A5069306849- Advanced Radiotherapy Techniques
- Radiation Detection and Scintillator Technologies
- Radiation Therapy and Dosimetry
- Radiation Effects in Electronics
- Radiation Effects and Dosimetry
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Semiconductor materials and devices
- Effects of Radiation Exposure
- Global Cancer Incidence and Screening
- Advancements in Semiconductor Devices and Circuit Design
- Radioactive Decay and Measurement Techniques
- Nuclear Physics and Applications
- Prostate Cancer Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Integrated Circuits and Semiconductor Failure Analysis
- Cancer Risks and Factors
- Cancer Cells and Metastasis
- Radiomics and Machine Learning in Medical Imaging
- Carcinogens and Genotoxicity Assessment
- Mathematical Biology Tumor Growth
- Statistical Methods in Clinical Trials
- Prostate Cancer Treatment and Research
- Head and Neck Cancer Studies
Instituto de Investigación Biosanitaria de Granada
2015-2024
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2011-2023
Universidad de Granada
2003-2021
Complejo Hospitalario Universitario de Granada
2016-2020
Odense University Hospital
2013
European Organisation for Research and Treatment of Cancer
2013
Barcelona Biomedical Research Park
2011-2012
This paper reports the development, evaluation and validation of DosiTag, a dosimetric platform based on Near Field Communication (NFC) technology. The designed system comprises two main parts: passive NFC sensing tag as dosimeter unit, which includes commercial P-channel MOSFET transistor radiation sensor; an NFC-enabled smartphone running custom-developed application reader unit. Additionally, cloud service messaging protocol Message Queue Telemetry Transport (MQTT) has been implemented...
Purpose The response to radiation typically used in radiotherapy treatments has been experimentally evaluated for three samples of two phototransistors (BPW85B and OP505A) PIN photodiodes types (VTB8440BH BPW34S). Methods To that end, a staggered irradiation cycle applied which included dose rate values from 0.81 4.87 cGy/s, achieving total absorbed 21.4 Gy. have irradiated with linear accelerator the relations between induced photocurrent average instantaneous rates, accumulated charge...
The outcome of radiotherapy treatment might be further improved by a better understanding individual variations in tumor radiosensitivity and normal tissue reactions, including the bystander effect. For many tumors, however, definitive cure cannot achieved, despite availablity more effective cancer treatments. Therefore, any improvement efficacy will undoubtedly benefit significant number patients. Many experimental studies measure component cell death after radiotherapy, which highlights...
Safe quality control of radiotherapy treatments lies in reliable dosimetric sensors. Currently, ionization chambers and solid-state diodes along with electrometers as readout systems are accomplishing this task. In work, we present a well-known low-cost semiconductor sensor, the light-dependent resistor (LDR), an alternative to existing sensing devices for dosimetry. To demonstrate this, complete characterization response radiation commercial LDRs has been conducted terms sensitivity,...
In this work we have developed a simulation tool, based on the PENELOPE code, to study response of MOSFET devices irradiation with high-energy photons. The energy deposited in extremely thin silicon dioxide layer has been calculated. To reduce statistical uncertainties, an ant colony algorithm implemented drive application splitting and Russian roulette as variance reduction techniques. way, uncertainty reduced by factor approximately 5, while efficiency is increased above 20. As...
One of the major advantages proton or ion beams, applied in cancer treatment, is their excellent depth-dose profile exhibiting a low dose entrance channel and distinct maximum (Bragg peak) near end range tissue. In region Bragg peak, where protons ions are almost stopped, experimental studies with low-energy particle beams thin biological samples may contribute valuable information on effectiveness stopping region. Such experiments, however, require beam optimization special dosimetry...
In this work, a procedure, based on Monte Carlo techniques, to analyse the effect tumour control probability of time interval between surgery and postoperative radiotherapy is presented. The approach includes growth as well survival cells undergoing fractionated radiotherapy. Both processes are described in terms binomial distribution. We have considered two different models, exponential Gompertz, parameters which been fixed reproduce clinical outcome corresponding retrospective study for...
A Monte Carlo tool which permits the simulation of screening mammography programmes is developed. Various statistical distributions describing different parameters involved in problem are used: characteristics population under study, a tumour growth model and for detection based on such as sensitivity specificity depends woman's age. We reproduce results actual programmes. The enables us to find out configuration (the age women who attend trials frequency) produces maximum benefits with...
We propose and study a new model aimed at describing the low-dose hyper-radiosensitivity phenomenon appearing in survival curves of different cell lines.The uses induced repair assumption, considering that critical dose which this mechanism begins to act varies from given population. The proposed is compared with linear-quadratic modified model, commonly used literature taken into account heuristic way. curve for MCF-7 line human breast cancer measured low absorbed doses uncertainties these...
In this work we estimate the therapeutic gain that could be obtained using a radiotherapy programme in which doses were based on radiosensitivity test was able to predict final response of normal tissues radiation for each particular patient. To date, no good assay has been demonstrated and by way example use an initial DNA damage. The individualized propose is increase dose delivered patients showing resistant behaviour adoption alternative programmes or careful monitoring those whom...
The performance of radiography in the Intensive Care Unit (ICU) may be associated with a certain level radiation exposure for staff and patients unit. Little evidence on levels is available literature. However, healthcare professionals ICUs at our centre tend to leave room during radiographic examinations, potentially compromising patient care.
Extraction of radiation dose information from MOSFET (RADFET) based dosimetry systems usually relies on biasing the during readout at zero temperature coefficient drain current ( \mbi IZTC), measured before irradiation. This can vary due to accumulated doses and thermal fluctuations, which degrades dosimetric accuracy. work presents a method reduce drift related this IZTC shift. It is with two carefully chosen currents according model suitable for MOSFETs. An experiment including irradiation...