ABSTRACT Background To correlate between immunohistochemical expression of tumor‐infiltrating lymphocytes (TILs), tumor‐associated macrophages (TAMs), and natural killer (NK) cells with the AJCC 8th edition TNM staging system other disease‐modifying clinico‐pathological variables. Methods The representative histology sections tumor invasive margin (IM) core (TC) were selected according to International Immuno‐Oncology Biomarker Working Group subjected immunohistochemistry antibodies for TILs...

Summary Obstructive sleep apnea is characterized by intermittent hypoxia and disruption, leading to accelerated neurodegenerative changes cognitive decline. Serum amyloid‐beta tau proteins, which are markers for Alzheimer's disease, have been reported increase in patients with obstructive apnea. This study compared the serum levels of proteins 46 cognitively normal 30 healthy controls. Sleep parameters severity were determined using overnight polysomnography. Aβ40, Aβ42, total...

Sample size calculation is an important step for carrying out any research. Most of the sample estimating utilities/applications use standard deviation differences in their formula paired design, which usually not reported published articles. Researchers are left to pooled (SDp) instead using differences. The gives a more accurate estimate design. can be determined from p-value or confidence intervals (CI), In this paper, we have described and illustrated with example how determine CIs....

Introduction: Intraoperative cytology in ovarian tumors involves collecting cell samples from the sample sent during surgery and quickly examining them for diagnostic information. Frozen section provides rapid diagnosis to guide intraoperative patient management. The indications of frozen are identification tissue, evaluation margins lymph nodes metastasis. Aim: To evaluate comparative utility squash smear, scrape smear imprint with tumour. Materials methods: tissue clinico-radiologically...

Abstract Systemic lupus erythematosus (SLE) is an autoimmune condition with the potential to impact all bodily organ systems. Lupus enteritis represents a rare complication observed in subset of patients who exhibit nonspecific gastrointestinal symptoms. Typically, diagnosis relies on imaging findings such as localized or widespread thickening bowel wall, abnormal enhancement distinctive “comb sign” indicating engorged mesenteric vessels, presence ascites, and lymph node enlargement....

There is a knowledge gap in the relationship between sleep duration and myopia. Since modifiable risk factor, its association with development progression of myopia has implications for public health. This review was conducted accordance 2020 Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA) guidelines. The bibliographic databases PubMed Scopus were searched published studies on These December 2023 no date or study design limits. relevant literature extracted met priori...

Abstract Background The International Academy of Cytology (IAC) Yokohama system is a recently proposed for reporting breast cytology by fine needle aspiration biopsies (FNAB). Multiple studies are needed to confirm the risk malignancy (ROM) various categories this system. present article accuracy IAC in our center. Methods Over period 1 year (September 2018‐August 2019), all cases masses assessed FNAB and histological correlation were studied retrospectively. Sensitivity, specificity,...

HemoCue point of care devices has been extensively used in screening for anemia blood banking. can estimate hemoglobin (Hb) both from venous as well capillary blood. However, the suitability Hb estimation donor selection is unclear.The aims this study were to evaluate variance difference measurement compared automated cell counter and assess accuracy two different models (201 301) against measurements blood.HemoCue 201 301 evaluated by a comparison methods Sysmex XP-100 three-part analyzer...

Focused studies in different geographic regions would delineate the underlying biological differences and molecular alterations non-small cell lung cancer (NSCLC) worldwide. Previous literature have documented limited characterization by studying a minimal number of markers. This study was done to evaluate expression multiple immunomarkers including diagnostic, prognostic, predictive markers NSCLC for its characterization.This an observational conducted on 60 consecutive cases NSCLC....

Abstract Background The Paris System of Reporting Urine Cytology aims to screen samples for HGUC and provide a universally acceptable reporting format urine cytology specimens. However, studies detailing the reproducibility this system, especially on cyto‐centrifuge preparations, are lacking. Methods 149 voided received in Department Pathology were reviewed independently by five cytopathologists. To estimate overall agreement, Gwet's AC AC1statistics between each pair raters used. measure...

Pneumoperitoneum creation for laparoscopic surgery increases the intraabdominal pressure and causes alveolar atelectasis. We investigated influence of an increase in intra-abdominal (IAP) on ventilatory mechanical power (MP) delivery during pneumoperitoneum cholecystectomy.

The perception appears to flow in a continuous pattern but evidence suggest that may involve discrete temporal sampling of peripheral cues. Stroud's perceptual moment theory proposes occurs moments; however, more experimental is required support this theory. present study characterized the decision function for asynchrony detection using variable stimulus-onset asynchronies (SOAs). Fourteen healthy volunteers (twelve males and two females), ages 21.5 ± 3.8 years (mean SD) participated study....

Biofilms in a cochlear implant can lead to severe intracranial complications like meningitis, and it cause failure, thus requiring an explant, leading financial social loss. Meticulous sterility the intraoperative period proper hygiene postoperative need be emphasized Patient. We report case of 4-year-old girl child who presented with recurrent episodes wound dehiscence through site following asymptomatic after course antibiotics, finally treated debridement flap reconstruction under general...

Complex sclerosing lesion (CSL)/radial scar of breast is a benign entity that can pose diagnostic challenge due to resemblance carcinoma on imaging. Hamartoma are uncommon tumors, composed disorganized mixture glandular, fibrous, and adipose tissues, which exhibit classical imaging characteristics. Here we describe case concomitant CSL hamartoma in left beast, presented as suspicious mass but was ultimately confirmed be histopathology with 4 years documented stability.

Classification of breast lesions into different cytological groups can accurately be done using the International Academy Cytology (IAC) Yokohama System for reporting cytopathology. Fine needle aspiration biopsy (FNAB) has been considered to primary investigation in detecting cancers, especially low-cost settings. The main objective this study was prospectively re-confirm diagnostic accuracy FNAB IAC system. Additionally, separate secondary subgroup analysis confirm excluding lymph-node...

Background Coronavirus disease 2019 (COVID-19) has currently emerged as a global threat and significant public health issue. The role of simulation-based training (SBT) during such pandemic becomes more relevant for teaching team approach building capacity especially when there is to care workers due aerosol generation huge demand manpower the pandemic. Objective To assess effectiveness program in improving knowledge concept teamwork involved airway management suspected or confirmed COVID-19...

Neurocysticercosis is a serious endemic zoonosis resulting in increased cases of seizure and epilepsy humans. The genesis clinical manifestations the disease through experimental animal models poorly exploited. monkeys may prove useful for purpose due to their behavior cognitive responses mimicking man. In this study, neurocysticercosis was induced two rhesus each with 12,000 6,000 eggs, whereas three were given placebo. higher dose developed hyperexcitability, epileptic seizures, muscular...