A5003175174- Health, Environment, Cognitive Aging
- Congenital Anomalies and Fetal Surgery
- Air Quality and Health Impacts
- Environmental Justice and Health Disparities
- Risk Perception and Management
- Environmental and Social Impact Assessments
- Climate Change and Health Impacts
- Cleft Lip and Palate Research
- Folate and B Vitamins Research
- Urological Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Arsenic contamination and mitigation
- Healthcare Facilities Design and Sustainability
- Heavy Metal Exposure and Toxicity
- Prenatal Screening and Diagnostics
- Municipal Solid Waste Management
- COVID-19 Clinical Research Studies
- Genomics and Rare Diseases
- Global Public Health Policies and Epidemiology
- Vaccine Coverage and Hesitancy
- Congenital Diaphragmatic Hernia Studies
- Zoonotic diseases and public health
- Healthcare and Environmental Waste Management
- Craniofacial Disorders and Treatments
- Influenza Virus Research Studies
Istituto di Fisiologia Clinica
2016-2025
National Research Council
2016-2025
National Academies of Sciences, Engineering, and Medicine
2013-2024
ThrustMe (France)
2024
National Research Council
2016-2024
Casa Sollievo della Sofferenza
2017-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2017-2023
Czech Academy of Sciences, Institute of Physiology
2011-2022
Fondazione Toscana Gabriele Monasterio
2011-2021
Institute for Biomedical Research and Innovation
2020-2021
<h3>Introduction</h3> Published prevalence rates of congenital diaphragmatic hernia (CDH) vary. This study aims to describe the epidemiology CDH using data from high-quality, population-based registers belonging European Surveillance Congenital Anomalies (EUROCAT). <h3>Methods</h3> Cases delivered between 1980 and 2009 notified 31 EUROCAT formed case series. Prevalence over time was estimated multilevel Poisson regression, heterogeneity evaluated random component intercept. <h3>Results</h3>...
What are the long term trends in total (live births, fetal deaths, and terminations of pregnancy for anomaly) live birth prevalence neural tube defects (NTD) Europe, where many countries have issued recommendations folic acid supplementation but a policy mandatory fortification food does not exist?This was population based, observational study using data on 11,353 cases NTD associated with chromosomal anomalies, including 4162 anencephaly 5776 spina bifida from 28 EUROCAT (European...
Objective To validate the estimates of Global Burden Disease (GBD) due to congenital anomaly for Europe by comparing infant mortality data collected EUROCAT registries with WHO Mortality Database, and assessing significance stillbirths terminations pregnancy fetal (TOPFA) in interpretation statistics. Design, setting outcome measures is a network collecting on live births, deaths from 20 weeks’ gestation TOPFA. Data 29 19 countries were analysed 2005–2009, (deaths births at age <1 year)...
We studied 5,449 cases of cleft lip (CL) with or without palate (CL/P) identified between 1980 and 2000 from the EUROCAT network 23 registers (nearly 6 million births) in 14 European countries. investigated specific types defects associated clefts. Among CL/P (prevalence = 9.1 per 10,000), 1,996 (36.6%) affected only 3,453 (63.4%) involved CL (CLP). A total 3,860 (70.8%) occurred as isolated anomalies 1,589 (29.2%) were other such multiple congenital unknown origin (970), chromosomal (455)...
A total of 732 cases omphalocele and 274 gastroschisis was registered in 21 regional registers Europe (EUROCAT registers) during the period 1980-1990. The prevalence rates were 2.52 per 10,000 for 0.94 gastroschisis. There significant heterogeneity among regions omphalocele. Consistently higher than average found five centers British Isles. This large part linked to association between neural tube defects. female excess associated with defects, comparison an insignificant male other...
Rare diseases (RD) patient registries are powerful instruments that help develop clinical research, facilitate the planning of appropriate trials, improve care, and support healthcare management. They constitute a key information system supports activities European Reference Networks (ERNs) on rare diseases. A rapid proliferation RD has occurred during last years there is need to guidance for minimum requirements, recommendations standards necessary maintain high-quality registry. In...
<h3>Background</h3> The epidemiology of congenital small intestinal atresia (SIA) has not been well studied. This study describes the presence additional anomalies, pregnancy outcomes, total prevalence and association with maternal age in SIA cases Europe. <h3>Methods</h3> Cases delivered during January 1990 to December 2006 notified 20 EUROCAT registers formed population-based case series. Prevalence over time was estimated using multilevel Poisson regression, heterogeneity between...
The effects of noise on students’ health, well-being, and learning are growing concern among both the general public policy-makers in Europe. Several studies have highlighted consequences children’s performance at school. This study investigates relationship between judgment school goers aged 11–18 measurements aimed evaluating their exposure For this purpose, a questionnaire was administered to 521 individuals 28 classrooms eight schools four cities Italy, with different environmental...
The ongoing COVID-19 pandemic is shaking the foundations of public health governance all over world. Researchers are challenged by informing and supporting authorities on acquired knowledge practical implications. This commentary applies established theories risk perception research to reflects role perceptions in these unprecedented times. Moreover, it calls for utilizing improve communication, build trust contribute a collaborating governance.
Understanding the occurrence of symptoms resembling those severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a large nonhospitalized population at peak epidemic Italy is paramount importance; however, data are currently scarce.The aims this study were to evaluate association self-reported with SARS-CoV-2 nasopharyngeal swab (NPS) test results individuals and estimate associated disease (COVID-19) larger nontested population.EPICOVID19 self-administered cross-sectional voluntary...
The present study aims to evaluate whether influenza and pneumococcal vaccinations are associated with positive nasopharyngeal swab (NPS) testing detect SARS-CoV-2. Data from the Italian cross-sectional web-based survey (EPICOVID19), based on a self-selection sample of individuals aged ≥18, were considered. probability SARS-CoV-2 NPS test result as function or anti-pneumococcal vaccination was evaluated using multivariable logistic regression, stratifying analysis by age (<65 years, ≥65...
The study analyzed the association of fear contagion for oneself and family members (FMs) during first wave COVID-19 pandemic, with demographic socioeconomic status (SES) health factors. was performed within EPICOVID19 web-based Italian survey, involving adults from April–June 2020. Out 207,341 respondents, 95.9% completed questionnaire (60% women an average age 47.3 vs. 48.9 years among men). between SES characteristics, contacts cases, nasopharyngeal swab, self-perceived health, flu...
OBJECTIVES: This study examined the relationship between maternal tobacco and alcohol consumption during first trimester of pregnancy oral clefts. METHODS: Data were derived from a European multicenter case-control including 161 infants with clefts 1134 control infants. RESULTS: Multivariate analyses showed an increased risk cleft lip or without palate associated smoking (odds ratio [OR] = 1.79, 95% confidence interval [CI] 1.07, 3.04) (OR 2.28, CI 1.02, 5.09). The former number cigarettes...
Ultrasound scans in the mid-trimester of pregnancy are now a routine part antenatal care most European countries. Using data from registries congenital anomalies study was undertaken Europe. The objective to evaluate prenatal detection cleft lip with or without palate (CL(P)) and (CP). All CL(P) CPs suspected prenatally identified at birth period 1996-98 were registered 20 Congenital Malformation Registers following countries: Austria, Croatia, Denmark, France, Germany, Italy, Lithuania,...