- Chronic Kidney Disease and Diabetes
- Clinical Nutrition and Gastroenterology
- Renal cell carcinoma treatment
- Childhood Cancer Survivors' Quality of Life
- Child Nutrition and Feeding Issues
- Diet and metabolism studies
- Sepsis Diagnosis and Treatment
- Genital Health and Disease
- Nutrition and Health in Aging
- Nonmelanoma Skin Cancer Studies
- Immunodeficiency and Autoimmune Disorders
- Renal and related cancers
- Prostate Cancer Treatment and Research
- T-cell and B-cell Immunology
- Birth, Development, and Health
- Urologic and reproductive health conditions
- COVID-19 Clinical Research Studies
- Renal and Vascular Pathologies
- Polyomavirus and related diseases
- Renal Diseases and Glomerulopathies
- Organ Donation and Transplantation
- Cancer and Skin Lesions
- Blood groups and transfusion
- MRI in cancer diagnosis
- Renal Transplantation Outcomes and Treatments
Boston Medical Center
2023
University Medical Center
2023
Boston University
2023
Mayo Clinic
2020-2021
Mayo Clinic in Arizona
2020-2021
Hypertension Institute
2019
To compare coronavirus disease 2019 (COVID-19) acute kidney injury (AKI) to sepsis-AKI (S-AKI). The morphology and transcriptomic proteomic characteristics of autopsy kidneys were analyzed.Individuals 18 years age older who died from COVID-19 had an performed at Mayo Clinic between April 2020 October included. Morphological evaluation the 17 individuals with was performed. In a subset seven cases postmortem interval less than or equal 20 hours, ultrastructural molecular (targeted...
Age, CKD risk factors, and kidney function are associated with larger glomerular volume a higher percentage of globally sclerotic glomeruli. Knowledge how these associations may differ by cortical depth is limited.To investigate glomerulosclerosis across different depths cortex, we studied wedge sections the renal parenchyma from 812 patients who underwent radical nephrectomy (for tumor), separately characterizing glomeruli in superficial (subcapsular), middle, deep (juxtamedullary) regions....
Nephron hypertrophy and nephrosclerosis may be important determinants of CKD mortality. However, studies outcomes associated with these microstructural features have been limited to small tissue specimens from patients selected for either good kidney health or known disease.To determine whether are predictive progressive mortality outcomes, we studied who underwent a radical nephrectomy tumor. Large wedge sections renal parenchyma distal the tumor were stained scanned into high-resolution...
Significance Statement A higher percentage of the kidney cortex area that exhibits interstitial fibrosis/tubular atrophy (IF/TA) is a feature poor prognosis on biopsy. This study describes IF/TA density (the number foci per cortex) and shows it predicts progressive CKD, independent both clinical characteristics among patients who have undergone nephrectomy. Other patterns inflammation were not predictive for CKD mortality beyond characteristics. At same IF/TA, suggests more scattered...
Home enteral nutrition (HEN) use continues to increase in children unable meet nutritional needs through oral intake. Some patients do not tolerate standard polymeric formula (SPF), which may lead malnutrition. Use of peptide-based diet (PBD) has demonstrated benefits adults, however there remains a paucity data pediatric population.Retrospective review medical records receiving HEN between October 2015 and 2019 was conducted. Nutrition, tolerance, healthcare utilization tracked May 2020....
Introduction: The prevalence of home enteral nutrition (HEN) has increased dramatically as studies showing clinical benefit have emerged. During this time, the practice HEN evolved well including availability diverse formulas ranging in macronutrient distribution and concentration. Despite availability, there continues to be a paucity data regarding efficacy 2.0 kcal/ml density population.Materials Methods: A retrospective review database was conducted for use concentrated formula (2.0...
The Histocompatibility and Identity Testing Committee offers an overview of the College American Pathologists’ (CAP) Proficiency (PT) program, commemorating its significant 75th anniversary in 2024. CAP PT program has undergone growth evolution over years, ultimately achieving Centers for Medicare Medicaid Services approval. In 1979, CAP’s partnership with Association Clinical marked a pivotal moment, leading to creation first proficiency testing survey 1980. This laid foundation various...