finite weed populations. The effects size treatment area (analogous initial population), germination fraction and degree self‐pollination were investigated. results indicate that probability developing one or both decreases as area/initial population decreases. For areas 100 ha less an seedbank seeds m −2 frequencies genes 10 −6 ,...
Synthetic herbicides have been used globally to control weeds in major field crops. This has imposed a strong selection for any trait that enables plant populations survive and reproduce the presence of herbicide. Herbicide resistance must be minimized because it is limiting factor food security global agriculture. represents huge challenge will require great research efforts develop strategies as alternatives dominant almost exclusive practice weed by herbicides. Weed scientists, ecologists...
Abstract Intense selection by pesticides and antibiotics has resulted in a global epidemic of evolved resistance. In agriculture medicine, using mixtures compounds from different classes is widely accepted as optimal resistance management. However, this strategy may promote the evolution more generalist mechanisms. Here we test hypothesis at national scale an economically important agricultural weed: blackgrass ( Alopecurus myosuroides) , for which herbicide major economic issue. Our results...
Abstract Weeds are attractive models for basic and applied research due to their impacts on agricultural systems capacity swiftly adapt in response anthropogenic selection pressures. Currently, a lack of genomic information precludes elucidate the genetic basis rapid adaptation important traits like herbicide resistance stress tolerance effect evolutionary mechanisms wild populations. The International Weed Genomics Consortium is collaborative group scientists focused developing resources...
Summary Quantification of fitness differences between herbicide‐resistant and herbicide‐susceptible weeds permits better prediction herbicide resistance, the design weed management strategies to exploit those traits that result in reduced ecological performance. Reported here is first attempt compare germination seedling emergence characteristics one two phenotypes from a single population. A series experiments was carried out controlled conditions study seed Lolium rigidum possessing...
Summary Evolved resistance to herbicides is a classic example of ‘evolution in action’. This paper calls for greater integration ‘evolutionary‐thinking’ into herbicide research. integration, it argued, should lead weed scientists become less focused on simply describing and more driven towards deeper understanding the evolutionary forces that underpin evolution. I have attempted this short initiate debate how might be done. In first instance, highlighted widespread misunderstanding...
To delineate the effects of aging on basal and stimulated TSH secretion, we studied 24-h profile plasma levels response to TRH stimulation (200 μg TRH, iv) in eight healthy elderly men, aged 67–84 yr, normal young 20–27 yr. Subjects with thyroid antibodies against microsomal or thyroglobulin antigens were excluded. During study, blood was sampled at 15-min intervals. measured by an ultrasensitive immunoradiometric assay. Sleep polygraphically monitored, circadian pulsatile variations...