A5014968517- Astrophysics and Star Formation Studies
- Stellar, planetary, and galactic studies
- Astronomy and Astrophysical Research
- Astro and Planetary Science
- Advanced biosensing and bioanalysis techniques
- Astrophysical Phenomena and Observations
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Sirtuins and Resveratrol in Medicine
- Bacteriophages and microbial interactions
- CRISPR and Genetic Engineering
- Ubiquitin and proteasome pathways
- Herpesvirus Infections and Treatments
- Gamma-ray bursts and supernovae
- Peptidase Inhibition and Analysis
- Toxoplasma gondii Research Studies
- Scientific Research and Discoveries
- Spacecraft and Cryogenic Technologies
- RNA Research and Splicing
- Bacterial Genetics and Biotechnology
- Cellular Mechanics and Interactions
- Bacillus and Francisella bacterial research
- Identification and Quantification in Food
- RNA and protein synthesis mechanisms
- Biosensors and Analytical Detection
Public Health Department
2025
Wuhan Academy of Agricultural Sciences
2025
Chinese Academy of Sciences
2010-2024
National Astronomical Observatories
2010-2024
Center for Excellence in Molecular Plant Sciences
2021-2023
Shenzhen Institutes of Advanced Technology
2021-2023
University of Chinese Academy of Sciences
2021-2023
State Key Laboratory of Synthetic Chemistry
2022
Peking University
2018-2021
Macquarie University
2021
Transcription activation is established through extensive protein-protein and protein-DNA interactions that allow an activator to engage remodel RNA polymerase. SoxS, a global transcription activator, diversely regulates subsets of stress response genes with different promoters, but the detailed SoxS-dependent initiation mechanisms remain obscure. Here, we report cryo-EM structures three complexes (SoxS-TACI, SoxS-TACII SoxS-TACIII) comprising Escherichia coli polymerase (RNAP), SoxS protein...
1. Accurate sex identification of one-day-old chicks is crucial in layer poultry production. Establishing an early sexing method during the chicken embryonic period essential for animal welfare. However, PCR-based has limitations terms specialised equipment and time-consuming.2. This study presents a rapid, simple fluorescent visual technique based on Loop-mediated isothermal amplification (LAMP)-clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 12a...
•A highly abundant and dynamic acetylation is discovered in Streptomyces coelicolor.•Quantitative acetylome succinylome analyses coelicolor.•The bimodification proteins are enriched multiple metabolic pathways. Lysine acylations reversible ubiquitous post-translational modifications that play critical roles regulating cellular processes. In the current study, acetylation, besides succinylation, was uncovered a soil bacterium, coelicolor. By affinity enrichment using anti–acetyl-lysine...
Timely and accurate detection of SARS-CoV-2 variants concern (VOCs) is urgently needed for pandemic surveillance control. Great efforts have been made from a mass scientists in increasing the sensitivity operability, reducing turn-around time cost. Here, we report nucleic acid testing-based method aiming to detect discriminate mutations by combining RT-RPA CRISPR-Cas12a detecting assays (RRCd). With limit 10 copies RNA/reaction, RRCd was validated 194 clinical samples, showing 89% positive...
Abstract Recent studies have revealed that the onset age for presence of multiple stellar populations (MPs) in star clusters seems to correspond disappearance extended main-sequence turnoff young clusters, a pattern associated with rotations. A speculative suggestion is MPs might be caused by magnetic brake, evolutionary effect linked rotation. In this work, we use massive cluster NGC 419 as testbed. We examined if its magnetically baked MS stars would exhibit MPs. Using deep ultraviolet and...
We present the first multiband photometry for semidetached eclipsing binary AO Serpentis, observed on seven nights between 2009 April and July at Weihai Observatory of Shandong University. By using 2003 version Wilson–Devinney code, photometric solutions Ser a similar object V338 Her were (re)deduced. The spectral types orbital periods are A2 P = 0.8793 days Ser, F1V 1.3057 Her. results reveal that two binaries low mass ratio systems, whose secondary components fill their Roche lobes....
Thanks to the precise astrometric measurements of proper motions by Gaia mission, a new tidal stellar stream has been discovered in northern hemisphere. The distribution star count shows that is approximately $80$ degrees long and $1.70$ wide. Observations $21$ member stars, including 14 RR Lyrae indicate an eccentric retrograde orbit with $e=0.58$. low metallicity, high total energy, large angular momentum suggest it associated merging event Sequoia. This discovery suggests possibility...
Abstract Multiple stellar populations (MPs) with different chemical compositions are not exclusive features of old globular clusters (older than 10 Gyr). Indeed, recent studies reveal that younger (∼2–6 Gyr-old) in the Magellanic Clouds also exhibit star-to-star variations among evolved stars. However, whether MPs present less-evolved dwarfs these intermediate-age is still unclear. In this work, we search for GK-type ∼2 Gyr cluster NGC 1978, which youngest MPs. We exploit deep ultraviolet...
New photometry of the neglected eclipsing binary FR Orionis was obtained in 2012 November and December. Using updated Wilson–Devinney program, photometric elements were deduced from two-color light curves. The results indicate that this system is a semi-detached binary, with mass ratio 0.325(± 0.002) fill-out factor primary fp = 73.5(± 0.2)%. oscillating curves imply Ori may be an EA (oEA)-type star rapidly pulsating, mass-accreting component. After we removed theoretical observations,...
Recent discoveries of bimodal main sequences (MSs) associated with young clusters (with ages $\lesssim 1$ Gyr) in the Magellanic Clouds have drawn a lot attention. One prevailing formation scenarios attributes these split MSs to distribution stellar rotation rates, most stars belonging rapidly rotating population. In this scenario, only small fraction populating secondary blue sequence are slowly or non-rotating stars. Here, we focus on MS cluster NGC 1850. We compare cumulative number...
Sirtuins are a group of NAD
Abstract The color–magnitude diagrams of young star clusters show that, particularly at ultraviolet wavelengths, their upper main sequences (MSs) bifurcate into a sequence comprising the bulk population and blue periphery. spatial distribution stars is crucial to understanding reasons for these distinct stellar populations. This study uses high-resolution photometric data obtained with Hubble Space Telescope distributions populations in seven Magellanic Cloud clusters. cumulative radial...
Reproducing color-magnitude diagrams (CMDs) of star-resolved galaxies is one the most precise methods for measuring star formation history (SFH) nearby back to earliest time. The upcoming big data era poses challenges traditional numerical technique in its capacity deal with vast amounts data, which motivates us explore feasibility employing machine learning networks this field. In study, we refine synthetic CMD method a state-of-the-art theoretical stellar evolution model simulate...
Abstract Reproducing color–magnitude diagrams (CMDs) of star-resolved galaxies is one the most precise methods for measuring star formation history (SFH) nearby back to earliest time. The upcoming big data era poses challenges traditional numerical technique in its capacity deal with vast amounts data, which motivates us explore feasibility employing machine learning networks this field. In study, we refine synthetic CMD method a state-of-the-art theoretical stellar evolution model simulate...
Abstract Recent submillimeter dust thermal emission observations have unveiled a significant number of inter-arm massive molecular clouds in M31. However, the effectiveness this technique is limited to its sensitivity, making it challenging study more distant galaxies. This introduces an alternative approach, utilizing optical extinctions derived from space-based telescopes, with focus on forthcoming China Space Station Telescope (CSST). We first demonstrate capability method by constructing...
Helium variations are common features of globular clusters (GCs) with multiple stellar populations. All the formation scenarios predict that secondary population stars enhanced in helium but exact content depends on polluters. Therefore, searching for a star cluster is straightforward method to understand if it hosts populations or not, and constrain scenario. Although this topic has been well explored Galactic GCs, GCs beyond Milky Way challenging study because their large distances. This...
Abstract Asymmetric cell division (ACD) produces morphologically and behaviorally distinct cells is the primary way to generate diversity. In model bacterium Caulobacter crescentus , polarization of scaffold-signaling hubs at swarmer staked poles constitutes basis ACD. However, mechanisms involved in formation these remain elusive. Here, we show that a swarmer-cell-pole scaffold, PodJ, forms biomolecular condensates both vitro living via phase separation. The intrinsically disordered...
HD 32297 is a young A-type star with bright edge-on debris disk. The dust thermal emission spectral energy distribution and scattered starlight spectrum are simultaneously modeled in terms of porous cometary grains. Our modeling suggests that, similar to the solar system, disk around may have an inner warm ring outer cold which seen other disks as well.
Abstract Timely and accurate detection of SARS-CoV-2 variants concern (VOCs) is urgently needed for pandemic surveillance control. However, current methods are limited by the low sensitivity, long turn-around time or high cost. Here, we report a nucleic acid testing-based method aiming to detect discriminate VOCs combining R T- PA C RISPR-Cas12a d etecting assays (RRCd). With limit 10 copies RNA/reaction, RRCd was validated in 204 clinical samples, showing 99% positive predictive agreement...
Timely and accurate detection of SARS-CoV-2 variants concern (VOCs) is urgently needed for pandemic surveillance control. However, current methods are limited by the low sensitivity, long turn-around time or high cost. Here, we report a nucleic acid testing-based method aiming to detect discriminate VOCs combining RT-RPA CRISPR-Cas12a detecting assays (RRCd). With limit 10 copies RNA/reaction, RRCd was validated in 204 clinical samples, showing 99% positive predictive agreement 100% negative...