A5101911752- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal cell carcinoma treatment
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Thyroid Disorders and Treatments
- Angiogenesis and VEGF in Cancer
- MRI in cancer diagnosis
- Liver Disease and Transplantation
- Cardiovascular Function and Risk Factors
- Soft tissue tumor case studies
- Sepsis Diagnosis and Treatment
- Phytochemistry and Biological Activities
- Thermal Regulation in Medicine
- Cardiovascular Syncope and Autonomic Disorders
- Gastrointestinal motility and disorders
- Enhanced Recovery After Surgery
- Chromatin Remodeling and Cancer
- Parathyroid Disorders and Treatments
- Blood groups and transfusion
- High Altitude and Hypoxia
- Urologic and reproductive health conditions
Nanjing Medical University
2016-2025
Jiangsu Province Hospital
2016-2025
First Affiliated Hospital of Xi'an Jiaotong University
2024-2025
Renji Hospital
2008-2021
Shanghai Jiao Tong University
2008-2021
iQIYI (China)
2021
Nanjing Maternity and Child Health Care Hospital
2017
Background Early stage hepatocellular carcinoma (HCC) is the ideal candidate for resection in patients with preserved liver function; however, cancer will recur half of these and no reliable prognostic tool has been established. Purpose To investigate effectiveness radiomic features predicting tumor recurrence after early HCC. Materials Methods In total, 295 (median age, 58 years; interquartile range, 50–65 221 men) who underwent contrast material–enhanced CT curative HCC that met Milan...
Identifying patients with intrahepatic cholangiocarcinoma (ICC) likely to benefit from immunochemotherapy, the new front-line treatment, remains challenging. We aimed unveil a novel radiotranscriptomic signature that can facilitate treatment response prediction by multi-omics integration and multi-scale modelling. analyzed bulk, single-cell spatial transcriptomic data comprising 457 ICC identify an immune-related score (IRS), followed decoding its immune context. mapped radiomics profiles...
Abstract Abnormal fluctuations in thyroid function within the reference range were strongly associated with increased all-cause mortality. This study aimed to analyze association between oxidative balance score (OBS) and free thyroxine (FT4) thyrotropin (TSH) euthyroid adults, as well their interrelationships 5727 adults selected from National Health Nutrition Examination Survey (NHANES). Weighted linear regression investigated potential of OBS FT4 TSH. In addition, COX proportional hazard...
<title>Abstract</title> Abnormal fluctuations in thyroid function within the reference range were strongly associated with increased all-cause mortality. This study aimed to analyze association between oxidative balance score (OBS) and biomarkers of euthyroid adults further investigate whether status affects mortality by regulating these biomarkers. 5727 selected from National Health Nutrition Examination Survey (NHANES). Weighted linear regression investigated potential OBS free thyroxine...
Cabozantinib and ramucirumab are approved for the treatment of adults with hepatocellular carcinoma (HCC) following prior sorafenib treatment; is restricted to use in patients serum alpha-fetoprotein (AFP) ≥ 400 ng/mL. This matching-adjusted indirect comparison evaluated efficacy safety both drugs after HCC AFP Individual patient data (IPD) from CELESTIAL trial (cabozantinib) population-level REACH-2 (ramucirumab) were used. To align REACH-2, population was limited who received first-line...
Cholangiocarcinoma is a rare tumor accounting for less than 2% of all human malignancies.1 The hilar cholangiocarcinoma (HCC) was first described by Klatskin, and thus called Klatskin tumor. HCC the most common bile tract tumor, 40% to 60% these tumors, which affect approximately 7500 Americans each year.2–4 clear cell variant occurs at variable frequencies among large series HCC. vacuolated appearance cells due cytoplasmic accumulation amount glycogen or lipids dissolved routine...
Abstract Objective This study aimed to explore the pathological characteristics of lymph nodes around inferior mesenteric artery in rectal cancer and its risk factors impact on tumor staging. Methods 485 patients underwent proctectomy surgery were collected this study. Clinical features patients, including gender, age, BMI, size, type, differentiation, nerve invasion, nodes, marker, examinations, analyzed. Results A total cases included There 29 with IMA-LN metastasis; metastasis rate was...
The progress toward clinical translation of imaging biomarkers for mass-forming intrahepatic cholangiocarcinoma (MICC) is slower than anticipated. Questions remain on the biologic behaviour underlying traits. We developed and validated imaging-based prognostic systems resected MICCs with an appraisal tumour immune microenvironment (TIME) underpinning patient-specific traits.Between January 2009 December 2019, a total 322 patients who underwent dynamic computed tomography/magnetic resonance...
Objective To determine the risk factors for uterine arteriovenous malformation (AVM) in Chinese women, providing basis clinical diagnosis and management. Methods A total of 28 cases with AVM were retrospectively analyzed to investigate relationship duration postoperative bleeding, abortion frequency, history intrauterine operation other AVM. Results Age, method surgery, days hospitalization frequency as well gestational age significantly correlated AVM. Days independent...
Objective To observe the CT and MRI results of solitary fibrous tumors(SFT) in abdomen pelvis, analyze their characteristic imaging, improve accuracy diagnosis understanding disease. Methods Retrospective analysis 18 cases confirmed by pathology from January 2008 to June 2017[9 men, 9 women, age 41- 71(53.0±10.6) years old] through imaging findings clinical pathological data patients with pelvic SFT. Among patients, 13 received dynamic 5 MRI. The tumor size(maximum...