A5011394593- Click Chemistry and Applications
- Environmental Chemistry and Analysis
- Catalytic Alkyne Reactions
- Pharmaceutical and Antibiotic Environmental Impacts
- Marine and coastal ecosystems
- Synthetic Organic Chemistry Methods
- Odor and Emission Control Technologies
- Synthesis and Reactions of Organic Compounds
- Atmospheric chemistry and aerosols
- Catalytic Cross-Coupling Reactions
- Synthesis of Organic Compounds
- Microbial Community Ecology and Physiology
- Inflammatory mediators and NSAID effects
King's College London
2023
University of East Anglia
2016
Norwich Research Park
2016
Eli Lilly (United States)
1988
Dimethylsulfoxonium propionate (DMSOP) is a recently identified and abundant marine organosulfur compound with roles in oxidative stress protection, global carbon sulfur cycling and, as shown here, potentially osmotolerance. Microbial DMSOP cleavage yields dimethyl sulfoxide, ubiquitous metabolite, acrylate, but the enzymes responsible, their environmental importance, were unknown. Here we report mechanisms diverse heterotrophic bacteria, fungi phototrophic algae not previously known to have...
Abstract Dimethylsulfoxonium propionate (DMSOP) is a recently identified and abundant marine organosulfur compound with purported roles in oxidative stress protection, global carbon sulfur cycling 1 . Diverse algae bacteria synthesise DMSOP from dimethylsulfoniopropionate (DMSP), which potentially limits the production of climate-active gases e.g., dimethylsulfide (DMS) generated microbial DMSP cleavage Here, was found at mM levels saltmarsh sediment, >10-fold higher than DMSP, orders...
A method that cleanly converts the 1,4-disubstituted 1,2,3-triazole products of copper-catalyzed 'click' dipolar cycloaddition reaction benzyl azide with terminal alkynes into 1,5-disubstituted triazoles is described. Selective N-alkylation 1,2,3-triazoles under microwave irradiation followed by debenzylation resulting 1,3,4-trisubstituted triazolium cations treatment potassium <i>tert</i>-butoxide.
<i>meso</i>-Bisalkynes and alkenes have potential as substrates for desymmetrization processes. The preparation of several <i>meso</i>-bis(1′-hydroxy-2′-propynyl)benzenes their derivatives from phthalaldehydes using inexpensive readily available reagents is described.
Abstract The acylhydroxyphenylacetic acids (III) are prepared, e.g. by Friedel‐ Crafts acylation of the esters (I) and subsequent saponification.