A5063367718- Urticaria and Related Conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Autoimmune Bullous Skin Diseases
- Drug-Induced Adverse Reactions
- Mast cells and histamine
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Pharmaceutical Economics and Policy
- Autoimmune and Inflammatory Disorders
- Dermatology and Skin Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Pharmacovigilance and Adverse Drug Reactions
- Pharmaceutical studies and practices
- Chronic Kidney Disease and Diabetes
- Sarcoidosis and Beryllium Toxicity Research
- Psychiatric care and mental health services
- Chemotherapy-related skin toxicity
- Complement system in diseases
- Acute Kidney Injury Research
- Potassium and Related Disorders
- Circadian rhythm and melatonin
- Celiac Disease Research and Management
- Viral gastroenteritis research and epidemiology
Monash University
2019-2025
Eastern Health
2020-2025
Box Hill Hospital
2019-2025
Monash Medical Centre
2022-2025
Monash Health
2021-2024
Charité - Universitätsmedizin Berlin
2020-2024
Humboldt-Universität zu Berlin
2020-2024
Freie Universität Berlin
2020-2024
Royal Adelaide Hospital
2012-2021
St Vincent's Hospital Sydney
2021
Discharge against medical advice (DAMA) occurs when an in-patient chooses to leave the hospital before discharge is recommended by treating clinicians. The long-term outcomes of patients who DAMA are not well documented.The objective this and hospital-wide study examine characteristics DAMA, their rates readmission mortality after self-discharge.Administrative data admissions Flinders Medical Centre between July 2002 June 2011 were used compare readmissions among with those did not. adjusted...
Urticaria, a mast cell-mediated skin disease, manifests as acute or chronic, with the latter divided into spontaneous and inducible types requires individualized management, including identifying triggers comorbidities. Antihistamines, particularly second generation group, form mainstay of primary treatment plans consisting dosage adjustments and/or in combination other modalities depending on underlying disease control.
The correct classification of an adverse drug reaction (ADR) as allergy (immunological) or intolerance (non-immunological) has important clinical implications. aim this study was to examine the ability health professionals discriminate between and intolerance, classify severity ADR degree contraindication.Health were presented ten 'real-life' scenarios using online questionnaire asked to: categorise rate judge level contraindication causative drug. number proportion responses calculated for...
Chronic spontaneous urticaria (CSU) is characterized by mast cell-driven wheals, angioedema, or both. Two endotypes of CSU have been identified, ie, autoallergic and autoimmune CSU. The latter comes with high disease activity as well poor response to antihistamine omalizumab treatment.1 Dupilumab was recently demonstrated be effective in patients antihistamine-resistant CSU.2 Here, we report a patient who did not tolerate benefit from omalizumab, but showed complete dupilumab.
Angioedema occurs in up to 2% of those taking angiotensin-converting enzyme (ACE) inhibitors. Upper airway angioedema may potentially require endotracheal intubation or cricothyrotomy, and is usually unresponsive adrenaline. The bradykinin receptor antagonist icatibant proven be effective the treatment acute attacks hereditary angioedema, has also been reported associated with ACE inhibitors.To describe use for inhibitor-associated angioedema.We treated 13 consecutive emergency department...
Azathioprine hypersensitivity is a clinical syndrome which may manifest from isolated fever and rash to multi-organ failure. This rare condition usually self-limiting following the discontinuation of azathioprine. Therefore, it important maintain high index suspicion for reactions with azathioprine therapy. We report case in 69-year-old woman who developed cardiogenic shock Sweet's initiation her underlying autoantibodies neutrophil cytoplasmic antigens (ANCA) associated microscopic polyangiitis.
The issues and challenges in the diagnosis of drug allergy/hypersensitivity among children adults Asia are likely to be different from non-Asian countries.To study diagnostic modalities used evaluation management allergy/drug hypersensitivity reactions (DHRs) member societies Pacific Association Allergy, Asthma Clinical Immunology (APAAACI).A questionnaire comprising 41 questions was circulated electronically individual members APAAACI between January 23, 2020 March 6, 2020.Twenty-six...
BackgroundSince 2010, patients and physicians have collaborated to understand unmet needs of with mast cell diseases, incorporating mastocytosis activation disorders, which include syndromes.ObjectiveThis Open Innovation in Science project aims expand understanding the affected by encourage global communication among patient advocacy groups, physicians, researchers, industry, government. A major aim is support scientific community's efforts improve diagnosis, management, therapy, patients'...
Inpatient general medical units often look after older patients who have more complex co-morbidity including renal insufficiency. The consequences of insufficiency with respect to length hospital stay (LOS) and mortality not been well described in hospitalized patients.To use a inpatient population evaluate the impact reduced kidney function.Retrospective cross-sectional study.We studied 504 acute admissions through an Acute Assessment Unit between February November 2007. Patients were...