A5100345748- Plant Gene Expression Analysis
- Photosynthetic Processes and Mechanisms
- RNA modifications and cancer
- Seed and Plant Biochemistry
- Muscle Physiology and Disorders
- Plant Physiology and Cultivation Studies
- Ubiquitin and proteasome pathways
- Neurogenetic and Muscular Disorders Research
- Peptidase Inhibition and Analysis
- Horticultural and Viticultural Research
- Chemical Synthesis and Analysis
- Vitamin C and Antioxidants Research
- Alcohol Consumption and Health Effects
- Carbon and Quantum Dots Applications
- Heat shock proteins research
- Signaling Pathways in Disease
- GABA and Rice Research
- Genetic Mapping and Diversity in Plants and Animals
- RNA regulation and disease
- Biopolymer Synthesis and Applications
- Statistical Methods and Inference
- Glycosylation and Glycoproteins Research
- Sexual Differentiation and Disorders
- Synthesis of β-Lactam Compounds
- Geomagnetism and Paleomagnetism Studies
Shandong Agricultural University
2023
Peking University Shenzhen Hospital
2022-2023
Guangdong Ocean University
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
University of South China
2022
Sichuan Academy of Agricultural Sciences
2022
Xiangya Hospital Central South University
2022
Central South University
2022
Jiangxi Agricultural University
2022
Beijing University of Agriculture
2021
Anthocyanin pigments contribute to plant coloration and are valuable sources of antioxidants in the human diet as components fruits vegetables. Their production is known be induced by light apple fruit (Malus domestica); however, underlying molecular mechanism responsible for early-stage light-induced anthocyanin biosynthesis remains unclear. Here, we identified an ethylene response factor (ERF) protein, ERF109, involved found that it promotes directly binding anthocyanin-related gene...
We aimed to investigate the effects of dietary alpha-lipoic acid (α-LA) on growth performance, serum biochemical indexes, liver morphology, antioxidant capacity, and transcriptome juvenile hybrid groupers (Epinephelus fuscoguttatus♀ × Epinephelus polyphekadion♂). Four experimental diets supplemented with 0 (SL0), 0.4 (L1), 0.6 (L2), 1.2 (L3) g/kg α-LA were formulated fed three replicates grouper (24.06 ± 0.15 g) for 56 d. The results indicated that significantly decreased weight gain rate in...
The 12-oxophytoeienoic acid reductase (OPR) is a kind of enzyme in the octadecanoid biosynthesis pathway that determines jasmonic acid. Although roles OPRs have been extensively studied several crop plants, little known about biological functions OPR-encoding genes Capsicum annuum plants. In this study, seven OPR family (CaOPR1-7) were identified from C. genome. physical and chemical properties CaOPR1-7 further analyzed, including gene expression patterns, promoter elements, chromosomal...
Background To offer 4‐year clinical prenatal diagnosis experience of Duchenne muscular dystrophy ( DMD ). Methods Denaturing high‐performance liquid chromatography DHPLC ) and Sanger sequencing were used for molecular 237 families. Results In the study, deletions, duplications, complex rearrangement small mutations accounted 47.3%, 8.4%, 1.7% 42.6% families, respectively. Sixty‐six different deletion patterns identified in 112 Fourteen duplication 20 families 4 rearrangements identified....
A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was established to quantify sialic acid (N-acetylneuraminic acid, NANA) from lipoproteins and human plasma. The used investigate the different contents of NANA between diabetic with an average age 51.6 years healthy participants 50.7 years. lipoprotein samples hydrolyzed by acetic (pH = 2) at 80 °C for 2 h analyzed optimized LC-MS/MS after high speed centrifugation filtration. limits detection quantification were 7.4 24.5 pg,...
In this article, we propose a family of flexible shrinkage estimators which can use geometric or arithmetic means sample variances all genes as the target statistic for and also allow non-normal distribution data. The optimal parameters are derived under squared log error loss function estimated by consistent general asymptotic framework. proposed were evaluated through series Monte-Carlo simulation studies applied to real data from gene expression study leukemia patients.
Tris-(2, 3-dibromopropyl) isocyanurate (TBC) is a heterocyclic hexabrominated additive flame retardant, which bio-accumulative, and can cause reproductive, endocrine disrupting, neurotoxic effects. The present study was aimed at further evaluating the oxidative stress induced by TBC in human neuronal cells rat brains. results demonstrated that caused apop-tosis of U251 SH-SY5Y dose-and time-dependent manner were more sensitive to than cells. Meanwhile, 1 μg/mL significantly in-duce...
To optimize the methods for genetic detection and prenatal diagnosis of Duchenne muscular dystrophy (DMD).Denaturing high-performance liquid chromatography (DHPLC), multiplex PCR (mPCR), sequencing other molecular techniques were used in combination 8 cases diagnosed as DMD.Among cases, 4 have carried large deletions, 3 point mutations, among which 6 de novo type. Prenatal offered 5 families, results showed that none fetuses had deletions or mutations. The pregnancies continued healthy...
Enzymatic browning of fresh-cut apples causes a decline in sensory quality, reduction commodity value, and economic losses. In the present study, application 2.0 % Lys 1.0 Arg (1:1, v/v) combined solution was shown to inhibit apple browning. particular, Lys/Arg treatment impeded weight loss, while preserving firmness, soluble solid content, polyphenol oxidase (PPO) activity, total phenolic contents. Moreover, contents ten compounds showed variable trends, with ferulic acid notably inhibiting...
Abstract Tartary buckwheat is rich in flavonoids, which not only play an important role plant-environment interaction, but are also beneficial to human health. Rutin a therapeutic flavonol massively accumulated buckwheat. It has been demonstrated that transcription factors control rutin biosynthesis. However, the transcriptional regulatory network of fully clear. In this study, through transcriptome and target metabolomics, we validated FtMYB102 FtbHLH4 TFs at different developmental stages...
Abstract Aberrant SUMOylation contributes to the progression of hepatocellular carcinoma (HCC), yet molecular mechanisms have not been well elucidated. RNF146 is a key regulator Wnt/β-catenin signaling pathway, which frequently hyperactivated in HCC. Here, it identified that can be modified by SUMO3. By mutating all lysines RNF146, we found K19, K61, K174 and K175 are major sites for SUMOylation. UBC9/PIAS3/MMS21 SENP1/2/6 mediated conjugation deconjugation SUMO3, respectively. Furthermore,...