- Renal Transplantation Outcomes and Treatments
- Hematopoietic Stem Cell Transplantation
- Blood groups and transfusion
- T-cell and B-cell Immunology
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Hemoglobinopathies and Related Disorders
- Hepatitis B Virus Studies
- Erythrocyte Function and Pathophysiology
- Blood transfusion and management
- Immune Cell Function and Interaction
- Complement system in diseases
- Hepatitis C virus research
- Blood donation and transfusion practices
- Genomic variations and chromosomal abnormalities
- Acute Lymphoblastic Leukemia research
- Acute Myeloid Leukemia Research
- Chronic Lymphocytic Leukemia Research
- Immunotherapy and Immune Responses
- Diabetes and associated disorders
- Systemic Lupus Erythematosus Research
- Blood disorders and treatments
- Chronic Myeloid Leukemia Treatments
- Liver Disease Diagnosis and Treatment
- Cancer Genomics and Diagnostics
Medanta The Medicity
2012-2024
NHS Blood and Transplant
2023
Christie's
2021
Creative Commons
2021
DR. B.R.A. Institute Rotary Cancer Hospital
2010-2018
Medanta The Medicity
2011-2017
All India Institute of Medical Sciences Bhopal
2015
All India Institute of Medical Sciences Raipur
2015
All India Institute of Medical Sciences
2015
Indraprastha Apollo Hospitals
2007-2011
<b>Aims:</b> This study aims to establish biological reference interval for novel platelet parameters. <b>Settings and Design:</b> A total of 945 healthy individuals, age ranges from 18 64 years (881 males females) coming voluntary blood donation June August 2012 (3 months) were enrolled after exclusion rejection criteria. <b>Materials Methods:</b> The samples assayed by running in complete count + reticulocyte mode on the Sysmex XE-2100 hematology analyzer population was calculated using...
Antibody-mediated rejection is a critical factor in acute and chronic allograft rejection, with Human Leukocyte Antigen as the primary target of humoral immune response kidney transplants. In addition to HLA antibodies, non-HLA Abs also play significant role AMR. These Abs, which can either autoantigens or alloantigens, may be present pre-transplantation develop post-transplant. They are associated various types injury. The major include those directed against angiotensin II type 1 receptor,...
The objective of the study was to find incidence hemolysis in samples transported through a pneumatic tube system (PTS) at different speeds.This prospective observational done three phases: "short distance and high speed (115 m 3 m/s)", "long (225 m/s)" slow 2 m/s)". Fifty-two, 215 45 serum pairs, respectively, were evaluated these phases. A set tubes sent by PTS while other hand-carried. Samples analyzed for supernatant hemoglobin (Hb), potassium (K+) lactate dehydrogenase (LD).Mean transit...
Storage of red cells causes a progressive increase in hemolysis. In spite the use additive solutions for storage and filters leucoreduction, some amount hemolysis is still inevitable. The extent hemolysis, however, should not exceed permissible threshold even on 42(nd) day storage.Eighty units packed cells, 40 stored SAGM post leucoreduction ADSOL without filters, were evaluated plasma hemoglobin by HemoCue Plasma Hemoglobin analyzer collection 7(th), 14(th), 21(st), 28(th), 35(th) days...
ABO-incompatible live donor liver transplant (ABOi-LDLT) is being widely done to bridge the gap of demand and supply organs. Different desensitization regimes are used reduce titer blood group antibodies for successful accommodation graft. The authors cascade plasmapheresis (CP) bring down naturally occurring antibody 16 or lower. Four recipients ABOi-LDLT were groups O, B, B while donors A, AB, respectively. Desensitization protocol included immunosuppressive drugs plasmapheresis. CP...
Sir, The field of medicine has since infinity been associated with consistent discoveries thus leading to ever increasing list advancing technologies. When talking about transfusion medicine, the discovery blood group antigens marked revolutionising step in success transfusions. Following ABO by Landsteiner 1901,[1] next most important was that Rh 1939 and Weiner further description haemolytic disease new born Levine Stetson.[2] The antigen itself studied extensively its alleles...
Abstract EBV ‐associated PTLD is increasingly recognized as an important cause of morbidity and mortality in both solid organ hematopoietic stem cell transplant recipients. Mortality rates due to virus‐induced HLH are reported be quite high. We report a case child after liver transplantation who was successfully managed timely intervention. This highlights that measurement load by quantitative polymerase chain reaction assays aid the surveillance diagnosis early detection ‐induced ,...
Abstract Background: Sorafenib (SOR) is an oral multikinase inhibitor that targets tumor growth and angiogenesis. We previously reported progression-free survival (PFS) data from the primary analysis of NU07B1 (SABCS 2009 abstr 44), a phase 2b trial assessing combination SOR + paclitaxel (PAC) in patients with advanced breast cancer (BC). Here we report overall (OS) data, secondary endpoint. Methods: multinational (India, United States, Brazil) study HER2-negative locally or metastatic BC....
Harvest of hematopoietic progenitor cells via leukapheresis is being used increasingly for transplants in India. Adequate yield per kilogram body weight recipient required successful engraftment. Collection efficiency (CE) an objective quality parameter to assess the program. In this study, we calculated CE ComTec cell separator (Fresenius Kabi, Germany) using two different formulae (CE1 and CE2) analyzed various patient procedural factors, which may affect it.One hundred one consecutive...
<b>Background:</b> CD71 is a marker that has been usually used for identifying dysplasia in the erythroid series. We have tried to evaluate expression of various types acute leukemias. <b>Materials and Methods:</b> studied 48 patients leukemia, which 25 were myeloid leukemia (AML), 13 precursor B-acute lymphoblastic (B-ALL), 8 T-ALL, 2 mixed phenotype (T/myeloid) as per WHO classification. <b>Results:</b> found was most prevalent AMLs (84%), followed by T-ALL (50%) least B-ALL (30%)....
<b>Background:</b> The present study addressed the interesting findings of supplemental evaluation hepatitis B seroyield donors. <b>Materials and Methods:</b> Each blood donor sample was tested for anti-human immunodeficiency virus type I (HIV-I)/HIV II (HIV-II), HBsAg, anti-hepatitis C (HCV) antibody by enhanced chemiluminescence method subjected to individual donor-nucleic acid testing (NAT) HIV-I, (HBV), HCV. NAT test performed using eSAS system, Procleix Ultrio Assay, Novartis...