- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Airway Management and Intubation Techniques
- Infection Control and Ventilation
- Hemodynamic Monitoring and Therapy
- Respiratory Support and Mechanisms
- Tracheal and airway disorders
- COVID-19 and Mental Health
- Hip and Femur Fractures
- Hospital Admissions and Outcomes
- Emergency and Acute Care Studies
- Health Systems, Economic Evaluations, Quality of Life
- Anesthesia and Sedative Agents
- Surgical Simulation and Training
- Healthcare Policy and Management
- Anesthesia and Pain Management
- Diversity and Career in Medicine
- Delphi Technique in Research
- Healthcare Operations and Scheduling Optimization
- Cardiac Arrest and Resuscitation
- Aortic aneurysm repair treatments
- Medical Education and Admissions
- Medical Malpractice and Liability Issues
- Trauma and Emergency Care Studies
- Health Services Management and Policy
Guy's and St Thomas' NHS Foundation Trust
2019-2024
Singapore General Hospital
2024
King's College London
2008-2024
Royal College of Anaesthetists
2017-2021
National Health Service
2021
Memorial Hospital
2021
Aga Khan University Hospital
2021
London School of Hygiene & Tropical Medicine
2021
Weill Cornell Medical College in Qatar
2021
St Thomas' Hospital
2019-2021
Summary Healthcare workers involved in aerosol‐generating procedures, such as tracheal intubation, may be at elevated risk of acquiring COVID‐19. However, the magnitude this is unknown. We conducted a prospective international multicentre cohort study recruiting healthcare participating intubation patients with suspected or confirmed Information on episodes, personal protective equipment use and subsequent provider health status was collected via self‐reporting. The primary endpoint...
Background Preoperative risk prediction is important for guiding clinical decision-making and resource allocation. Clinicians frequently rely solely on their own judgement rather than objective measures. We aimed to compare the accuracy of freely available surgical tools with subjective assessment in predicting 30-day mortality. Methods findings conducted a prospective observational study 274 hospitals United Kingdom (UK), Australia, New Zealand. For 1 week 2017, risk, surgical, outcome data...
We conducted a 5-year retrospective cohort study on women undergoing caesarean section to investigate factors influencing the operating room-to-incision interval. Time-to-event analysis was performed for category-1 using Cox proportional hazards regression model. Covariates included: anaesthetic technique; body mass index; age; parity; time of delivery; and gestational age. Binary logistic 5-min Apgar score ≥ 7. There were 677 who underwent met entry criteria. Unadjusted median (IQR [range])...
Because of the anticipated surge in cases requiring intensive care unit admission, high aerosol-generating risk tracheal intubation, and specific requirements coronavirus disease (COVID-19) patients, a dedicated Mobile Endotracheal Rapid Intubation Team (MERIT) was formed to ensure that highly skilled team would be deployed manage airways this cohort patients. Here, we report our intubation experience activity as well patient outcomes during COVID-19 pandemic. The MERIT members followed...
Intra-operative hypotension frequently complicates anaesthesia in older patients and is implicated peri-operative organ hypoperfusion injury. The prevalence corresponding treatment thresholds of are incompletely described the UK. This study aimed to identify intra-operative its UK practice. Patients aged ≥ 65 years were studied prospectively from 196 hospitals within a 48-hour timeframe. primary outcome was incidence (mean arterial pressure <65 mmHg; systolic blood reduction >20%; <100...
To establish the prevalence, risk factors and implications of suspected or confirmed coronavirus disease 2019 (COVID-19) infection among healthcare workers in United Kingdom (UK).Cross-sectional observational study.UK-based primary secondary care.Healthcare aged ≥18 years working between 1 February 25 May 2020.A composite endpoint laboratory-confirmed diagnosis SARS-CoV-2, self-isolation hospitalisation due to COVID-19.Of 6,152 eligible responses, was present 1,806 (29.4%) workers, whom 49...
Abstract Small proline‐rich repeat protein 1A (SPRR1A) is expressed in dorsal root ganglion (DRG) neurons following peripheral nerve injury but it not known whether SPRR1A differentially to versus central DRG projections and a detailed characterization of expression sensory neuron subpopulations spinal cord has been performed. Here we use immunocytochemical techniques characterize sciatic nerve, root, column adult mice. was detected naïve cord, DRG, or nerves there minimal the centrally...
Summary Background Critical care beds are a limited resource, yet research indicates that recommendations for postoperative critical admission based on patient‐level risk stratification not followed. It is unclear how prioritisation decisions made in real‐world settings and the effect of this outcomes. Methods This was prespecified analysis an observational cohort study adult patients undergoing inpatient surgery, conducted 274 hospitals across UK Australasia during 2017. The primary outcome...
Summary The perceived risk of transmission aerosolised viral particles from patients to airway practitioners during the COVID‐19 pandemic led widespread use aerosol precautions, including personal protective equipment and modifications anaesthetic technique. these precautions on peri‐operative complications has not been assessed outside simulation studies. This prospective, national, multicentre cohort study aimed quantify this risk. Adult undergoing general anaesthesia for elective or...
Background: The double-opposing Z-plasty palatal repair, as reported by Dr. Furlow, is one of the most popular methods primary cleft palate repair. However, repair originally described difficult to perform on wide clefts. authors have modified original altering hard flap design allow for better mobilization and improved closure cleft. Methods: performed a retrospective review 500 consecutive children undergoing repairs with or without islandization hemipalate its vascular pedicle over...
Nitrous oxide in oxygen (N 2 O/O ) inhalation sedation is used less commonly by Singapore dentists than their counterparts the United Kingdom and States. Using this technique, trained often perform dual roles of a sedationist an operating dentist. This paper describes mechanism action N O highlights modern gas delivery system dentistry. The built-in safety features unique helps to ensure that patient-specific therapeutic dosages are effectively safely administered dentists. Existing evidence...
Introduction The admission of high-risk patients to critical care after surgery is a recommended standard care. Nevertheless, poor compliance against this recommendation has been repeatedly demonstrated in large epidemiological studies. It unclear whether due reasons capacity, equipoise, quality clinical or because hospitals are working creatively create capacity for augmented on normal surgical wards. EPIdemiology Critical Care Surgery study aims address these uncertainties. Methods and...
The recent development of electronic logbooks with secure off-device data storage provides a rich resource for research. We present the largest analysis anaesthetic to date, from 494,235 cases logged by 964 anaesthetists over 4-year period. Our describes and compares annual case-load supervision levels different grades across UK Republic Ireland. calculated number undertaken per year grade (median (IQR [range]) core trainees = 388 (252-512 [52-1204]); specialist 344 (228-480 [52-1144]);...
There were more applications for higher specialty training posts in anaesthesia the UK starting August 2021 than previous years, with approximately two-thirds being unsuccessful. We surveyed applicants to investigate their experience of recruitment process (response rate 536/1056; 51%). Approximately 61% respondents not offered ST3 (n = 326). enquired about career plans next 12-24 months. Most (79%) intended take up a post equivalent third year core or clinical fellow from 2021. Other...
The cause of adverse weekend clinical outcomes remains unknown. In 2013, the “NHS Services, Seven Days a Week” project was initiated to improve access services across seven-day week. Three years on, we sought analyse impact such changes English NHS. Aggregated trust-level data on crude mortality rates, Summary Hospital-Level Mortality Indicator (SHMI), mean length stay (LOS), A&E admission and four-hour breach rates were obtained from national Hospital Episode Statistics datasets NHS,...