A5025192546- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Chronic Disease Management Strategies
- Diabetes Management and Education
- Asthma and respiratory diseases
- Pelvic floor disorders treatments
- Systemic Lupus Erythematosus Research
- Diabetes Management and Research
- Sepsis Diagnosis and Treatment
- Maternal and Neonatal Healthcare
- Patient Satisfaction in Healthcare
- Frailty in Older Adults
- Pneumonia and Respiratory Infections
- Pregnancy and preeclampsia studies
- Blood Pressure and Hypertension Studies
- Urinary Tract Infections Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pulmonary Hypertension Research and Treatments
- Public Health and Environmental Issues
- Organ Donation and Transplantation
- Allergic Rhinitis and Sensitization
- Intensive Care Unit Cognitive Disorders
- Clinical Nutrition and Gastroenterology
- Medication Adherence and Compliance
- Urinary Bladder and Prostate Research
Health Research Institute of the Balearic Islands
2020-2024
Universidad de La Laguna
2021-2024
Red de Investigación en Actividades Preventivas y Promoción de la Salud
2023-2024
Hospital Universitario Nuestra Señora de Candelaria
2018-2022
Hospital Universitario de Gran Canaria Doctor Negrín
2009-2016
Corporació Sanitària Parc Taulí
2014
Statistical Service
2014
Universidad de Las Palmas de Gran Canaria
2011-2012
Pediatric Nephrology of Alabama
2010
University of Ilorin Teaching Hospital
1995
Passive and active immunity transfer through human milk (HM) constitutes a key element in the infant's developing immunity. Certain infectious diseases vaccines have been described to induce changes immune components of HM.
Although much has evolved in our understanding of the pathogenesis and factors affecting outcome patients with acute respiratory distress syndrome (ARDS), still there is no specific pharmacologic treatment for ARDS. Several clinical trials have evaluated utility corticoids but none them demonstrated a definitive benefit due to small sample sizes, selection bias, patient heterogeneity, time initiation or duration therapy. We postulated that adjunctive persistent ARDS intravenous dexamethasone...
To assess the potential association of functional polymorphism rs1801274 in receptor IIa for Fc portion immunoglobin G (FcγRIIa) gene (FCGR2A-H131R) with susceptibility to and severity community-acquired pneumonia (CAP).Multicenter prospective observational study.Four university hospitals Spain.FCGR2A-H131R was determined 1,262 patients CAP 1,224 subject control group.Severe sepsis recorded 366 patients. No significant differences genotype or allele frequencies were seen among pneumococcal...
The role of mannose-binding lectin (MBL) deficiency ( MBL2 ; XA/O and O/O genotypes) in host defences remains controversial. surfactant proteins (SP)-A1, -A2 -D, other collectins whose genes are located near , part the first-line lung defence against infection. We analysed MBL on susceptibility to pneumococcal infection existence linkage disequilibrium (LD) among four genes. studied 348 patients with community-acquired pneumonia (P-CAP) 2,110 controls. A meta-analysis genotypes P-CAP...
Oxygen therapy is currently used as a supportive treatment in septic patients to improve tissue oxygenation. However, oxygen can exert deleterious effects on the inflammatory response triggered by infection. We postulated that use of high concentrations may be partially responsible for worsening sepsis-induced multiple system organ dysfunction an experimental clinically relevant model sepsis. Sprague-Dawley rats. Sepsis was induced cecal ligation and puncture. Sham-septic controls (n = 16)...
Background Type 2 diabetes mellitus (T2DM) is a chronic disease in which health outcomes are related to decision making by patients and care professionals. Objective This study aims assess the effectiveness of internet-based multicomponent interventions support all actors involved with T2DM primary care. Methods The INDICA an open, community-based, multicenter trial random allocation usual or intervention for patients, professionals care, combined both. In participants received educational...
Background Toll-like receptors (TLRs) are critical components for host pathogen recognition and variants in genes participating this response influence susceptibility to infections. Recently, TLR1 gene polymorphisms have been found correlated with whole blood hyper-inflammatory responses pathogen-associated molecules associated sepsis-associated multiorgan dysfunction acute lung injury (ALI). We examined the association of common sepsis-derived complications an independent study serum levels...
The aim of this study is to validate the comprehensive model crowding posited by Baum and Paulus (1987) establish weighting each factor in assessment satisfaction with tourist settings. 486 participants completed scales assessing at last setting visited. structural equation obtained showed that social stimulation, privacy level, behavioral constraints, characteristics are indicators evaluation impact setting, explains crowding. Crowding does not have a significant effect on experience;...
Abstract Background Chronic obstructive pulmonary disease (COPD) has been proposed as a of accelerated aging. Several cross-sectional studies have related shorter telomere length (TL), marker biological aging, with COPD outcomes. Whether shortening over time relates to worse outcomes in patients, is not known. Methods Relative (T/S) was determined by qPCR DNA samples from peripheral blood 263 patients at baseline and up 10 years post enrolment. Yearly clinical lung function data 134 least...
Abstract Background Foley catheters have been subject to limited development in the last few decades. They fulfil their basic function of draining urine from bladder but cause other associated problems. T‐Control is a new silicone catheter with an integrated fluid control valve whose design aims reduce risks catheterization by multifactorial approach. The general purpose this study determine effectiveness, comfort, and experience patient catheterized T‐Control® compared patients conventional...
This study assesses the effectiveness of different interventions knowledge transfer and behaviour modification to improve type 2 diabetes mellitus patients' (T2DM) reported outcomes measures (PROMs) in long-term.
Background. There are no previous population-based studies assessing the prevalence of Blomia tropicalis (BT). This investigation analyzes sensitization to BT and its contribution asthma related diseases among young adults in Canary Islands. Material methods. From a random sample 9506 adults, aged between 20 44, who had previously answered short respiratory questionnaire, further 20% was drawn. All participants filled an extensive they underwent spirometry bronchial hyperresponsiveness (BHR)...
To evaluate the prevalence of and risk factors for asthma related conditions in Canaries, Spain.From a randomised sample 9506 adults aged 20-44 years who answered short questionnaire, random corresponding to 20% original was taken. Subjects classified as symptomatic previous survey were not included also invited participate. The subjects completed respiratory underwent spirometry, bronchial hyperresponsiveness (BHR) test, skin tests immunoglobulin E (IgE) measurements.The 593 subjects....
Objective. To determine the incidence of pneumonia and associated factors in a single-center systemic lupus erythematosus (SLE) cohort. Methods. We included all our SLE patients [1997 American College Rheumatology (ACR) criteria] with ≥ 1 event, 196 age sex-matched controls no events. Cumulative clinical data, weighted Systemic Lupus International Collaborating Clinics/ACR damage index (wSLICC/ACR-DI), comorbidities, risk for were retrospectively collected. The standardized ratio (SIR) was...
The product (DSP) of the distance walked (meters) and minimum oxygen saturation obtained during 6-minute walk test (6MWT) has been proposed as a predictor mortality in idiopathic pulmonary fibrosis bronchiectasis not related to cystic fibrosis.The aim this study was determine DSP's ability predict patients with chronic obstructive disease (COPD) at outpatient level compare it BODE index meters 6MWT.Descriptive observational cohort COPD being treated pulmonology clinics. Each completed 6MWT...