- Bacterial biofilms and quorum sensing
- Perovskite Materials and Applications
- Water Treatment and Disinfection
- Conducting polymers and applications
- Microbial Community Ecology and Physiology
- Quantum Dots Synthesis And Properties
- Wastewater Treatment and Nitrogen Removal
- interferon and immune responses
- Coccidia and coccidiosis research
- Viral Infections and Vectors
- Veterinary medicine and infectious diseases
- Advancements in Battery Materials
- Hematopoietic Stem Cell Transplantation
- Acute Myeloid Leukemia Research
- Chalcogenide Semiconductor Thin Films
- Chronic Myeloid Leukemia Treatments
- Tardigrade Biology and Ecology
- Trace Elements in Health
- Fibroblast Growth Factor Research
- Gut microbiota and health
- Heme Oxygenase-1 and Carbon Monoxide
- Retinoids in leukemia and cellular processes
- Biocrusts and Microbial Ecology
- Biosensors and Analytical Detection
- Viral Infections and Outbreaks Research
Northeast Agricultural University
2022-2025
Shanghai Jiao Tong University
2022-2025
Nanjing University
2019-2024
Ningbo University of Technology
2022-2024
Materials Science & Engineering
2024
State Key Laboratory of Pollution Control and Resource Reuse
2019-2024
Anhui Agricultural University
2024
Chongqing Medical University
2024
Kunshan Govisionox Optoelectronic (China)
2023-2024
Guangxi Medical University
2024
Inhibition of total histone deacetylases (HDACs) was phenomenally associated with the prevention diabetic cardiomyopathy (DCM). However, which specific HDAC plays key role in DCM remains unclear. The present study designed to determine whether can be prevented by inhibition HDAC3 and elucidate mechanisms prevents DCM. Type 1 diabetes OVE26 age-matched wild-type (WT) mice were given selective inhibitor RGFP966 or vehicle for 3 months. These then killed immediately months later cardiac...
Abstract Elevated tumor suppressor p53 expression has been associated with heart diseases, including the diabetic heart. However, its precise role in pathogenesis of cardiomyopathy (DCM) remains unclear. We hypothesized that development DCM is attributed to up-regulated p53-mediated both early cardiac cell death and persistent senescence, glycolytic angiogenetic dysfunctions. The present study investigated effect inhibition specific inhibitor pifithrin-α (PFT-α) on mechanisms. Type 1...
The growing interest in cost-effective and high-performing perovskite solar cells (PSCs) has driven extensive research. However, the challenge lies upscaling PSCs while maintaining high performance. This study focuses on achieving uniform compact films without pinholes interfacial voids during from small to large-area modules. Competition nucleation at concavities with various angles rough-textured substrates gas-pumping drying process, coupled different rates across expansive film,...
Abstract We have shown cardiac protection by metallothionein (MT) in the development of diabetic cardiomyopathy (DCM) via suppression cell death cardiac‐specific MT‐overexpressing transgenic (MT‐TG) mice. The present study was undertaken to define whether diabetes can induce endoplasmic reticulum (ER) stress and MT prevent attenuating ER stress. Diabetes induced streptozotocin both MT‐TG wild‐type (WT) Two weeks, 2 5 months after onset, detected expression chaperones, apoptosis...
Peripheral and integral membrane proteins can be located in several different subcellular compartments, it is often necessary to determine the location of such or track their movement living cells. Image-based colocalization labeled compartment markers frequently used for this purpose, but method limited terms throughput resolution. Here we show that bioluminescence resonance energy transfer (BRET) between interest compartment-targeted BRET partners report live The sensitivity sufficient...
Iodine vacancies and uncoordinated Pb0 defects existing at the perovskite surface have been widely demonstrated to induce deep-level defects, which can greatly limit improvement of efficiency stability solar cells (PSCs). In this work, a novel strategy is proposed for functionalizing by using trimethylsulfoxonium iodide (TMSI), enhance defect formation energy inhibit defects. Meanwhile, TMSI modification also fill iodine surface-terminating ends. Consequently, optimized device shows improved...
The inefficient conversion of lead iodide to perovskite has become one the major challenges in further improving performance solar cells fabricated by two-step method. Herein, discontinuous layer realized introduction a polyfluorinated organic diammonium salt, octafluoro-([1,1'-biphenyl]-4,4'-diyl)-dimethanaminium (OFPP) which does not form low-dimensional perovskites, can enable satisfactory into perovskite, leading meliorated crystallinity and enlarged grains OFPP modulated (OFPP-PVK)...
Abstract Bioluminescence resonance energy transfer (BRET) is often used to study association of membrane proteins and in particular oligomerization G protein-coupled receptors (GPCRs). Oligomerization class A GPCRs controversial, part because the methods this question are not completely understood. Here we reconsider β 2 adrenergic receptor (β AR) reevaluate BRET titration as a method protein association. Using inducible expression acceptor at multiple levels donor find that between AR...
Initial attachment plays an important role in biofilm formation wastewater treatment processes. However, the initial process mediated by N-acyl-homoserine lactones (AHLs) is difficult to be fully understood due lack of non-invasive and on-line investigation techniques. In this study, AHL-regulated was quantified using ultrasonic time-domain reflectometry (UTDR) as in-situ monitoring technique. Results demonstrated that reversible adhesion time municipal industrial wastewaters significantly...
ABSTRACT RIG-I and MDA5, known as the RIG-I-like receptors (RLRs), play a pivotal role in inducing antiviral responses to RNA viral infections. While chickens lack RIG-I, they possess functionally enhanced MDA5 that recognizes pathogens regulates immunity, underscoring critical of maintaining immune homeostasis chickens. However, precise mechanisms governing expression optimal activation remain unclear. Here, we reveal chicken E3 ubiquitin ligase RNF20 is essential for modulating...
Abstract Bats are natural hosts for various highly pathogenic viruses, which pose a considerable threat to humans and animals. However, they rarely display signs of disease infection from these viruses. The expression IRF7-induced IFN-β plays crucial role in preventing viral infections. the bat IRF7 during remains unclear. In this study, we cloned Tadarida brasiliensis discovered that its amino acid sequence was poorly conserved among species. Next, investigated mRNA lung cells (TB 1 Lu)...
Abstract Obesity often leads to obesity‐related cardiac hypertrophy ( ORCH ), which is suppressed by zinc‐induced inactivation of p38 mitogen‐activated protein kinase (p38 MAPK ). In this study, we investigated the mechanisms zinc inactivates prevent . Mice (4‐week old) were fed either high fat diet HFD , 60% kcal fat) or normal ND 10% containing variable amounts (deficiency, and supplement) for 3 6 months. P38 si RNA inhibitor SB 203580 used suppress activity in vitro vivo respectively....
Abstract Although organic small molecule spiro‐OMeTAD is widely used as a hole‐transport material in perovskite solar cells, its limited electric conductivity poses bottleneck the efficiency improvement of cells. Here, low‐cost and easy‐fabrication technique developed to enhance hole‐extraction ability by doping it with commercially available benzoyl peroxide (BPO). The experimental results show that increases several orders magnitude, from 6.2×10 −6 S cm −1 for pristine 1.1×10 −3 at 5 % BPO...