A5020584096- Urticaria and Related Conditions
- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Mast cells and histamine
- Food Allergy and Anaphylaxis Research
- Autoimmune and Inflammatory Disorders
- Plant Pathogens and Fungal Diseases
- Dermatology and Skin Diseases
- Fungal Infections and Studies
- Nail Diseases and Treatments
Humboldt-Universität zu Berlin
2021-2025
Charité - Universitätsmedizin Berlin
2021-2025
Freie Universität Berlin
2021-2025
Fraunhofer Institute for Translational Medicine and Pharmacology
2022-2025
Shanghai Skin Disease Hospital
2025
Tongji University
2025
Universitair Ziekenhuis Brussel
2023
Vrije Universiteit Brussel
2023
Misgav Ladach
2022
Universidad de Salamanca
2022
Urticaria, a mast cell-mediated skin disease, manifests as acute or chronic, with the latter divided into spontaneous and inducible types requires individualized management, including identifying triggers comorbidities. Antihistamines, particularly second generation group, form mainstay of primary treatment plans consisting dosage adjustments and/or in combination other modalities depending on underlying disease control.
Background The pathogenesis of chronic spontaneous urticaria (CSU) is still insufficiently understood. Recent findings suggest that immunoglobulins, in particular IgE but also IgA, play a role the development CSU. Objective Our aim was to assess differences clinical and laboratory markers between CSU patients with without lower levels serum IgA IgE. Methods We analyzed data 606 by dividing them into four groups based on their levels. were compared for spectrum symptoms, disease activity,...
In chronic spontaneous urticaria (CSU), autoimmune thyroid disease is the most common comorbidity, and many CSU patients have immunoglobulin (Ig)E or IgG autoantibodies to peroxidase (TPO). It remains unclear how anti-TPO IgE are linked each other associated with features, activity, therapeutic responses.
Autoimmunity is the break of tolerance to self-antigens that leads organ-specific or systemic diseases characterized by presence pathogenic autoreactive antibodies (AAb) produced plasmablast and/or plasma cells. AAb are prevalent in general population and not systematically associated with clinical symptoms. In contrast, some individuals, these drive development signs symptoms antibody-mediated autoimmune (AbAID). production, isotype profiles, glycosylations promoted pro-inflammatory...