A5083293783- Veterinary Equine Medical Research
- Veterinary Pharmacology and Anesthesia
- Anesthesia and Pain Management
- Reproductive Physiology in Livestock
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Anesthesia and Sedative Agents
- Cardiovascular Conditions and Treatments
- Veterinary Orthopedics and Neurology
- Meat and Animal Product Quality
- Hemodynamic Monitoring and Therapy
- Pharmacological Effects and Assays
- Exercise and Physiological Responses
- Muscle metabolism and nutrition
- Spine and Intervertebral Disc Pathology
- Animal health and immunology
- Diphtheria, Corynebacterium, and Tetanus
- Anesthesia and Neurotoxicity Research
- Mesenchymal stem cell research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Genetic and phenotypic traits in livestock
- Immune Response and Inflammation
- Tissue Engineering and Regenerative Medicine
- Mechanical Circulatory Support Devices
- Infective Endocarditis Diagnosis and Management
University of Liège
2016-2025
University of Zagreb
2023
Latvia University of Life Sciences and Technologies
2019-2021
Gdańsk Medical University
2021
Ghent University
2006
Physiol (Belgium)
2001
In equids, placentation is diffuse and nutrient supply to the fetus determined by uterine size. This correlates with maternal size affects intra-uterine development subsequent post-natal growth, as well insulin sensitivity in newborn. Long-term effects remain be described. this study, fetal growth was enhanced or restricted through ET using pony (P), saddlebred (S) draft (D) horses. Control P-P (n = 21) S-S 28) pregnancies were obtained AI. Enhanced transferring P S embryos into D mares...
In stud management, broodmares are commonly fed concentrates in late pregnancy. This practice, however, was shown to correlate with an increased incidence of osteochondrosis foals, which may be related insulin sensitivity. We hypothesized that supplementation the mare barley last trimester pregnancy alters pre-weaning foal growth, glucose metabolism and osteoarticular status. Here, pregnant multiparous saddlebred mares were forage only (group F, n=13) or both cracked B, n=12) from 7th month...
Osteochondrosis (OC) is the most common developmental orthopaedic disease in horses and represents a major problem to horse industry. The complete mechanism of this multifactorial not yet elucidated, but it accepted that OC lesions are result intrinsic genetic external factors. aim present work was evaluate relationship between breeding management OC. Breeding conditions were recorded, radiological examination performed 223 foals. Feeding practice housing analysed multivariate model...
Background Risk factors for cardiac diseases in horses have not been explored a large population of animals. Objectives To describe risk various hospital‐based horses. Animals Files 3,434 admitted at the Internal Medicine Department Liege Equine Teaching Hospital between 1994 and 2011 were reviewed those, 284 categorized as having moderate‐to‐severe disease. Methods Observational study. After calculating prevalence each disease, we tested whether breed (chi‐square test) or sex, age, body...
The aim of this study was to evaluate the effect transverse quadratus lumborum block (QLBLQL-T) on time first postoperative rescue analgesia in dogs submitted laparoscopic ovariectomy. A total twenty-three female were included. Dogs randomly assigned receive a bilateral QLBLQL-T, performed either with 0.3 mL kg−1 ropivacaine 0.5% [group QLB0.5% (n = 8)] or 0.33% QLB0.33% fentanyl-based protocol No-QLB 7)]. premedicated intravenously (IV) fentanyl 5 mcg kg−1, general anesthesia induced IV...
Equine anesthesia is related to high morbidity and mortality rates recent studies suggested that the period of recovery remains phase associated with greatest risk in horses. Intraoperative hypotension, hypoxemia, hypercapnia are recognized as potential determinants quality. This study, conducted at University Hospital Liege, aimed explore how these factors influence outcomes compare complications between non-emergency emergency procedures. We analyzed data from 1057 horses, a mean weight...
Epidural injections are commonly performed blindly in veterinary medicine. The aims of this study were to describe the lumbosacral ultrasonographic anatomy and assess feasibility an ultrasound-guided epidural injection technique dogs. A cross sectional anatomic atlas region ex vivo ultrasound images obtained two cadavers identify landmarks. Sixteen normal weight canine used establish variations for direct injection, using spinal needles or catheters. was finally cadavers, overweight five...
Abstract Osteochondrosis (OC) is a developmental disease that affects growing horses and severely their ability to perform. The genetic basis of its pathogenesis poorly understood. aim the study was analyze transcript profile leukocytes from affected with OC. Two transcriptome libraries were constructed OC‐affected non–OC‐affected using digital gene expression analysis (DGE) real‐time PCR. Statistical allowed selection 1,008 tags upregulated in group 1,545 group. Among these genes, 16...
Echocardiography has become a routine non-invasive cardiac diagnostic tool in most species. Accurate measurement of dimensions requires reference values, which are poorly documented goats. The aim the present study was to test inter-day repeatability and establish values two-dimensional (2D-) time-motion (M-) mode echocardiographic variables healthy adult Saanen Six goats were investigated three times by same observer at one-day interval using standardised 2D- M-mode protocol. intra-observer...
Bone marrow and adipose tissue represent the two most commonly exploited sources of adult mesenchymal stem cells for musculoskeletal applications. Unfortunately sampling bone fat is invasive does not always lead to a sufficient number cells. The present study describes novel method based on microbiopsy skeletal muscle in man, pigs, dogs horses. process includes explant sample, Percoll density gradient isolation subsequent culture We further characterized identified their clonogenic...
Intense physical exercise can induce the degranulation of neutrophils leading to an increase in plasma concentration neutrophil marker enzymes myeloperoxidase (MPO) and elastase (ELT). These have pro-oxidative pro-inflammatory properties may play a role exercised-induced muscular damage.To measure MPO ELT concentrations muscles endurance horses correlate them extent exercise-induced damage.Seven qualified on 120 km races were tested this study. Neutrophil count, serum creatine kinase (CK),...
Concerns over interactions between analgesics and experimental outcomes are a major reason for withholding opioids from rats undergoing surgical procedures. Only fraction of morphine injected intravenously reaches receptors responsible analgesia in the central nervous system. Intrathecal administration may represent way to provide with while minimizing amount injected. This study aimed assess whether intrathecally via direct lumbar puncture provides sufficient exposed acute pain (caudal...
To evaluate the effects of using ropivacaine combined with dexmedetomidine for sciatic and saphenous nerve blocks in dogs.7 healthy adult Beagles.In phase 1, dogs received each following 3 treatments random order: perineural injections 0.5% (0.4 mL/kg) mixed saline (0.9% NaCl) solution (0.04 mL/kg; DEX0PN), (1 μg/kg; DEX1PN), (2 DEX2PN). In 2, an IV injection diluted DEX1IV). For injections, dose was divided equally between 2 sites. Duration sensory blockade evaluated, plasma concentrations...
There is a growing interest in the use of natural compounds to tackle inflammatory diseases and cancers. However, most them face bioavailability solubility challenges reaching cellular compartments exert their potential biological effects. Polyphenols belong that class molecules, numerous efforts have been made improve overcome these problems. Curcumin widely studied for its antioxidant anti-inflammatory properties as well an anticancer agent. poor are often source concern with disappointing...
Laminitis is a pathology of the equine digit ultimately leading to failure dermo-epidermal interface. Neutrophil activation recognized as major factor in SIRS-associated laminitis and has recently been described induced endocrinopathic evidenced by presence myeloperoxidase (MPO). extracellular traps (NET) are released with neutrophil activation. This study aimed investigate activity MPO NET lamellar tissue equids presented naturally occurring laminitis. Samples five horses donkeys laminitis,...
Endocarditis is a rare heart condition with variable clinical expressions in equids. Risk factors for this disease are incompletely understood.Describe risk endocarditis equids.One hundred and fifty-three equids admitted to Liège University, 9 diagnosed 144 free from but the hospital differential diagnosis including disease.Retrospective case-control study.Equids were significantly younger (mean age = 4.84 +/- 5.74 years) than control 10.8 7.73 (P .01). No sex or breed predisposition was...
Background Downer cow syndrome (DCS) is often diagnosed in dairy cattle during the early post-partum period. The etiology of this condition not completely understood, as it can be related to energetic or electrolyte metabolism, well infectious diseases trauma. Hypothesis/Objectives aim study compare energy metabolism and insulin sensitivity indices various biochemical parameters between recumbent healthy cows. Animals A prospective has been undertaken on 361 80 Holstein Methods Plasmatic...
Abstract Background The use of non‐human primates (NHPs) in research remains a major societal concern with public expectations that appropriate anaesthetics and analgesics are used to minimize any pain or distress caused animals undergoing invasive procedures. A literature review was conducted examine the reporting anaesthesia analgesia methods surgical procedures, recovery from anaesthesia. Methods total 397 papers peer‐review journals published between 2010 2015 were examined. Results Only...