A5101679552- Respiratory Support and Mechanisms
- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Mechanical Circulatory Support Devices
- Vibrio bacteria research studies
- Climate Change and Health Impacts
- Infection Control and Ventilation
- Aquaculture disease management and microbiota
- Antimicrobial Resistance in Staphylococcus
- Antimicrobial Peptides and Activities
- Sepsis Diagnosis and Treatment
- Neuroscience of respiration and sleep
- Palliative Care and End-of-Life Issues
- COVID-19 and healthcare impacts
- Bacterial biofilms and quorum sensing
- Bacterial Identification and Susceptibility Testing
- Agriculture and Farm Safety
- Veterinary Pharmacology and Anesthesia
- Aquaculture Nutrition and Growth
- Educational Technology in Learning
- Ear Surgery and Otitis Media
- Anesthesia and Sedative Agents
- Hydrogen's biological and therapeutic effects
- Marine animal studies overview
Fundación Canaria de Investigación Sanitaria
2022-2024
Hospital Universitario de Gran Canaria Doctor Negrín
2014-2024
Universidad de Las Palmas de Gran Canaria
2004-2024
Instituto de Salud Carlos III
2014-2024
Centro de Investigación Biomédica en Red
2022-2024
Département Santé Animale
2023
St. Michael's Hospital
2014
Oxygen therapy is currently used as a supportive treatment in septic patients to improve tissue oxygenation. However, oxygen can exert deleterious effects on the inflammatory response triggered by infection. We postulated that use of high concentrations may be partially responsible for worsening sepsis-induced multiple system organ dysfunction an experimental clinically relevant model sepsis. Sprague-Dawley rats. Sepsis was induced cecal ligation and puncture. Sham-septic controls (n = 16)...
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing profound health, economic, and social problems worldwide. Management of personal protective equipment (PPE) its potential limited availability have created concerns about the increased risks for healthcare professionals at hospitals nursing homes. Ozone a powerful oxidant agent. The objectives this study were to examine effects ozone treatment on PPE contaminated with SARS-CoV-2, explore whether relative...
The Canary Islands are a ciguatoxin (CTX) hotspot with an established official monitoring for the detection of CTX in fish flesh from authorised points first sale. Fish caught by recreational fishermen not officially tested and consumption toxic viscera or could lead to ciguatera poisoning (CP). objectives this study were determine presence CTX-like toxicity relevant species archipelago, compare levels liver examine possible factors involved their toxicity. Sixty amberjack (Seriola spp.), 27...
Development of antibiotic resistance in bacteria is a problem great concern. It important to establish the convenience antimicrobial susceptibility tests animal infections. The aim this study was test antibiotics Pseudomonas strains isolated from chronic canine otitis externa. We tested 23 Pseudomonas: 19 Ps. aeruginosa, three fluorescens and one spp. most effective were tobramycin (100% susceptible), marbofloxacin (91.3%) ceftazidime (91.3%). Ticarcillin gentamicin, commonly used for...
Objectives: Pulmonary endothelial cell injury is central to the pathophysiology of acute lung injury. Mechanical ventilation can cause disruption and injury, even in absence preexisting inflammation. Platelet-endothelial adhesion molecule-1 a transmembrane protein connecting adjacent cells. We hypothesized that injurious mechanical will increase circulating endothelial-derived microparticles, defined as microparticles positive for platelet-endothelial molecule-1, which could serve potential...
Sepsis is the most common cause of acute respiratory distress syndrome, a severe lung inflammatory disorder with an elevated morbidity and mortality. syndrome involve release mediators to systemic circulation, propagating cellular molecular response affecting distal organs, including brain. Since it has been reported that sepsis contribute brain dysfunction, we investigated brain-lung crosstalk using combined experimental in vitro airway epithelial cell injury model. Conditioned medium...
Abstract Introduction Most patients with sepsis and acute lung injury require mechanical ventilation to improve oxygenation facilitate organ repair. Mast cells are important in response infection resolution of tissue injury. Since tryptase secreted from mast has been associated fibrosis, we hypothesized that would be involved the early development ventilator-induced pulmonary fibrosis a clinically relevant model sepsis-induced Methods Prospective, randomized, controlled animal study using...
Endothelial cell injury is an important component of acute lung injury. Platelet-endothelial adhesion molecule-1 (PECAM1) a transmembrane protein that connects endothelial cells to one another and can be detected as soluble, truncated (sPECAM1) in serum. We hypothesized injurious mechanical ventilation (MV) leads shedding PECAM1 from resulting increasing sPECAM1 levels the systemic circulation.We studied 36 Sprague-Dawley rats two prospective, randomized, controlled studies (healthy septic)...
A total of 67 strains coagulase positive staphylococci isolated from healthy dogs and suffering otitis externa were studied. Twenty-two isolates (five hound 17 companion dogs) 45 (14 31 dogs). Presumptive identification was attempted using the following tests: production acetoin, anaerobic utilization mannitol, acid presence beta-galactosidase, growth on P agar supplemented with different concentrations acriflavine. Susceptibility to 16 antibiotics determined. Most effective imipenem,...
The purpose of this research was to develop reference values for haematological and biochemical variables in the Canary camel breed (Camelus dromedarius). 114 clinically healthy dromedary camels were assessed. Age, sex, pregnancy status also recorded. range red blood cells (RBCs) 8.45 - 13.65 X106/µL, haemoglobin (HGB) 10.61 15.29 g/dL, packed cell volume (PCV) 19.93 32.51 %, white (WBCs) 7.35 18.36 X103/µL. A correlation established between concentration (g/dl) obtaining a linear regression...
On the 21st of May 2023, a dead adult male sperm whale ( Physeter macrocephalus ) 13 m in length and estimated weight around 18,000 kg was reportedly stranded at Playa Los Nogales, La Palma, Canary Islands, Spain. A necropsy performed 48hpm. 50 cm diameter 9.5 coprolite found obstructing caudal colon-rectal lumen. Necro-hemorrhagic lesions were heart muscles three different bacteria intestinal origin isolated identified Edwarsiella tarda , Hathewaya limosa Clostridium perfringens ). It is...
On intensive fish farms, 10% of the population dies exclusively from pathogens, and Photobacterium damselae subsp. Piscicida (Ph. Piscicida), bacteria causing pasteurellosis in marine aquaculture, is one major pathogens involved. The objective this study was to obtain new probiotic strains against order limit use chemotherapy, avoiding environmental repercussions generated by abusive these products. In study, 122 were isolated gills intestines different species later evaluated vitro...
Abstract A strain of Alcaligenes faecalis A12C ( A. A12C) isolated from Argyrosomus regius is a probiotic in fish. Previous experiments showed that had inhibitory effects on the growth multidrug-resistant bacteria. We aimed to confirm whether safe and has adequate intestinal colonization experimental rats, evaluate its efficacy an animal model peritonitis . used 30 male randomly divided into 6 groups n = 5): three (HA7, HA15, HA30) received drinking water (6 × 10 8 CFU/mL) for 7 days,...
(1) Background: Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) continues to cause profound health, economic, and social problems worldwide. The management disinfection of materials used daily in health centers common working environments have prompted concerns about the control disease 2019 (COVID-19) infection risk. Ozone is a powerful oxidizing agent that has been widely processes for decades. aim this study was assess optimal conditions ozone treatment elimination...
The current COVID-19 pandemic is causing profound health, economic, and social problems worldwide. global shortage of medical personal protective equipment (PPE) in specialized centers during the outbreak demonstrated need for efficient methods to disinfect recycle them times emergency. We have previously described that high ozone concentrations destroyed viral RNA an inactivated SARS-CoV-2 strain within a few minutes. However, dosages active are still unknown. present study aimed evaluate...
Intensive fish farms are often affected by different organisms that produce infectious diseases. To control this situation, antibiotics have been used with negative repercussions for the environment and health. As an alternative to this, probiotics show more effective respectful results environment. The aim of project is obtain new potentially probiotic strains against one most relevant pathogens marine aquaculture, vibrios. These bacterial were isolated from gills intestines European...