- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Acute Myocardial Infarction Research
- Hydrological Forecasting Using AI
- Water resources management and optimization
- Hydrology and Watershed Management Studies
- Adhesion, Friction, and Surface Interactions
- Concrete Properties and Behavior
- Epoxy Resin Curing Processes
- Innovative concrete reinforcement materials
- Tribology and Lubrication Engineering
- Cardiac electrophysiology and arrhythmias
- Mechanical stress and fatigue analysis
- Cardiac Ischemia and Reperfusion
- Fluid Dynamics Simulations and Interactions
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac Imaging and Diagnostics
- Cancer Treatment and Pharmacology
- Coronary Interventions and Diagnostics
- Cardiac Arrhythmias and Treatments
- Anesthesia and Sedative Agents
- Congenital Heart Disease Studies
- Vascular Procedures and Complications
- Chemotherapy-induced cardiotoxicity and mitigation
Klinikum Chemnitz
2020-2025
Technical University of Darmstadt
2023
Universiti Tunku Abdul Rahman
2021-2022
TU Dresden
2014-2022
Shibuya University Network
2018
University Hospital Carl Gustav Carus
2017
Military Technical College
1999
Percutaneous mechanical circulatory support devices are increasingly used in acute myocardial infarction complicated by cardiogenic shock (AMI-CS), despite limited evidence for their effectiveness. The aim of this study was to evaluate outcomes associated with use the Impella device compared intra-aortic balloon pump (IABP) and medical treatment patients AMI-CS. Data AMI-CS treated at European tertiary care hospitals were collected retrospectively. All underwent early revascularization...
The use of percutaneous left ventricular assist devices in patients with acute myocardial infarction complicated by cardiogenic shock (AMICS) is evolving. aim the study was to assess long-term outcome AMICS depending on early initiation Impella CP® support prior a coronary intervention (PCI).We retrospectively reviewed all who underwent PCI and between 2014 2016 for at our institution. We compared survival discharge those before (pre-PCI) after (post-PCI) PCI.A total 73 consecutive (69±12...
This paper evaluates the effect of blood loss on in-stent stenosis after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Nine hundred and ninety-seven who underwent PCI for AMI as well follow-up angiography at 6-12 months from two centers were categorized into three groups based peri-interventional primary (mild, <1 mmol/L moderate, 1-2 mmol/L; severe > 2 mmol/L). The endpoint was to evaluate incidence severity revascularization rate. mild, 19.3%,...
Background: Cardiotoxicity is a major concern in patients undergoing chemotherapy, requiring interdisciplinary management. However, the extent to which cardiotoxicity managed outpatient setting among these specialists may vary, potentially leading gaps patient care. Methods: This questionnaire study assessed current practices and perceptions of cardiologists, oncologists gynaecologists regarding management chemotherapy Germany. Results: A total 1,329 medical professionals were contacted via...
The current goal of treatment after acute ischemic stroke is the increase cerebral blood flow (CBF) in brain tissue. Intra-aortic balloon pump (IABP) counterpulsation setting cardiogenic shock able to reduce left ventricular afterload and coronary flow. effects an IABP on CBF have not been sufficiently examined. We hypothesize that use especially enhances patients with pre-existing heart failure.In this pilot study, 36 subjects were examined investigate effect middle artery (MCA)...
The APACHE II score assesses patient prognosis in intensive care units. Different disease entities are predictable by using a specific factor called Diagnostic Category Weight (DCW). We aimed to validate the prognostic value of patients treated with percutaneous left ventricular assist device because refractory cardiogenic shock (CS). From Dresden Impella Registry, we analyzed 180 receiving an CP®. main outcome was observed intrahospital mortality (S^(thosp)), which compared predicted...
In der interventionellen Kardiologie ist eine stetig zunehmende Zahl an Patienten zu verzeichnen, die aufgrund ihres Alters und ihrer Komorbiditäten trotz eindeutiger prognoserelevanter Koronarstenosen nicht einer leitliniengerechten operativen Myokardrevaskularisation zugeführt werden können. Insbesondere mit relevanter, ischämisch bedingter Einschränkung linksventrikulären Pumpfunktion profitieren von Revaskularisation. Gefürchtete Komplikationen bei diesen sind Kreislaufdepression...
A precise prognosis is of imminent importance in intensive care medicine. This article provides data showing the overestimation intrahospital mortality by APACHE II score various subgroups cardiogenic shock patients treated with a percutaneous left ventricular assist device. The set includes additional baseline characteristics regarding age, pre-existing diseases, coronary artery disease, cardiopulmonary resuscitation, and hemodynamic parameter not included score. Further were provided which...
Despite the routine use of percutaneous mechanical circulatory support (pMCS) with Impella heart pump, vascular and bleeding complications may occur during removal or without pre-closure. To safely close large-bore access (LBA), post-hoc selection appropriate treatment is critical to patient recovery survival. Femoral artery typically utilized for LBA, axillary a common alternative, especially in instance severe peripheral disease. Optimization outcomes efficiency pMCS can be achieved...
Abstract Background The management of cardiotoxicity, a significant concern in chemotherapy patients, necessitates multidisciplinary approach. This study investigates the variability cardiotoxicity outpatient settings across different medical specialties, which may lead to inconsistencies patient care. Methods An extensive questionnaire-based was conducted assess current practices and viewpoints cardiologists, oncologists, gynecologists among patients receiving Germany. survey engaged 1,329...
Abstract This work presents an investigation on the influence of pitting in EHL rolling contact. The pit-ting geometry comes as extension architecture for multi-physical numerical calculations ofrolling element bearing contacts based OpenFOAM. model utilized is built according to thestate-of-the-art fluid-solid interaction and electro-quasi-static fields. In this framework, con-tact reduced be two dimensional order reduce computing costs needed. changesin electric properties, that are caused...
This work presents an investigation on the influence of pitting in EHL rolling contact. The geometry comes as extension architecture for multi-physical numerical calculations element bearing contacts based OpenFOAM. model utilized is built according to state-of-the-art fluid–solid interaction and electro-quasi-static fields. In this framework, contact reduced be two dimensional order reduce computing costs needed. changes electric properties, which are caused by pittings, measured using...
Background:The mortality of acute myocardial infarction complicated by cardiogenic shock (AMICS) has remained constantly high in the last years despite advanced treatment strategies.Consequently, application percutaneous implantable left ventricular assist devices (pLVAD) like microaxial blood pump systems for temporary mechanical support is evolving.Purpose: The aim current analysis was to investigate clinical course and long-term outcome patients with AMICS receiving pLVAD...
Abstract Background Cardiogenic shock (CS) is often associated with severe heart rhythm disturbances (SHRD). Percutaneous left ventricular assist devices (pLVAD) can actively unload the ventricle (LV) using a micro-axial pump and resulting in decreased end-diastolic pressure wall tension. These parameters are suspected to induce maintain rhythmological instability. Purpose In current study, we firstly describe termination of SHRD immediately (less than 5 minutes) after LV-unloading CS...
Abstract Background Cardiogenic shock (CS) is a state of end-organ hypoperfusion due to cardiac output failure and characterized by high mortality. Percutaneous left ventricular assist devices (pLVAD), like the Impella® system, support function provide sufficient oxygen supply all tissues, which might improve outcome. In current study, we investigated gender-specific differences in large, propensity score matched cohort patients receiving an Impella CP® CS. Beside all-cause mortality,...
The modal properties of fluid-structure system were investigated.A standard finite element software (COSMOS) was adapted to detect the a tank partially filled with liquid.A concentrated mass added nodes wet part resemble fluid influence.Experimental work conducted help devise an empirical relation for relative that fluid.The validity method confirmed through laboratory measurements and comparison results published work, which demonstrated good agreement.
Curing concrete is actually maintaining the moisture content as long possible in order for to develop its hardening properties during early stages. However, good curing rarely occur and that's due lack of knowledge by workers at site shortage water area. Therefore, investigate produce a self-curing that relays on itself without need an outer source agent with similar performance normal using external agent. This paper investigating effect baby diapers The mix design consists high strength...