A5059786789- Hormonal and reproductive studies
- Sexual function and dysfunction studies
- Urinary Bladder and Prostate Research
- Sexual Differentiation and Disorders
- Ovarian function and disorders
- Sexuality, Behavior, and Technology
- Hypothalamic control of reproductive hormones
- Menopause: Health Impacts and Treatments
- Prostate Cancer Diagnosis and Treatment
- Estrogen and related hormone effects
- Sperm and Testicular Function
- Pharmacology and Obesity Treatment
- Eating Disorders and Behaviors
- LGBTQ Health, Identity, and Policy
- Adipose Tissue and Metabolism
- Reproductive Biology and Fertility
- Neuroendocrine regulation and behavior
- Menstrual Health and Disorders
- Muscle metabolism and nutrition
- COVID-19 Impact on Reproduction
- Pelvic floor disorders treatments
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Stress Responses and Cortisol
- Regulation of Appetite and Obesity
- Reproductive Health and Technologies
University of Florence
2016-2025
Azienda Ospedaliero-Universitaria Careggi
2016-2024
Istituto Nazionale Biostrutture e Biosistemi
2016-2024
Gender Studies
2020-2023
Ospedale Policlinico San Martino
2022
Sapienza University of Rome
2021
Fondazione Umberto Di Mario
2016-2020
Italian Society of Periodontology and Implantology
2008-2020
New York Proton Center
2020
Florence (Netherlands)
2020
The pandemic of new severe acute respiratory syndrome (SARS) due to coronavirus (CoV) 2 (SARS-CoV-2) has stressed the importance effective diagnostic and prognostic biomarkers clinical worsening mortality. Epidemiological data showing a differential impact SARS-CoV-2 infection on women men have suggested potential role for testosterone (T) in determining gender disparity outcomes.To estimate association between T level outcomes (defined as conditions requiring transfer higher or lower...
How is the semen quality of sexually active men following recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection?Twenty-five percent with recent SARS-Cov-2 infections and proven healing were oligo-crypto-azoospermic, despite absence virus RNA in semen.The presence SARS-CoV-2 human its role contagion after disease 2019 (COVID-19) still unclear. So far, studies evaluating occurrence infected or recovered are scarce included a limited number participants.A...
Abstract This Position Statement has been endorsed by the International Menopause Society, The Endocrine European and Andropause Society for Sexual Medicine, Study of Women's Health, North American Federacion Latinoamericana de Sociedades Climaterio y Menopausia, Royal College Obstetricians Gynecologists, Endocrinology, Australia, Australian New Zealand Gynecologists.*
By real-time RT-PCR and Western blot analysis, we found that phosphodiesterase type 5 (PDE5) mRNA protein abundance was several fold higher in human male than female reproductive tracts. The highest level (>1 x 10(7) molecules/microg total RNA) detected corpora cavernosa (CC), where PDE5 immunolocalized both muscular endothelial compartment. possible role of androgens regulating expression studied using a previously established rabbit model hypogonadotropic hypogonadism. In this model,...
Benign prostate hyperplasia is the most common disease in aging male, often comorbid with erectile dysfunction. Phosphodiesterase type 5 (PDE5) inhibitors (sildenafil, tadalafil, and vardenafil) decrease lower urinary tract symptoms patients dysfunction BPH. We studied PDE5 expression activity human bladder PDE5i effects both vitro (human rat) vivo (rat). highly expressed rat immunolocalized vascular endothelium muscle fibers. Sildenafil, vardenafil blocked 70% of total cGMP-catabolizing...
Metabolic syndrome (MetS) and benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS) are often associated. One of their common denominators is hypogonadism. However, testosterone supplementation limited by concerns for potential side effects. The objective was to determine whether MetS-associated prostate alterations prevented supplementation. We used a previously described animal model MetS, obtained feeding male rabbits high-fat diet (HFD) 12 weeks. Subsets HFD were treated...