Maurizio Casarrubea

ORCID: 0000-0002-3278-6621
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About
Contact & Profiles
Research Areas
  • Neurotransmitter Receptor Influence on Behavior
  • Neuroendocrine regulation and behavior
  • Stress Responses and Cortisol
  • Neuroscience and Neuropharmacology Research
  • Memory and Neural Mechanisms
  • Receptor Mechanisms and Signaling
  • Behavioral and Psychological Studies
  • Olfactory and Sensory Function Studies
  • Nicotinic Acetylcholine Receptors Study
  • Neural dynamics and brain function
  • Cannabis and Cannabinoid Research
  • Animal Behavior and Welfare Studies
  • Primate Behavior and Ecology
  • Pain Mechanisms and Treatments
  • Circadian rhythm and melatonin
  • Autism Spectrum Disorder Research
  • Sleep and Wakefulness Research
  • Sensory Analysis and Statistical Methods
  • Neurobiology and Insect Physiology Research
  • Advanced Text Analysis Techniques
  • Animal Behavior and Reproduction
  • Biochemical Analysis and Sensing Techniques
  • Animal Vocal Communication and Behavior
  • Animal Ecology and Behavior Studies
  • Mast cells and histamine

University of Palermo
2015-2024

Tecnologie Avanzate (Italy)
2007-2019

University of Florence
2017

Clinica Luganese Moncucco
2005-2015

Nicotine is one of the most addictive drugs abuse. Tobacco smoking a major cause many health problems, and first preventable death worldwide. Several findings show that nicotine exerts significant aversive as well well-known rewarding motivational effects. Less certain anatomical substrate mediates or enables aversion. Here, we acute induces anxiogenic-like effects in rats at doses investigated (0.1, 0.5, 1.0 mg/kg, i.p.), measured by hole-board apparatus manifested behaviors such decreased...

10.3389/fncel.2015.00197 article EN cc-by Frontiers in Cellular Neuroscience 2015-06-01

The first step in a behavioral study is represented by the organization of suitable ethogram, that is, formal description individual components behavior. Then, each component such repertoire can be quantified (e.g., how many times it occurs, its duration, percent distribution, latency, etc.). However, our contention possibility to describe behavior living being means hundreds or even thousands numbers concerning isolated components, disjointed from comprehensive architecture, does not imply...

10.3389/fpsyg.2019.00881 article EN cc-by Frontiers in Psychology 2019-04-24

Summary Aim The transgenic D1 CT ‐7 mouse is one of the best‐characterized animal models Tourette's syndrome ( TS ), exhibiting spontaneous tic‐like Head‐Body Twitches HBT ) and deficits in sensorimotor gating. This study aimed at evaluating behavioral dynamics these mutants their potential relevance to . Methods behavior Wild Type littermates was firstly assessed by considering frequencies durations. To detect recurrent real‐time sequences, multivariate T‐pattern analysis employed. Analyses...

10.1111/cns.12789 article EN CNS Neuroscience & Therapeutics 2018-01-03

Nicotine addiction is a serious public health problem causing millions of deaths worldwide. Serotonin (5-hydroxytryptamine; 5-HT) involved in central nervous system (CNS) nicotine effects, and it has been suggested as promising pharmacological target for smoking cessation. In this regard, what particularly interesting are the 5-HT2A receptors (5-HT2ARs) lateral habenula (LHb), area that we showed to be under strong 5-HT2AR-modulation. Single-cell extracellular recording LHb neurons was used...

10.3390/ijms21051873 article EN International Journal of Molecular Sciences 2020-03-09

The physiological mechanisms underlying the complex interplay between life stressors and metabolic factors is receiving growing interest being analyzed as one of many contributing to depressive illness. brain histaminergic system modulates neuronal activity extensively we demonstrated that its integrity necessary for peripheral signals such bioactive lipid mediator oleoylethanolamide (OEA) exert central actions. Here, investigated role histamine interaction with OEA in response chronic...

10.1016/j.ynstr.2021.100317 article EN cc-by Neurobiology of Stress 2021-03-18
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