A5082716865- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Mosquito-borne diseases and control
- Diet and metabolism studies
- Health, Environment, Cognitive Aging
- Viral Infections and Vectors
- Cardiovascular Health and Risk Factors
- Birth, Development, and Health
- Long-Term Effects of COVID-19
- Andrographolide Research and Applications
- Vector-borne infectious diseases
- SARS-CoV-2 detection and testing
- Sepsis Diagnosis and Treatment
- Pharmacological Effects of Natural Compounds
Puer University
2024
Shanxi Medical University
2023
Shanghai Public Health Clinical Center
2020-2023
Shaanxi Provincial People's Hospital
2023
Qilu Hospital of Shandong University
2020
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
BackgroundNirmatrelvir plus ritonavir (Paxlovid) reduced the risk of hospitalization or death by 89% in high-risk, ambulatory adults with COVID-19. We aimed at studying efficacy and safety Paxlovid hospitalized adult patients SARS-Cov-2 (Omicron BA.2.2 variant) infection severe comorbidities.MethodsWe conducted an open-label, multicenter, randomized controlled trial which comorbidities were eligible assigned a 1:1 ratio to receive either 300 mg nirmatrelvir 100 every 12 h for 5 days standard...
Shufeng Jiedu capsules (SFJDC), a patented herbal drug composed of eight medicinal plants, is used for the treatment different viral respiratory tract infectious diseases. Based on its antiviral, anti-inflammatory and immunoregulatory activity in acute lung injury, SFJDC might be promising candidate COVID-19. To evaluate antiviral properties to discover mechanism action as potential Furthermore, study should determine clinical effectiveness We analyzed effects HCoV-229E mouse model index,...
Abstract Background Biological ageing is tightly linked to cardiovascular disease (CVD). We aimed investigate the relationship between Life’s Essential 8 (LE8), a currently updated measure of health (CVH), and biological ageing. Methods This cross-sectional study selected adults ≥ 20 years age from 2005–2010 National Health Nutrition Examination Survey. LE8 scores (range 0–100) were obtained measurements based on American Heart Association definitions, divided into behavior factor scores....
As the COVID-19 epidemic is still ongoing, a more rapid detection of SARS-CoV-2 infection such as viral antigen-detection needs to be evaluated for early diagnosis disease. Here, we report dynamic changes antigens in nasopharyngeal swabs patients and its association with nucleic acid clearance clinical outcomes. Eighty-five were enrolled antigens, including 57 anti-SARS-CoV-2 antibody negative cases 28 positive cases. The antigen could detected 52.63% (30/57) at stage infection, especially...
Abstract Background Tsutsugamushi, also known as bush typhus, is a naturally occurring disease caused by Orientia tsutsugamushi. We reported case of vertical mother-to-newborn transmission tsutsugamushi infection in newborn from Yunnan (China). Case presentation Decreased fetal movements were observed at 39 weeks gestation. After birth, the (female) had recurrent fever, shortness breath, and bruising around mouth extremities. At 5 h 58 min age, was admitted for breath generalized rash. The...