A5081842240- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Caveolin-1 and cellular processes
- Cardiac Arrest and Resuscitation
- Cardiomyopathy and Myosin Studies
- Cardiac Imaging and Diagnostics
- Cancer, Hypoxia, and Metabolism
- Takotsubo Cardiomyopathy and Associated Phenomena
- Gout, Hyperuricemia, Uric Acid
- Acute Myocardial Infarction Research
- Mechanical Circulatory Support Devices
- Angiogenesis and VEGF in Cancer
- Cardiac Health and Mental Health
- Cardiac Structural Anomalies and Repair
- Immune cells in cancer
- Heart Failure Treatment and Management
- Diabetes Treatment and Management
- Platelet Disorders and Treatments
- Trace Elements in Health
- Cardiovascular Effects of Exercise
- Coronary Interventions and Diagnostics
Klinikum Chemnitz
2019-2025
Chemnitz University of Technology
2022-2023
TU Dresden
2011-2022
Intensive Care Foundation
2021
University Hospital Augsburg
2019
University Hospital Carl Gustav Carus
2011-2017
Steinbeis Foundation
2015
Christophorus Kliniken
2010
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2009
University of Freiburg
1995
Despite the use of established 3D-mapping systems, invasive electrophysiological studies and catheter ablation require high radiation exposure patients medical staff. This study investigated whether electroanatomic tracking in prerecorded X-ray images on top an existing system has any impact exposure. Two hundred ninety-five consecutive were either ablated with guidance traditional CARTO-3 (c3) or help CARTO-UNIVU (cU): [typical atrial flutter (AFL) n = 58, drug refractory fibrillation (AF)...
This paper evaluates the effect of blood loss on in-stent stenosis after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Nine hundred and ninety-seven who underwent PCI for AMI as well follow-up angiography at 6-12 months from two centers were categorized into three groups based peri-interventional primary (mild, <1 mmol/L moderate, 1-2 mmol/L; severe > 2 mmol/L). The endpoint was to evaluate incidence severity revascularization rate. mild, 19.3%,...
Background: Cardiotoxicity is a major concern in patients undergoing chemotherapy, requiring interdisciplinary management. However, the extent to which cardiotoxicity managed outpatient setting among these specialists may vary, potentially leading gaps patient care. Methods: This questionnaire study assessed current practices and perceptions of cardiologists, oncologists gynaecologists regarding management chemotherapy Germany. Results: A total 1,329 medical professionals were contacted via...
The current goal of treatment after acute ischemic stroke is the increase cerebral blood flow (CBF) in brain tissue. Intra-aortic balloon pump (IABP) counterpulsation setting cardiogenic shock able to reduce left ventricular afterload and coronary flow. effects an IABP on CBF have not been sufficiently examined. We hypothesize that use especially enhances patients with pre-existing heart failure.In this pilot study, 36 subjects were examined investigate effect middle artery (MCA)...
Objectives Patients with chest pain and normal coronary arteries often suffer from physical psychological symptoms. Therefore, this study aimed to examine the incidence of mental symptoms in patients angiographic exclusion a heart disease. Design In 253 disease type intensity their were evaluated before after angiography. addition, psychopathological was quantified by standardised questionnaires such as general anxiety depression (HADS), heart-focused (CAQ), hypochondria (Whiteley Index)...
Ablation index (AI)-guided ablation according to the CLOSE protocol is very effective in terms of chronic pulmonary vein isolation (PVI). However, optimal radiofrequency (RF) power remains controversial. Here, we thought investigate efficiency and safety an AI-guided fixed circumferential 50 W high-power short-duration (HPSD) PVI using protocol.In a single-center trial, 40 patients underwent randomized without esophageal temperature monitoring. In 20 guided HPSD was followed irrespective...
Summary A growing body of evidence suggests a pivotal role inflammatory processes in AF bidirectional manner. Infiltrating leukocytes seem to promote both structural and electrical remodelling patients with AF. Monocyte-platelets-aggregates (MPAs) are sensitive markers platelets monocyte activation. So far it is not clear whether the content MPAs affected by The present study examined activation monocytes elderly an aortic stenosis dependence These known have high prevalence Flow-cytometric...
Neointimal inflammation and angiogenesis are important contributors of progression destabilization the atherosclerotic plaque. While role vascular endothelial growth factor (VEGF) its receptors VEGF-R1 (Flt-1) VEGF-R2 (Flk-1) in this process has clearly been defined, expression VEGF-R3 (Flt-4) only documented on lymphatic tumor endothelium. This study examined Flt-4 human plaque explored implications for disease.Carotid artery thrombendartherectomy specimens from 10 patients with unstable...
Ablation of atrial fibrillation (AF) with high-power-short-duration (HPSD) radiofrequency (RF) technology is emerging as a new standard care in many electrophysiology laboratories. While procedural short-term efficacy and efficiency very promising, little known about mid- to long-term effects HPSD ablation for pulmonary vein isolation (PVI) left substrate modification.In single-center registry, 412 AF procedures were performed 400 individual patients using standardized CLOSE protocol-guided...
AbstractBackground Accumulating evidence indicates that target temperature management (TTM) is benefi cial in patients resuscitated after cardiac arrest since it appears to improve neurological outcome. However, the optimal cooling method (surface vs intravascular) has not yet been specifi ed. Substantial heart disease present most of these and therefore haemodynamic eff ects need be considered very carefully. We analysed response TTM treated with surface versus intravascular following...
Abstract Background Various randomized multicenter studies have shown that percutaneous left atrial appendage closure (LAAC) is not inferior in stroke prevention compared to vitamin K antagonists (VKA) and can be performed safely effectively. Aims The prospective ORIGINAL registry the Free State of Saxony (saxOnian RegIstry analyzinG followINg Appendage cLosure) investigated efficiency safety LAAC with Watchman or Amulet device a real word setting. A special focus was put on influence...
The establishment of venous access is one the driving factors for complications during implantation pacemakers and defibrillators (cardiac implantable electronic devices [CIED]). Recently, a novel approach accessing cephalic vein CIED by puncture (CVP) using modified Seldinger technique has been described, promising high success rates simplified handling with steeper learning curves. In this single-center registry, we analyzed safety efficiency CVP to SVP after defining as primary route in...
Abstract Glomerular nephropathy resulting from the genetic defects in COL4A3/4/5 genes including classical Alport syndrome (AS) is second commonest hereditary kidney disease characterized by persistent haematuria progressing to need of replacement therapy, frequently associated with sensorineural deafness, and occasionally ocular anomalies. Diagnosis management glomerulopathy a great challenge due its phenotypic heterogeneity, multiple modes inheritance, variable expressivity, penetrance...