A5100360572- Microbial Community Ecology and Physiology
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Advanced Photocatalysis Techniques
- Enzyme Production and Characterization
- Marine and coastal ecosystems
- Adsorption and biosorption for pollutant removal
- Amino Acid Enzymes and Metabolism
- Genomics and Phylogenetic Studies
- Advanced oxidation water treatment
- COVID-19 Clinical Research Studies
- Water Treatment and Disinfection
- Antifungal resistance and susceptibility
- Polyamine Metabolism and Applications
- Wastewater Treatment and Nitrogen Removal
- Nanomaterials for catalytic reactions
- Methane Hydrates and Related Phenomena
- SARS-CoV-2 and COVID-19 Research
- Enzyme Catalysis and Immobilization
- Environmental remediation with nanomaterials
- Microbial Metabolic Engineering and Bioproduction
- Photosynthetic Processes and Mechanisms
- Pharmaceutical and Antibiotic Environmental Impacts
- Long-Term Effects of COVID-19
- Marine Biology and Ecology Research
Shanghai University
2022-2025
Dalian Maritime University
2024-2025
Beijing University of Civil Engineering and Architecture
2025
China West Normal University
2025
Guangdong University of Technology
2024
Shandong University
2015-2024
Ocean University of China
2018-2024
Xuzhou Medical College
2017-2024
Qingdao National Laboratory for Marine Science and Technology
2019-2024
Inner Mongolia Medical University
2017-2024
With the rapid development of “Internet plus”, medical care has entered era big data. However, there is little research on data (MBD) from perspectives bibliometrics and visualization. The substantive basic aspects MBD itself also rare. This study aims to explore current status through visualization analysis journal papers related MBD. We analyze a total 988 references which were downloaded Science Citation Index Expanded Social databases Web time span was defined as “all years”. GraphPad...
Limited data are available for clinical characteristics of patients with coronavirus disease 2019 (COVID-19) outside Wuhan. This study aimed to describe the COVID-19 and identify risk factors severe illness in Jiangsu province, China. Clinical hospitalized were retrospectively collected 8 hospitals from cities findings described analyzed. By Feb 10, 2020, 202 enrolled. The median age was 44.0 years (interquartile range, 33.0-54.0). 55 (27.2%) had comorbidities. At onset illness, common...
Abstract We report epidemiologic, laboratory, and clinical findings for 7 patients with 2019 novel coronavirus disease in a 2-family cluster. Our study confirms asymptomatic human-to-human transmission through close contacts familial hospital settings. These might also serve as practical reference diagnosis medical treatment.
Methane is supersaturated in surface seawater and shallow coastal waters dominate global ocean methane emissions to the atmosphere. Aerobic oxidation (MOx) can reduce atmospheric evasion, but magnitude control of MOx remain poorly understood. Here we investigate sources fates East China Sea map rates by training machine-learning models. We show produced during methylphosphonate decomposition under phosphate-limiting conditions sedimentary release also source methane. High observed these...
Abstract Symbiodinium are the photosynthetic endosymbionts for corals and play a vital role in supplying their coral hosts with products, forming nutritional foundation high-yield reef ecosystems. Here, we determine cryo-electron microscopy structure of photosystem I (PSI) supercomplex PSI core composed 13 subunits including 2 previously unidentified subunits, PsaT PsaU, as well peridinin-Chl / c -binding light-harvesting antenna proteins (AcpPCIs). The PSI–AcpPCI exhibits distinctive...
Copper loaded activated carbon (Cu-AC) was prepared by impregnating it with cupric nitrate followed microwave heating and then used for removing dyes in wastewater.
Abstract Predator-prey interactions play important roles in the cycling of marine organic matter. Here we show that a Gram-negative bacterium isolated from sediments ( Pseudoalteromonas sp. strain CF6-2) can kill Gram-positive bacteria diverse peptidoglycan (PG) chemotypes by secreting metalloprotease pseudoalterin. Secretion enzyme requires Type II secretion system. Pseudoalterin binds to glycan strands Gram positive bacterial PG and degrades peptide chains, leading cell death. The released...
Alginate lyases that degrade alginate via a β-elimination reaction fall into seven polysaccharide lyase (PL) families. Although the structures and catalytic mechanisms of in other PL families have been clarified, those family PL6 yet to be revealed. Here, crystal structure AlyGC, from marine bacterium Glaciecola chathamensis S18K6T, was solved, its mechanism illustrated. AlyGC is homodimeric enzyme adopts distinct lyases. Each monomer contains N-terminal domain functionally unknown...
The use of nanotechnology to suppress crop diseases has attracted increasing attention in agriculture. present work investigated the antifungal efficacy copper oxide nanoparticle (CuO NP)-embedded hydrogels, which were synthesized by loading CuO nanoparticles (NPs) hydrogels formed from cross-linked interaction between chitosan and acrylic acid, against Fusarium wilt lettuce (Lactuca sativa) caused oxysporum f. sp. lactucae. In comparison with NPs, 7-day Cu dissolution NP-embedded was...
Cryptophyte plastids originated from a red algal ancestor through secondary endosymbiosis. photosystem I (PSI) associates with transmembrane alloxanthin-chlorophyll a/c proteins (ACPIs) as light-harvesting complexes (LHCs). Here, we report the structure of photosynthetic PSI-ACPI supercomplex cryptophyte Chroomonas placoidea at 2.7-Å resolution obtained by crygenic electron microscopy. represents unique PSI-LHCI intermediate in evolution to diatom PSI-LHCI. The is composed monomeric PSI core...
The proteasome, a key component of the ubiquitin-proteasome pathway, has emerged as an important cancer therapeutic target. PS-341 (also called Bortezomib or Velcade) is first proteasome inhibitor approved for newly diagnosed and relapsed multiple myeloma currently being tested in many clinical trials against other types cancers. One proposed mechanism by which exerts its anticancer effect inactivation nuclear factor-kappaB (NF-kappaB) through prevention IkappaB(alpha) degradation. In this...
Abstract Poly ( ADP ) ribose polymerase PARP plays a key role in DNA repair and is highly expressed small cell lung cancer SCLC ). We investigated the therapeutic impact of inhibition . In vitro cytotoxicity veliparib, cisplatin, carboplatin, etoposide singly combined was determined by MTS 9 lines (H69, H128, H146, H526, H187, H209, DMS 53, 153, 114). Subcutaneous xenografts athymic nu/nu mice H146 H128 cells with relatively high low platinum sensitivity, respectively, were employed for vivo...
A waste-derived adsorbent was prepared from waste carbon that obtained the monosodium glutamate production, by microwave heating under ultrasonic spray conditions for removing methylene blue (MB) wastewater.
The ataxia telangiectasia-mutated and Rad3-related (ATR) kinase checkpoint pathway maintains genome integrity; however, the role of sirtuin 2 (SIRT2) acetylome in regulating this is not clear. We found that deacetylation ATR-interacting protein (ATRIP), a regulatory partner ATR, by SIRT2 potentiates ATR checkpoint. interacts with deacetylates ATRIP at lysine 32 (K32) response to replication stress. K32 drives autophosphorylation signaling facilitates DNA fork progression recovery stalled...
Accurate and updated road network data is vital in many urban applications, such as car-sharing, logistics. The traditional approach to identifying the network, i.e., field survey, requires a significant amount of time effort. With wide usage GPS embedded devices, huge trajectory has been generated by different types mobile objects, which provides new opportunity extract underlying network. However, existing trajectory-based map recovery approaches require empirical parameters do not utilize...
Colorectal cancer (CRC) is now one of the leading causes incidence and mortality. Although nanomaterial-based drug delivery has been used for treatment colorectal cancer, inferior targeting ability existing nanocarriers leads to inefficient side effects. Moreover, majority intravenously administered nanomaterials aggregate into reticuloendothelial system, leaving a certain hidden risk human health. All those problems gave great demands further construction well-performed biocompatible in...