- Colorectal Cancer Screening and Detection
- Dental Health and Care Utilization
- Gastric Cancer Management and Outcomes
- Global Cancer Incidence and Screening
- Primary Care and Health Outcomes
- Health Sciences Research and Education
- Pharmaceutical Practices and Patient Outcomes
- Innovations in Medical Education
- Diverticular Disease and Complications
- Diabetes Management and Education
- Palliative Care and End-of-Life Issues
- Chronic Disease Management Strategies
- Virus-based gene therapy research
- Microscopic Colitis
- Viral Infectious Diseases and Gene Expression in Insects
- Cleft Lip and Palate Research
- Dental Research and COVID-19
- Medication Adherence and Compliance
- Fluoride Effects and Removal
- Genetic factors in colorectal cancer
- Gastrointestinal disorders and treatments
- Bone health and osteoporosis research
- Health Policy Implementation Science
- Cervical Cancer and HPV Research
- Mycobacterium research and diagnosis
University of Iowa
2015-2024
University of Massachusetts Chan Medical School
1994-2024
University of Iowa Holden Comprehensive Cancer Center
2024
Research Network (United States)
2015-2020
Oregon Health & Science University
2019-2020
University of Iowa Hospitals and Clinics
2020
Oregon Clinic
2019
Mercy Medical Center
2015
Iowa City VA Health Care System
2015
Mayo Clinic in Arizona
2015
<h3>Abstract</h3> <b>Objectives:</b> To characterise the information needs of family doctors by collecting questions they asked about patient care during consultations and to classify these in ways that would be useful developers knowledge bases. <b>Design:</b> Observational study which investigators visited for two half days collected their questions. Taxonomies were developed clinical topic generic type sought each question. <b>Setting:</b> Eastern Iowa. <b>Participants:</b> Random sample...
During the past decade, a variety of instrument-assisted bacterial identification and antimicrobial susceptibility test systems have been developed which permit provision results in matter hours rather than days, as has case with traditional overnight procedures. These newer rapid techniques are much more expensive older methods. It presumed but not proven that clinical benefits testing to patients infection offset added cost. The intent this study was objectively define impact testing. A...
OBJECTIVE: The available data on antidepressant levels in nursing infants were analyzed order to calculate average infant drug and determine what factors influence plasma breast-feeding of mothers treated with antidepressants. METHOD: Electronic searches MEDLINE, PreMEDLINE, Current Contents, Biological Abstracts, PsycINFO from 1966 through July 2002 followed by bibliographic identified 67 relevant studies (two unpublished). By consensus the authors 57 maternal plasma, breast milk, and/or...
<i>Objectives:</i> Patient self-care behaviors, including taking medication, following a meal plan, exercising regularly, and testing blood glucose, influence diabetes control. The purpose of this research was to identify (1) which barriers management are associated with problem behaviors (2) patient <i>Methods:</i> This cross-sectional study linked medical record self-reported information from patients type 2 diabetes. A randomly selected sample 800 clinic mailed an investigator-developed...
Purpose To examine the impact of a personal health record (PHR) on medication-use safety among older adults.
Thirty-three survivors of childhood cancer were tested with event-related potentials (P300), motor reaction time tests, and neuropsychological tests to assess the underlying physiological basis treatment-related cognitive sequelae. Thirteen patients had received intrathecal chemotherapy, 11 chemotherapy plus cranial radiotherapy, nine been treated without any form central nervous system therapy. Neuropsychological performance groups radiotherapy was normal, but group given significantly...
Only about half of all eligible Americans have been screened for colorectal cancer (CRC). The objective this study was to test whether mailed educational materials and a fecal immunochemical (FIT), with or without scripted telephone reminder, led FIT testing. In addition, we compared changes in attitudes toward, readiness for, barriers screening from baseline follow-up after education screening.Subjects due CRC were recruited 16 Iowa Research Network family physician offices. Half the...
<h3>Background:</h3> Many adults have not been screened for colon cancer, a potentially preventable cause of death. <h3>Methods:</h3> This was randomized controlled trial conducted between December 2008 and April 2011 to improve CRC screening in 16 rural family physician offices. Subjects due were within each practice 1 4 groups: (1) usual care; (2) chart reminder; (3) reminder, mailed education, reminder magnet, fecal immunochemical test (FIT) (mailed education/FIT); or (4) all the...
Introduction Low back pain (LBP) is a key source of medical costs and disability, impacting over 31 million Americans at any given time resulting in US$100–US$200 billion per year total healthcare costs. LBP one the leading causes ambulatory care visits to US physicians; problematically, these often result treatments such as opioids, surgery or advanced imaging that can lead more harm than benefit. The American College Physicians (ACP) Guideline for Back Pain recommends patients receive...
Less than half of eligible Americans have been screened for colorectal cancer (CRC). The objective this study was to describe physicians' reasons screening or not specific patients CRC and their approach testing discussions.This used mixed-methods. Physicians described 6 randomly chosen who were (3 3 screened) whose status ascertained by medical record review. Verbatim transcripts from physicians responding structured interview questions identify themes. Specific elements discussion examined...
Background: The use of clinical pharmacists in primary care has improved the control several chronic cardiovascular conditions. However, many private physician practices lack resources to implement team-based with pharmacists. purpose this study was evaluate whether a centralized, remote, pharmacy service could improve guideline adherence and secondary measures risk offices rural small communities. Methods Results: This prospective trial 12 family medicine cluster randomized either...
<h3>Background:</h3> Little is known about the burden of atopic dermatitis (AD) encountered in US primary care practices and frequency type skin routinely used children. <h3>Objective:</h3> To estimate prevalence AD children 0 to 5 years attending United States describe routine this population. <h3>Design:</h3> A cross-sectional survey study a convenience sample under age for any reason. <h3>Setting:</h3> Ten states. <h3>Results:</h3> Among 652 practices, estimated ever having was 24% (95%...
Young children need increased access to dental prevention and care. Targeting high caries risk first helps meet this need. The objective of study was develop a parent-completed, easy-to-score, short, accurate tool for screening in primary health care settings identify at cavities. A longitudinal, prospective, multisite, cohort enrolled (primarily through settings) followed 985 (out 1,326) 1-y-old their caregivers (PCGs) until age 4. PCG completed 52-item self-administered questionnaire, were...
Despite widespread use of fecal immunochemical tests (FITs) for colorectal cancer (CRC) screening, data to guide test selection are limited.
Di(adenosine-5')oligophosphate nucleotides of general structure ApnA (n = 2-6) inhibited phosphorylation immunoglobulin G from tumor-bearing rabbits (TBR IgG) by pp60src protein kinase purified Rous sarcoma virus-transformed rat tumor cells. Ap4A, a nucleotide associated with eukaryotic cell proliferation, was one the most effective inhibitors in series, causing 50% inhibition TBR IgG at 15 microM. Ap4A pp60src-dependent solution and immunoprecipitates, as well tubulin,...