Fang Li

ORCID: 0000-0002-3342-9394
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About
Contact & Profiles
Research Areas
  • Hair Growth and Disorders
  • Cancer-related molecular mechanisms research
  • Photosynthetic Processes and Mechanisms
  • Skin and Cellular Biology Research
  • Plant Stress Responses and Tolerance
  • Plant Molecular Biology Research
  • IgG4-Related and Inflammatory Diseases
  • Kruppel-like factors research
  • Plant Physiology and Cultivation Studies
  • Helicobacter pylori-related gastroenterology studies
  • Wound Healing and Treatments
  • T-cell and Retrovirus Studies
  • Medical Imaging and Analysis
  • melanin and skin pigmentation
  • Plant Reproductive Biology
  • Postharvest Quality and Shelf Life Management
  • Periodontal Regeneration and Treatments
  • Neuroendocrine Tumor Research Advances
  • IL-33, ST2, and ILC Pathways
  • RNA Research and Splicing
  • Gastrointestinal motility and disorders
  • Reconstructive Surgery and Microvascular Techniques
  • Spine and Intervertebral Disc Pathology
  • Plant Micronutrient Interactions and Effects
  • Ion Channels and Receptors

Chongqing University
2025

Northwest A&F University
2016-2023

Hybrid Rapeseed Research Center of Shaanxi Province
2022

Guangdong University Of Finances and Economics
2021

Guangdong University of Finance
2021

Baogang Group (China)
2021

Peking Union Medical College Hospital
2020

Chinese Academy of Medical Sciences & Peking Union Medical College
2020

Stony Brook University
2017

IgG4-related disease (RD) is characterized by lymphoplasmacytic infiltration enriched in IgG4-positive plasma cells and variable degrees of fibrosis with a characteristic storiform pattern. Since an important feature IgG4-RD, we performed prospective cohort study to evaluate the performance <sup>68</sup>Ga-fibroblast activation protein inhibitor (FAPI), recently introduced PET agent targeting fibroblast protein, IgG4-RD. <b>Methods:</b> Twenty-six patients IgG4-RD were recruited. All...

10.2967/jnumed.120.244723 article EN Journal of Nuclear Medicine 2020-06-08

Polygalacturonase (PG) is an important hydrolytic enzyme involved in pectin degradation during fruit softening. However, the roles of

10.3390/ijms17111933 article EN International Journal of Molecular Sciences 2016-11-18

Abstract Cashmere, also known as soft gold, is produced from the secondary hair follicles (SHFs) of cashmere goats. The number SHFs determines yield and quality cashmere; therefore, it interest to investigate transcriptional profiles present during goat follicle development. However, mechanisms underlying this development process remain largely unexplored, studies regarding mostly use a murine research model. In study, provide comprehensive understanding cellular heterogeneity cell fate...

10.1016/j.gpb.2021.07.003 article EN cc-by-nc-nd Genomics Proteomics & Bioinformatics 2021-06-01

The leucine-rich repeat receptor-like protein kinase (LRR-RLK) family represents the largest group of RLKs in plants and plays vital roles plant growth, development responses to environmental stress. Although LRR-RLK families have been identified many species, they not yet reported B. napus. In this study, a total 444 BnLRR-RLK genes were genome Brassica napus cultivar "Zhongshuang 11" (ZS11), classified into 22 subfamilies based on phylogenetic relationships genome-wide analyses. Conserved...

10.3389/fpls.2022.865132 article EN cc-by Frontiers in Plant Science 2022-04-12

Cashmere is initiated and develops in the fetal stages number density of secondary hair follicles (SHFs) determine cashmere production quality. Growing evidence indicates that both microRNA (miRNA) long non-coding RNA (lncRNA) play an indispensable role follicle (HF) growth development. However, little known about miRNAs, lncRNAs, their functions as well interactions during initiation Here, based on lncRNA miRNA high-throughput sequencing bioinformatics analysis, we identified 10,485 40,639...

10.3390/ijms231710006 article EN International Journal of Molecular Sciences 2022-09-02

Long noncoding RNAs (lncRNAs) have an essential role in mammary gland development and lactation. Our earlier study showed that the lncRNA proliferation fatty acid synthesis-associated transcript (MPFAST) is highly expressed Holstein cow during middle lactation period compared to dry period, which indicates its potential Therefore, gain- loss-of-function experiments were performed on bovine epithelial cells (BMECs) by cell counting kit 8 (CCK8), 5-ethynyl-2'-deoxyuridine (EdU), real-time...

10.1021/acs.jafc.2c04789 article EN Journal of Agricultural and Food Chemistry 2022-09-16

Highlights•Acer1 is a skin-specific ceramidase that controls the catabolism of ceramides•Acer1 plays key role in homeostasis epidermis and its appendages•Acer1−/− mice suffer from progressive alopecia•Loss Acer1 progressively depletes population hair follicle stem cellsSummaryCeramides their metabolites are important for epidermis, but much remains unknown about roles specific pathways ceramide metabolism skin biology. With mouse model deficient alkaline (Acer1) gene, we demonstrate ACER1...

10.1016/j.stemcr.2017.09.015 article EN cc-by-nc-nd Stem Cell Reports 2017-10-19

The cytochrome P450 (CYP450) monooxygenase superfamily, which is involved in the biosynthesis pathways of many primary and secondary metabolites, plays prominent roles plant growth development. However, systemic information about CYP450s

10.3390/plants12020365 article EN cc-by Plants 2023-01-12

Abstract Background During goat embryonic morphogenesis and postnatal initiation of hair follicle (HF) regeneration, dermal papilla (DP) cells play a vital role in formation. Growing evidence shows that microRNAs (miRNAs) participate HF development DP cell proliferation. However, the molecular mechanisms have not been thoroughly investigated. Result In this study, we utilized miRNA sequencing (miRNA-Seq) to identify differentially expressed miRNAs at different cycling stages (anagen...

10.1186/s12864-020-06799-1 article EN cc-by BMC Genomics 2020-06-26

Abstract Cashmere, also known as soft gold, is produced from the secondary hair follicles in Cashmere goats and it’s therefore of significance to investigate molecular profiles during goat follicle development. However, our current understanding machinery underlying remains largely unexplored researches regarding development mainly used mouse a research model. To provides comprehensively on cellular heterogeneity cell lineage fate decisions, we performed single-cell RNA sequencing 19,705...

10.1101/2020.01.30.926287 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-01-31

Abstract DNA methylation plays a critical role in early embryonic skin development by controlling gene expression. Act as an indirect regulator, long non-coding RNA (lncRNA) recruit methyltransferases to specific genomic sites methylate DNA. However, the molecular regulation mechanisms underlying hair follicle morphogenesis is unclear cashmere goat. In this study, RNA-seq and Whole-genome bisulfite sequencing (WGBS) day 65 (E65) E120 tissues of goat were used reveal complex regulatory...

10.1101/2020.01.30.926360 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-01-31

Objective: To observe the effects of platelet-rich plasma (PRP) on in vitro proliferation and migration fibroblasts from human chronic refractory wound granulation tissue.Methods: Fibroblasts were separated tissue then identified. The obtained divided into fetal bovine serum (FBS) group, hydrogel group PRP three groups cultured with culture mediums containing FBS, respectively, order to growth fibroblasts. scratch assay was used fibroblasts.Results: had more than FBS since Day 5 culture,...

10.5430/dcc.v8n1p24 article EN Discussion of Clinical Cases 2021-08-18
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