A5006716514- Neonatal Respiratory Health Research
- Neonatal and Maternal Infections
- Meat and Animal Product Quality
- Biochemical effects in animals
- Safe Handling of Antineoplastic Drugs
- Infant Nutrition and Health
- Ovarian cancer diagnosis and treatment
- Central Venous Catheters and Hemodialysis
- Food Quality and Safety Studies
- Drug Solubulity and Delivery Systems
- Urinary Tract Infections Management
- Respiratory Support and Mechanisms
- Pediatric Pain Management Techniques
- Aquatic Ecosystems and Phytoplankton Dynamics
- Non-Invasive Vital Sign Monitoring
- Water Treatment and Disinfection
- Marine and coastal ecosystems
- Inflammatory Biomarkers in Disease Prognosis
- Ultrasound and Hyperthermia Applications
- Educational Technology and Pedagogy
- Cancer Cells and Metastasis
- Chemical and Physical Properties in Aqueous Solutions
- Biocrusts and Microbial Ecology
- Adenosine and Purinergic Signaling
- Ferroptosis and cancer prognosis
Nanjing Normal University
2024
Ningxia University
2024
Affiliated Hospital of Southwest Medical University
2017-2023
Southwest Medical University
2015-2023
Shanghai Clinical Research Center
2023
Shanghai Pulmonary Hospital
2022
Tongji University
2022
Lund University
2022
Xi'an Jiaotong University
2021
Maternal and Child Health Care Hospital of Bao'an
2016
Abstract Small for gestational age (SGA) infants have an increased risk of necrotizing enterocolitis (NEC), but SGA has been found to not be a factor the deterioration NEC in previous literature. Few studies focused on correlative factors progression newborns. The present retrospective observational study was performed 64 with Bell’s stage II NEC. dependent variable that progressed III after diagnosis. A stepwise forward multivariate logistic regression model used select potential results...
By assessing silent mating-type information regulation 2 homolog 1 (SIRT1) nucleocytoplasmic shuttling and reactive oxygen species (ROS) levels in peripheral blood mononuclear cells (PBMCs), this study aimed to explore the role of SIRT1 premature infants after exposure hyperoxia assess protective effects resveratrol (Res).Firstly, ROS as well translocation expression PBMCs samples were evaluated from 40 with different amounts received at birth. Then, PBMCs, additional administered no birth,...
The objective of this study is to investigate perinatal risk factors for necrotizing enterocolitis (NEC) in very preterm infants.This retrospective included all infants with a gestational age <32 weeks attending our institution from 2013 2016. NEC group comprised patients enrolled according the inclusion criteria. Controls were selected database and matched gender, age, birth weight. Enumeration data are expressed as percentages (%) compared using χ2 test. Quantitative mean (standard...
To evaluate the effectiveness of cerebral regional oxygen saturation (crSO2) values, measured using near-infrared spectroscopy (NIRS), in assessing pain associated with peripherally inserted central catheter (PICC) premature infants.NIRS was used to measure crSO2 levels 48 infants gestational age (GA) < 32 weeks or a birth weight 1500 g. Premature infant profile (PIPP) scores, vital signs, transcutaneous tension (TcpO2), carbon dioxide (TcpCO2), and values were monitored. One-way repeated...
Objective: This study used near-infrared spectroscopy (NIRS) to detect the pulmonary regional oxygen saturation (rSO2) of premature infants. The oxygenation state lung tissue was also evaluated, which provided preliminary evidence regarding application NIRS in therapy for infants.Methods: measure rSO2 26 infants (gestational age <32 weeks). correlations between and arterial partial pressure (PaO2), (SaO2), pulse (SpO2) were analyzed. diagnostic value evaluated via both Pearson's correlation...
Abstract We aimed to analyze the risk factors of positive peripherally inserted central catheter (PICC)-related fungal colonization in preterm infants. This retrospective study collected data from 2018 2020. The enrolled infants who underwent PICC insertion were born at < 32 weeks’ gestation or birth weight 1500 g. demographics, PICC-related characteristics, and treatment information collected. Univariate multivariate analyses performed investigate for colonization. receiver operating...
Overexpression of the high mobility group protein A2 (HMGA2), an architectural transcription factor, has been linked to poor prognosis in many malignancies, although this remains controversial. Herein, we conducted a meta-analysis investigate whether HMGA2 prognostic value, and evaluated association between clinicopathologic factors malignancies. A total 29 studies involving 4114 patients were included meta-analysis. The pooled results demonstrated that elevated predicted overall survival...
Objective: This study aimed to explore the mechanism of p47phox-induced increase reactive oxygen species (ROS) in peripheral blood mononuclear cells (PBMCs) from premature infants after therapy, and determine a new target for oxidative stress injury alleviation clinical setting.Methods: First, ROS levels as well p47phox translocation expression PBMC samples were evaluated treatment with different concentrations oxygen. Then, changes all various parameters detected vitro PBMCs...
Our previous study used freeze-drying and biotin-avidin binding methods obtained nontargeted nanobubbles (N-NBs) ovarian cancer-targeting (LHRH-NBs, luteinizing hormone-releasing hormone nanobubbles). also identified the physical chemical properties of these two contrast agents, validated targeting ability underlying mechanisms LHRH-NBs in vitro. The present investigated imaging N-NBs nude mice their with tissues. models xenografts were divided into three groups, N-NB, LHRH-NB, SonoVue....
Oil-based drug delivery systems have been studied in different aspects. The present study proposes a new application for an oil-based system, focusing on controlled release until the reaches later part of small intestine. Bulk surfactants and interfacial were added into oil formulation to provide better mechanistic understating lipolysis. Validation modified vitro method shows overall conversion from medium-chain triglyceride (MCT oil) free fatty acids (FFA) 100 ± 4% five replicates. This...
ABSTRACT Overwintering is a crucial stage in the seasonal cycle of Microcystis , which often overlooked as state “suspended animation”. With global warming and increasing heatwaves, temperature rise during overwintering phase causes earlier recruitment or blooms. However, impact elevated overwinter temperatures on growth toxic aeruginosa remains poorly understood. This study aimed to elucidate physiological, metabolic molecular mechanisms at different (4°C, 6°C, 4°C → 6°C 8°C, 8°C) by...
Visceral pleural invasion (VPI) is a critical component in the staging of peripheral non-small cell lung carcinoma (NSCLC). We aim to investigate whether dual-block elastic stain increases visceral positivity compared with single-block stain. further analyze potential predictors invasion. 8419 NSCLC patients (including 6008 tumor size≤3 cm stage I) were divided into cohort using one paraffin block (single-block group, n = 5184) and dual blocks (dual-block 3235) for The VPI-positive rate...
Bronchopulmonary dysplasia (BPD) is a common disease caused by various factors and mechanisms in premature infants. Owing to lung hypoplasia the lack of alveolar surfactants infants, oxygen therapy often needed maintain adequate breathing. Nevertheless, prolonged can easily induce BPD, there currently no effective treatment. Therefore, prevention BPD infants during hospitalisation essential. Studies have revealed that prone position effectively improve oxygenation However, few studies...
Objective To explore the mechanism for increase in reactive oxygen species regulated by p47phox of nicotinamide adenine dinucleotide phosphate(NADPH) oxidase subunit peripheral blood mononuclear cells(PBMCs) after therapy premature infants. Methods According to different volume fractions oxygen, infants less than 32 weeks were divided into 3 groups: fractional concentration inspired oxygen(FiO2) 40% as high group.Premature without was control group.After 48 h, mL collected via radial...