Huanhuan Du

ORCID: 0000-0002-3382-4212
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About
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Research Areas
  • Supercapacitor Materials and Fabrication
  • Advanced Drug Delivery Systems
  • Nanoporous metals and alloys
  • Drug Solubulity and Delivery Systems
  • Ionic liquids properties and applications
  • Carbon Nanotubes in Composites
  • Luminescence Properties of Advanced Materials
  • Electrochemical Analysis and Applications
  • Advanced Sensor and Energy Harvesting Materials
  • Molecular Sensors and Ion Detection
  • Graphene research and applications
  • Advancements in Battery Materials
  • Phytochemical compounds biological activities
  • Semiconductor materials and devices
  • Nanomaterials for catalytic reactions
  • Electrocatalysts for Energy Conversion
  • MXene and MAX Phase Materials
  • Sulfur Compounds in Biology
  • Lanthanide and Transition Metal Complexes
  • Natural product bioactivities and synthesis
  • Nanocluster Synthesis and Applications
  • Molecular Junctions and Nanostructures
  • Ginseng Biological Effects and Applications
  • Advanced Electron Microscopy Techniques and Applications
  • Redox biology and oxidative stress

Huazhong University of Science and Technology
2020-2024

Soochow University
2019-2024

Kunming University of Science and Technology
2020-2023

Minzu University of China
2021-2022

Inner Mongolia University
2021

Beijing Technology and Business University
2019-2020

Inner Mongolia University for Nationalities
2020

Anhui Science and Technology University
2019

Anhui University of Science and Technology
2019

Beihang University
2016-2018

The combination of gene therapy and chemotherapy has recently received considerable attention for cancer treatment. However, low transfection efficiency poor endosomal escape genes from nanocarriers strongly limit the success clinical use small interfering RNA (siRNA). In this study, a novel pH-responsive, surface-modified single-walled carbon nanotube (SWCNT) was designed codelivery doxorubicin (DOX) survivin siRNA. Polyethylenimine (PEI) covalently conjugated with betaine, resulting...

10.1021/acsami.8b20810 article EN ACS Applied Materials & Interfaces 2019-02-18

The large-scale fabrication of high-performance on-chip micro-supercapacitors (MSCs) is the footstone for development next-generation miniaturized electronic devices. In practical applications, however, MSCs may suffer from a low areal energy density as well complicated strategy that incompatible with semiconductor processing technology. Herein, we propose scalable realization silicon-based three-dimensional (3D) all-solid-state MSC via combination semiconductor-based electrode processing,...

10.1021/acsami.0c14441 article EN ACS Applied Materials & Interfaces 2020-09-09

Bakuchiol, a prenylated phenolic monoterpene derived from the fruit of Psoralen corylifolia L. (Buguzhi), is widely used to treat tumors, viruses, inflammation, and bacterial infections. In this study, we designed synthesized 30 bakuchiol derivatives identify new anti-inflammatory drugs. The activities were screened using lipopolysaccharide-induced RAW264.7 cells. To evaluate activity compounds, measured nitric oxide (NO), interleukin-6, tumor necrosis factor-α production. Based on screening...

10.1021/acs.jnatprod.1c00377 article EN Journal of Natural Products 2022-01-08

Significant amounts of ammonia, nitric acid and hydrochloric as ammonium particle precursors have been found in urban polluted air. In order to advance understanding the formation dissociation nitrate chloride, an on-line analyzer for monitoring aerosols gases ambient air was employed measure concentrations sulfate, chloride well related gaseous at one hour resolution. The highest levels summed hourly-averaged nitrate, reached up 177.7 μg/m3 PM10 from 12 14 June, 101.2 PM2.5 1 3 July, 2009...

10.4209/aaqr.2010.04.0034 article EN cc-by Aerosol and Air Quality Research 2010-01-01

Purpose: Novel collagenase IV (ColIV) and clusterin (CLU)-modified polycaprolactone-polyethylene glycol (PCL-PEG) nanoparticles that load doxorubicin (DOX) were designed fully evaluated in vitro vivo. Methods: PCL-PEG-ColIV was synthesized by linking PCL-PEG ColIV through a carbodiimide method. DOX-loaded (DOX-PCL-PEG-ColIV) self-assembly prepared, followed noncovalently adsorbing CLU on the DOX-PCL-PEG-ColIV surface to obtain /CLU nanoparticles, which can penetrate tumor extracellular...

10.7150/thno.47446 article EN cc-by Theranostics 2020-11-06

The gate-type carbon nanotubes cathodes exhibit advantages in long-term stable emission owing to the uniformity of electrical field on nanotubes, but gate inevitably reduces transmittance electron beam, posing challenges for system stabilities. In this work, we introduce beam focusing technique using self-charging SiNx/Au/Si gate. potential SiNx is measured be approximately -60 V quickly after cathode turning on, negative can maintained as goes on. charged surface generates rebounding...

10.1038/s41467-024-45142-0 article EN cc-by Nature Communications 2024-01-26

In this work, we present the fabrication of highly luminescent carbon dots (CDs) by a double passivation method with assistance Ca(OH)2. reaction process, Ca2+ protects active functional groups from overconsumption during dehydration and carbonization, electron-withdrawing on CD surface are converted to electron-donating hydroxyl ions. As result, fluorescence quantum yield CDs was found increase increasing Ca(OH)2 content in process. A blue-shift optical spectrum also content, which could be...

10.3390/nano7070176 article EN cc-by Nanomaterials 2017-07-07

In this study, limonin derivatives were used to design new anti-inflammatory compounds with high pharmacological activity and low toxicity. A total of 23 discovered, synthesized, screened for their against lipopolysaccharide (LPS)-treated RAW 264.7 cells. Of them, compound f4 was found be the most active, a higher efficiency compared celecoxib. Subsequently, we studied mechanism underlying that it inhibited proinflammatory cytokines by blocking NF-κB/MAPK signaling pathway in LPS-treated...

10.1021/acs.jafc.1c04989 article EN Journal of Agricultural and Food Chemistry 2021-10-29

The Co-61.8 wt% Al nanoparticles of 45 nm were prepared by hydrogen plasma-metal reaction (HPMR) method. display core shell structure with Al13Co4 and CoAl aluminum oxide (about 2 nm). Under ultrasonic irradiation, nanoporous fcc-Co produced successfully chemically dealloying the Co-Al at room temperature, whereas, without irradiation phase could hardly react sodium hydroxide solution. At 323 K be dealloyed to hcp-Co phases even irradiation. surface area under was larger than that sample...

10.1016/j.pnsc.2016.12.002 article EN cc-by-nc-nd Progress in Natural Science Materials International 2016-12-01

Microporous Co nanoparticles (NPs) with pore diameters of 0.38 nm have been prepared by dealloying Co–Al alloy NPs, which were subsequently annealed at different temperatures to synthesize microporous Co<sub>3</sub>O<sub>4</sub>–Co nanocomposites as electrode materials for pseudocapacitors.

10.1039/c6nj03828j article EN New Journal of Chemistry 2017-01-01

Intracellular GSH is the most abundant non-protein biothiol and acts as a central antioxidant to defend against aging toxins radicals. Meanwhile abnormal level of intracellular concentration directly related some diseases. In this case, detecting rapidly sensitively great significance. We synthesize simple fluorescent probe (named GP) which can discriminate from Cys (cysteine) or Hcy (homocysteine) presents 50-fold fluorescence increasing. The response time GP was only 5 min product GO (the...

10.3390/s19245348 article EN cc-by Sensors 2019-12-04

Novel coupling membrane systems with thermoresponsive switches composed of two different polymers PAAM and PAAC have been successfully developed. The membranes show significant positive switch characteristics higher speeds.

10.1039/c5ra14491d article EN RSC Advances 2015-01-01
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