A5056173815- Diabetes Treatment and Management
- Diabetes Management and Research
- Diet and metabolism studies
- Metabolism, Diabetes, and Cancer
- Pancreatic function and diabetes
- Nutritional Studies and Diet
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipokines, Inflammation, and Metabolic Diseases
- Pharmacology and Obesity Treatment
- Diabetes and associated disorders
- Diet, Metabolism, and Disease
- Sexual function and dysfunction studies
- Hormonal and reproductive studies
- Cardiovascular Function and Risk Factors
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Neuropeptides and Animal Physiology
- Nitric Oxide and Endothelin Effects
- Heart Rate Variability and Autonomic Control
- Regulation of Appetite and Obesity
- Blood Pressure and Hypertension Studies
- Advanced Glycation End Products research
- Blood properties and coagulation
- Cardiovascular Disease and Adiposity
- Receptor Mechanisms and Signaling
- Adipose Tissue and Metabolism
University of Campania "Luigi Vanvitelli"
2016-2025
University of Strathclyde
2016-2019
Diabetes Australia
2019
East China University of Science and Technology
2019
University of Córdoba
2017
University of Palermo
2017
Instituto Maimónides de Investigación Biomédica de Córdoba
2017
University of Naples Federico II
2007-2016
Sapienza University of Rome
2015
Italian Society of Periodontology and Implantology
2009-2010
The metabolic syndrome has been identified as a target for dietary therapies to reduce risk of cardiovascular disease; however, the role diet in etiology is poorly understood.To assess effect Mediterranean-style on endothelial function and vascular inflammatory markers patients with syndrome.Randomized, single-blind trial conducted from June 2001 January 2004 at university hospital Italy among 180 (99 men 81 women) syndrome, defined by Adult Treatment Panel III.Patients intervention group (n...
Circulating levels of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) are elevated in diabetic patients. We assessed the role glucose regulation circulating IL-6, TNF-alpha, interleukin-18 (IL-18) subjects with normal or impaired tolerance (IGT), as well effect antioxidant glutathione.Plasma were acutely raised 20 control 15 IGT maintained at mmol/L for 5 hours while endogenous insulin secretion was blocked octreotide. In subjects, plasma IL-18 rose (P<0.01) within 2 clamp...
Context Obesity is an independent risk factor for cardiovascular disease, which may be mediated by increased secretion of proinflammatory cytokines adipose tissue. Objective To determine the effect a program changes in lifestyle designed to obtain sustained reduction body weight on markers systemic vascular inflammation and insulin resistance. Design Setting Randomized single-blind trial conducted from February 1999 2002 at university hospital Italy. Patients One hundred twenty premenopausal...
To explore the possibility that oscillating glucose may outweigh A1C levels in determining risk for cardiovascular diabetes complications.A euinsulinemic hyperglycemic clamp at 5, 10, and 15 mmol/l was given increasing steps as a single "spike" or between basal high over 24 h normal subjects type 2 diabetic patients. Flow-mediated dilatation, marker of endothelial function, plasma 3-nitrotyrosine 24-h urinary excretion rates free 8-iso PGF2 alpha, two markers oxidative stress, were measured...
Visceral fat is a key regulator site for the process of inflammation, and atherosclerotic lesions are essentially an inflammatory response.Fifty-six healthy premenopausal obese women (age range 25 to 44 years, body mass index 37.2+/-2.2, waist hip ratio 0.78 0.92) 40 age-matched normal weight were studied. Compared with nonobese women, had increased basal concentrations tumor necrosis factor-alpha (TNF-alpha, P<0.01), interleukin-6 (IL-6, P-selectin (P<0.01), intercellular adhesion...
Healthy lifestyle factors are associated with maintenance of erectile function in men.To determine the effect weight loss and increased physical activity on endothelial functions obese men.Randomized, single-blind trial 110 men (body mass index > or =30) aged 35 to 55 years, without diabetes, hypertension, hyperlipidemia, who had dysfunction that was determined by having a score 21 less International Index Erectile Function (IIEF). The study conducted from October 2000 2003 at university...
Postprandial hyperglycemia may be a risk factor for cardiovascular disease. We compared the effects of two insulin secretagogues, repaglinide and glyburide, known to have different efficacy on postprandial hyperglycemia, carotid intima-media thickness (CIMT) markers systemic vascular inflammation in type 2 diabetic patients.We performed randomized, single-blind trial 175 drug-naive patients with diabetes mellitus (93 men 82 women), 35 70 years age, selected from population 401 who...
Low-carbohydrate and low-fat calorie-restricted diets are recommended for weight loss in overweight obese people with type 2 diabetes.To compare the effects of a low-carbohydrate Mediterranean-style or diet on need antihyperglycemic drug therapy patients newly diagnosed diabetes.Single-center, randomized trial. Randomization was computer-generated unstratified. Allocation concealed sealed study folders held central, secure location until participants gave informed consent. Participants...
Adhesion molecules, particularly intracellular adhesion molecule (ICAM)-1, vascular cell (VCAM)-1, and E-selectin, have been associated with cardiovascular disease. Elevated levels of these molecules reported in diabetic patients. Postprandial hypertriglyceridemia hyperglycemia are considered risk factors for disease, evidence suggests that postprandial may induce an increase circulating molecules. However, the distinct role two is a matter debate. Thirty type 2 patients 20 normal subjects...