A5067576791- Black Holes and Theoretical Physics
- Cancer therapeutics and mechanisms
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- Nonlinear Waves and Solitons
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National Kyushu Medical Center
2018-2025
Kyushu University
2018-2022
Czech Academy of Sciences, Institute of Physics
2018-2022
Czech Academy of Sciences
2018-2022
Tohoku University
1978-2018
Nara Women's University
2014-2016
The University of Tokyo
1999-2015
Ochanomizu University
2012-2014
Microbial Chemistry Research Foundation
1982-2012
Regional Development Agency
2010
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhosphorylation. IV. Selective phosphorylation of the primary hydroxyl group in nucleosidesKinichi Imai, Shoichiro Fujii, Kunio Takanohashi, Yoshiyasu Furukawa, Toru Masuda, and Mikio HonjoCite this: J. Org. Chem. 1969, 34, 6, 1547–1550Publication Date (Print):June 1, 1969Publication History Published online1 May 2002Published inissue 1 June 1969https://pubs.acs.org/doi/10.1021/jo01258a004https://doi.org/10.1021/jo01258a004research-articleACS...
The green fluorescent substance (G compound) isolated from the mycelium of Ere-mothecium ashbyii was presumed to be a ribityl derivative 6, 7-dimethyllumazine and already reported in previous paper. In present work 7, 8-trimethyllumazine synthesized, complete agreement ultraviolet spectrum between this product G compound, position group compound confirmed nitrogen at 8-position.
Es gibt keine ausreichende Evidenz für die Wirksamkeit von Januskinase-Inhibitoren (JAKi), einer Klasse gezielter synthetischer krankheitsmodifizierender Antirheumatika (tsDMARD), bei der Behandlung interstitiellen Lungenerkrankung (ILD), mit rheumatoider Arthritis (RA) assoziiert ist. Hier stellen wir einen Fall RA-ILD vor, gegenüber früheren Behandlungen refraktär war und ein günstiges Ansprechen auf Upadacitinib zeigte. Ein 69-jähriger Mann, ehemaliger Raucher, wurde diagnostiziert,...
Abstract The abuse of antibacterial drugs imposes a selection pressure on bacteria that has driven the evolution multidrug resistance in many pathogens. Our efforts to discover novel classes antibiotics combat these pathogens resulted discovery amycolamicin (AMM). absolute structure AMM was determined by NMR spectroscopy, X‐ray analysis, chemical degradation, and modification its functional groups. consists trans ‐decalin, tetramic acid, two unusual sugars (amycolose amykitanose),...
Rate constants for the reactions of OH radicals with commonly occuring amino acids and several enzyme proteins were determined by competition kinetics using p-nitrosodimethylaniline. From assumption that reaction an acid residue is restricted to surface region molecule, estimation rate constant was attempted. The calculated values cytochrome c lysozyme in good agreement those obtained experimentally.
Detailed explanation was made on the isolation of G compound from mycelium Er. ashbyii, and its purification. The composition this established as C13H18O6N4. A key for elucidating structure isolated yellow needles, m.p. 340∼345°(decomp.), photochemical decomposition products latter, it identified 6, 7-dimethyllumazine Rf value ultraviolet infrared spectra. From these facts analysis spectrum compound, shown assigned to compound.[chemical formula]
It was ascertained by paper partition chromatography, ultraviolet spectrum, and bioassay with L. casei that the green fluorescent substance, G compound, isolated from mycelium of Er. ashbyii readily reacts diacetyl or acetoin to form riboflavin. These results established structure 8-ribityl-6, 7-dimethyllumazine, formerly proposed author for compound. On other hand, a large quantity detected in culture filtrate, comparing amount those riboflavin compound these materials, assumption made...
Research Article| December 02, 2015 CIGN, A Strong‐Motion Seismic Network in Central Indo‐Gangetic Plains, Foothills of Himalayas: First Results R. K. Chadha; Chadha aCouncil Scientific and Industrial Research‐National Geophysical Institute, Uppal Road, Hyderabad 500007, India Search for other works by this author on: GSW Google Scholar D. Srinagesh; Srinagesh Srinivas; Srinivas G. Suresh; Suresh A. Sateesh; Sateesh S. Singh; Singh bInstituto de Geofísica, Universidad Nacional Autónoma...
A bstract We show how conformal field theory topological defects can relate solutions of open string for different boundary conditions. To this end we generalize the results Graham and Watts to include action on condition changing fields. Special care is devoted general case when nontrivial multiplicities arise upon defect action. Surprisingly fusion algebra realized fields only up a (star algebra) isomorphism.
4-Ribitylamino-5-aminouracil (II), which is regarded as an intermediate in the biosynthesis of riboflavin, was synthesized and formation 6, 7-dimethylribolumazine (III) riboflavin (IV) examined three cases, a mixture (II) crude enzyme solution prepared from Er. ashbyii, acetoin, were each incubated at 37°. In first two not observed, but lase case green fluorescent substance increase recognized. The confirmed to be its Rf values ultraviolet spectrum. From these results, it seems reasonable...
Various natural and synthetic compounds including alkaloids, terpenoids phenolics were tested for inhibition of the cell surface expression intercellular adhesion molecule-1 (ICAM-1) vascular (VCAM-1), both which are crucial in regulation immune response inflammation. Of 40 tested, two significantly downregulated VCAM-1 on murine endothelial cells (F-2) ten that ICAM-1 mouse myeloid leukemia (M1). Sanguinarine chloride (5) isoliquiritigenin (13) capable lowering levels VCAM-1. The...