Mohammed Jafar

ORCID: 0000-0002-3581-0877
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About
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Research Areas
  • Drug Solubulity and Delivery Systems
  • Advanced Drug Delivery Systems
  • Nanoparticle-Based Drug Delivery
  • Advancements in Transdermal Drug Delivery
  • Helicobacter pylori-related gastroenterology studies
  • Heusler alloys: electronic and magnetic properties
  • Curcumin's Biomedical Applications
  • Nanoparticles: synthesis and applications
  • Essential Oils and Antimicrobial Activity
  • Rare-earth and actinide compounds
  • Inflammatory mediators and NSAID effects
  • Banana Cultivation and Research
  • Thin-Film Transistor Technologies
  • MXene and MAX Phase Materials
  • Semiconductor materials and interfaces
  • Analytical Methods in Pharmaceuticals
  • Gastric Cancer Management and Outcomes
  • Lipid Membrane Structure and Behavior
  • Garlic and Onion Studies
  • Agricultural Practices and Plant Genetics
  • Microbial Metabolites in Food Biotechnology
  • Advanced Thermoelectric Materials and Devices
  • Crystallization and Solubility Studies
  • Wound Healing and Treatments
  • Natural Antidiabetic Agents Studies

Imam Abdulrahman Bin Faisal University
2017-2024

JSS Academy of Higher Education and Research
2024

Ethiopian Institute of Agricultural Research
2021-2022

An-Najah National University
2019-2022

Cardiff University
2021

Navodaya Dental College and Hospital
2017

UNSW Sydney
1993-1994

The current study aimed to prepare a topical gel containing solid lipid nanoparticles (SLNs) encapsulating fluoxetine for diabetic wound healing effects. Fluoxetine (FX) was loaded into SLNs by employing an emulsion solvent evaporation technique using stearic acid as lipid, and soya lecithin surfactant. were then evaluated particle size, polydispersity index (PDI), zeta potential (ZP), percent entrapment efficiency (%EE), drug loading (%DL), in vitro release. optimized SLN (FS3) composed of...

10.3390/gels9010021 article EN cc-by Gels 2022-12-27

Meloxicam is a poorly water soluble non steroidal anti-inflammatory drug and antipyretic agent. The aim of the present work was to investigate effect different types carriers on in vitro dissolution meloxicam. solid dispersions were prepared by physical mixing, co-grinding solvent evaporation methods with polyethylene glycol (PEG) 6000. solubilization sodium lauryl sulphate (SLS) also studied. determined USP XXVII Apparatus I, using phosphate buffer pH 7.4 as medium. maximum meloxicam, i.e....

10.22037/ijpr.2010.682 article EN Iranian journal of pharmaceutical research 2010-11-20

The objective of this study was to synthesize silver nanoparticles from the leaves Tridax procumbens and develop its topical gels using chitosan investigate wound healing efficacy concomitant with histopathological study. Green synthesized (AgNPs) were prepared by reacting nitrate (0.3 M) leaf extract characterized particle analysis, FTIR, XRD, SEM, BET, TGA. results revealed formed AgNPs nano-sized (138 ± 2.1 nm), monodispersed (PDI: 0.460 0.3), inter-particle repulsion (zeta: -20.4 5.20...

10.3390/pharmaceutics13111754 article EN cc-by Pharmaceutics 2021-10-21

With various applications, Balanites aegyptiaca (Desert Date) is a traditional remedy for jaundice, intestinal worm infection, syphilis, malaria, dysentery amongst others but despite its good medicinal properties, it still considered lost crop because little or no attention has been put into using generation of modern medicines. Hexane and Methanol Extracts from seed Stem Bark the plant were analyzed presence phytochemicals extract isolates also Fourier Transform Infrared Spectrophotometer....

10.46602/jcsn.v50i1.1045 article EN Journal of Chemical Society of Nigeria 2025-02-23

The goal of the present work was to invent an apigenin-stacked gastroretentive microsponge target H. pylori. quasi-emulsion technique used prepare microsponges, which were then tested for various physicochemical properties, in-vivo gastric retention, and in-vitro anti-H. pylori study. that demonstrated a comparatively good product yield (76.23 ± 0.84), excellent entrapment efficiency (97.84 0.85), sustained retention period, prolonged drug release chosen further investigations. microsponge's...

10.1016/j.jsps.2023.03.006 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2023-03-13

The structural, elastic, electronic, magnetic, and thermoelectric properties of MgEu 2 X 4 (X = S Se) spinel compounds are investigated computationally. Calculations performed using the full‐potential linearized augmented plane wave (FP‐LAPW) method within Perdew, Burke, Ernzerhof generalized gradient approximation (PBE‐GGA), GGA + U, modified Becke–Johnson (mBJ‐GGA) approximations. band structure density states results from three exchange‐correlation methods (mBJ, PBE) show that these fully...

10.1002/pssb.202200191 article EN physica status solidi (b) 2022-07-27

The current study aimed to develop a luteolin gastric floating microsponge for targeting Helicobacter pylori. formulations were prepared by quasi-emulsion method, and then evaluated various physicochemical variables. best was further assessed drug-polymer interactions, surface morphology, in vivo floating, vitro anti H. pylori activity. formulation which exhibited comparatively good production yield (64.45% ± 0.83), high entrapment efficiency (67.33% 3.79), prolonged time (>8 h),...

10.3390/pharmaceutics13122094 article EN cc-by Pharmaceutics 2021-12-06

The phenomena of nonvolatile switching in amorphous-hydrogenated-silicon thin-film devices are explained by a theory based on the presence charged inclusions film, having originated from initial forming treatments. almost penetrate and able to move under applied fields sufficient magnitude, direction determined polarity. differences between analog digital ascribed homogeneity inclusions, being affected nature top contact.

10.1103/physrevb.49.13611 article EN Physical review. B, Condensed matter 1994-05-15

This research planned to ameliorate an aqueous solubility and dissolution of Curcumin (CUR) by the formulation inclusion complex with β-cyclodextrin (β-CD) polyvinylpyrrolidone (PVP). The phase study was performed assess CUR. prepared CUR assessed for study, physicochemical evaluation, in-vitro antioxidant activity, molecular modeling, anti-inflammatory assessment. pivotal findings phase-solubility studies demonstrate apparent stability constant (Kc) complexation efficiency (CE) values...

10.1080/03639045.2020.1810268 article EN Drug Development and Industrial Pharmacy 2020-08-19

Objective: The present study aimed to develop and optimize esomeprazole loaded proniosomes (EZL-PNs) improve bioavailability therapeutic efficacy. Method: EZL-PNs formulation was developed by slurry method optimized 33 box-Bhekhen statistical design software. Span 60 (surfactant), cholesterol, EZL concentration were taken as independent variables their effects evaluated on vesicle size (nm), entrapment efficiency (%, EE) drug release DR). Furthermore, (EZL-PNs-opt) for ex vivo permeation,...

10.3390/molecules27092748 article EN cc-by Molecules 2022-04-25
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