A5035703792- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Adipose Tissue and Metabolism
- Assisted Reproductive Technology and Twin Pregnancy
- Epigenetics and DNA Methylation
- Regulation of Appetite and Obesity
- Traumatic Brain Injury Research
- Prenatal Screening and Diagnostics
- Reproductive Biology and Fertility
- Stroke Rehabilitation and Recovery
- Mobile Health and mHealth Applications
- Botulinum Toxin and Related Neurological Disorders
- Child and Adolescent Psychosocial and Emotional Development
- Reproductive Physiology in Livestock
- Psychosocial Factors Impacting Youth
- Optimism, Hope, and Well-being
- Sperm and Testicular Function
- Vaccine Coverage and Hesitancy
- HIV/AIDS Research and Interventions
- Neurological disorders and treatments
- Gestational Diabetes Research and Management
- Adolescent and Pediatric Healthcare
- Parkinson's Disease Mechanisms and Treatments
- Cervical Cancer and HPV Research
- Hepatitis B Virus Studies
University of Pennsylvania
2018-2025
Winship Cancer Institute
2024
Emory University
2019-2024
Cancer Institute (WIA)
2024
National Institute of Nursing Research
2024
National Institutes of Health
2024
California University of Pennsylvania
2021
Translational Therapeutics (United States)
2019
University of Illinois Chicago
2015-2017
In vitro fertilization (IVF) is a non-coital method of conception used to treat human infertility. Although IVF viewed as largely safe, it associated with adverse outcomes in the fetus, placenta, and adult offspring. Because studies focusing on effect male reproductive system are limited, we mouse model assess morphological molecular effects We evaluated three developmental stages: 18.5-day fetuses 12- 39-week-old adults. Regardless age, observed changes testicular-to-body weight ratios,...
ABSTRACT Although widely used, assisted reproductive technologies (ARTs) are associated with adverse perinatal outcomes. To elucidate their underlying causes, we have conducted a longitudinal analysis of placental development and fetal growth using mouse model to investigate the effects individual ART procedures: hormone stimulation, in vitro fertilization (IVF), embryo culture transfer. We demonstrate that transfer blastocysts naturally conceived without stimulation developed vivo prior can...
Abstract Although in vitro fertilization (IVF) is associated with adverse perinatal outcomes, there increasing concern about the long‐term and sex‐specific health implications. Augmenting our IVF mouse model to longitudinally investigate metabolic outcomes offspring from optimal neonatal litter sizes, we found offspring. IVF‐conceived females had higher body weight cholesterol levels compared naturally conceived females, whereas males of triglycerides insulin, increased fat composition....
Fatigue is a highly prevalent symptom for individuals with polycystic ovary syndrome (PCOS); however, characterization of fatigue and investigation into the gut microbiome-a pathway that may contribute to fatigue-remains inadequately explored in Black women PCOS.
Background When the COVID-19 pandemic hit in 2020, researchers P30 Center for Study of Symptom Science, Metabolomics, and Multiple Chronic Conditions at Emory University’s Nell Hodgson Woodruff School Nursing faced major challenges recruitment data collection because limited access to clinic community facilities risk exposure associated with in-person study contact. Objectives The purpose this article is (a) describe how a cadre pilot/supplement principal investigators adapted their studies...
As a part of Korea's smoking cessation policy, the price tobacco was increased in January 2015. Initially, rate among adolescents began to decrease. The current data, however, show that adolescent is on rise. Alongside policies, there need further understand additional preventive measures promote successful by identifying factors influence maintenance adolescents. This study aimed identify after attempting increase price. used large-scale, nationwide, secondary data obtained from Korean...
Abstract Accumulating evidence suggests that dysregulation of placental DNA methylation (DNAm) is a mechanism linking maternal weight during pregnancy to metabolic programming outcomes. The common marmoset, Callithrix jaccus , platyrrhine primate species has provided much insight into studies the placenta, condition, and programming, yet relationships between DNAm are unknown. Here, we report genome‐wide from term marmoset placentas using reduced representation bisulfite sequencing. We...
BACKGROUND: Progressive Supranuclear Palsy (PSP) is an incurable neurodegenerative disorder. One variant of PSP a frontal lobe cognitive or behavioral presentation (PSP-F). Currently, the primary management this disease rooted in neurological rehabilitation, therefore, early, and accurate diagnosis key. CASE REPORT: Here we present 60-year-old man with 2–3-year history functional decline changes. He was misdiagnosed late-onset psychiatric During his second inpatient admission, full workup...
Abstract In vitro fertilization (IVF) is a non-coital method of conception used to treat human infertility. Although IVF viewed as largely safe, it associated with adverse outcomes in the fetus, placenta, and adult offspring life. Because studies focusing on effect male reproductive system are limited, we mouse model assess morphological molecular effects offspring. We evaluated three developmental stages: 18.5-day fetuses 12- 39-week-old adults. Regardless age, observed changes...
Abstract Although in vitro fertilization (IVF) is associated with adverse perinatal outcomes, an increasing concern the long-term health implications. We augmented our IVF mouse model to longitudinally investigate cardiometabolic outcomes offspring from optimal neonatal litter sizes. found that IVF-conceived females had higher body weight and cholesterol levels compared naturally-conceived females, whereas males of triglycerides insulin, increased fat composition. Through transcriptomics...
Abstract Background Professional boxers and Mixed Martial Arts (MMA) fighters regularly sustain blunt force trauma to the head leading Traumatic Brain Injury (TBI) concussion; therefore, are at high risk for chronic traumatic encephalopathy neurodegenerative disease. Family history of dementia (fhD) may significantly modulate fighter response TBI. Genetic polymorphisms associated with have been reported an individual’s brain injury influence emotionality, risk‐taking, cognition. A recent...