A5100420427- Functional Brain Connectivity Studies
- Attention Deficit Hyperactivity Disorder
- Advanced Neuroimaging Techniques and Applications
- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Genetics, Aging, and Longevity in Model Organisms
- Liver Disease Diagnosis and Treatment
- Circadian rhythm and melatonin
- Sleep and related disorders
- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
- Neuroscience and Neuropharmacology Research
- Effects of Radiation Exposure
- Congenital heart defects research
- Saffron Plant Research Studies
- Regulation of Appetite and Obesity
- Hepatitis C virus research
- Sleep and Wakefulness Research
- Dental Radiography and Imaging
- Pharmacovigilance and Adverse Drug Reactions
- Orthopaedic implants and arthroplasty
- Spaceflight effects on biology
- Heart Rate Variability and Autonomic Control
- Dental Implant Techniques and Outcomes
- Hepatitis B Virus Studies
Wenzhou Medical University
2009-2024
First Affiliated Hospital of Wenzhou Medical University
2009-2024
Fudan University
2019
Chinese People's Armed Police General Hospital
2016
Chinese People's Armed Police Force
2016
Abstract Purpose: To establish a 3D finite element model of mandible with dental implants for immediate loading and to analyze stress distribution in bone around different diameters. Materials Methods: Three models, embedded thread (ITI, Straumann, Switzerland) diameters 3.3, 4.1, 4.8 mm, respectively, were developed using CT scanning self‐developed Universal Surgical Integration System software. The von Mises strain the implant–bone interface calculated ANSYS software when loaded 150 N...
Hepatocellular carcinoma (HCC) is the major threat to human health, and disruption of circadian clock genes implicated in hepatocarcinogenesis. This study examined dysregulation metallothioneins achieved HCC (n = 24), peri-HCC tissues 24) as compared with normal livers 36). Total RNA was extracted reverse transcribed. Real-time RT-qPCR performed determine expression interest. The results demonstrated downregulation metallothionein-1 (MT-1), MT-2, metal transcription factor-1 (MFT-1) Peri-HCC...
This active, open observational study aimed to investigate adverse drug reactions (ADRs) associated with six commonly used antiepileptic drugs (AEDs) in southern Chinese outpatients epilepsy from 2003 2015. The Wenzhou Epilepsy Follow-Up Registry Database (WEFURD) was established by a single center China January record AED efficacy and the ADRs registered diagnosed epilepsy. We reviewed data of who had only taken one or more AEDs, namely, carbamazepine (CBZ), valproate (VPA), lamotrigine...
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disease featuring executive control deficits as prominent neuropsychological trait. Executive functions are implicated in multiple sub-networks of the brain; however, few studies examine these whole ADHD. By combining resting-state functional MRI and graph-based approaches, we systematically investigated connectivity patterns among four control-related networks, including frontoparietal network (FPN),...
Abstract Attention-deficit/hyperactivity disorder has been identified to involve the impairment of large-scale functional networks within grey matter, and recent studies have suggested that white which also encodes neural activity, can manifest intrinsic organization similar matter. However, alterations in matter attention-deficit/hyperactivity remain unknown. We recruited a total 99 children, including 66 drug-naive patients 33 typically developing controls aged from 6 14, characterize...
Autism spectrum disorders (ASD) are a family of childhood-onset neurodevelopmental with complex genetic mechanisms underlying their aetiology. The aim this case-control study was to evaluate the effect catechol-O-methyltransferase (COMT) gene Val158Met polymorphism on ASD risk in Chinese Han population.The COMT detected by polymerase chain reaction-restriction fragment length children (≤ 18 years old) and healthy control subjects.The frequency Val158/Val158 genotype (22/186; 11.8%)...
Background Evidence shows people living with CHB even a normal ALT (40U/L as threshold) suffer histological disease and there is still little research to evaluate the potential benefit of antiviral benefits in them. Methods We retrospectively examined 1352 patients who underwent liver biopsy from 2017 2021 then obtained their 1-year follow-up data analyze. Results levels were categorized into high low, thresholds set at >29 for males >15 females through Youden’s Index. The...
Airway vagal nerves play a predominant role in the neural control of airway, and augmented airway activity is known to important roles pathogenesis some chronic inflammatory diseases. Several lines evidence indicate that dysfunctional central orexinergic system closely related severity diseases, however, whether orexins affect unknown. This study investigates how orexin-A regulates medullary preganglionic neurons (AVPNs). The expression orexin receptor type 1 (OX1R) 2 (OX2R) was examined...