Janet H. Southerland

ORCID: 0000-0002-3612-4801
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About
Contact & Profiles
Research Areas
  • Oral microbiology and periodontitis research
  • Head and Neck Cancer Studies
  • Oral Health Pathology and Treatment
  • Oral health in cancer treatment
  • Intimate Partner and Family Violence
  • HIV/AIDS oral health manifestations
  • Dental Health and Care Utilization
  • Infective Endocarditis Diagnosis and Management
  • Elder Abuse and Neglect
  • Dental Education, Practice, Research
  • Salivary Gland Disorders and Functions
  • Global Health Workforce Issues
  • Streptococcal Infections and Treatments
  • Gut microbiota and health
  • Dental Anxiety and Anesthesia Techniques
  • Cervical Cancer and HPV Research
  • Cardiac Health and Mental Health
  • Child Abuse and Trauma
  • Cardiovascular Health and Risk Factors
  • Dental Radiography and Imaging
  • Grief, Bereavement, and Mental Health
  • Health Systems, Economic Evaluations, Quality of Life
  • Interprofessional Education and Collaboration
  • Blood Pressure and Hypertension Studies
  • Effects of Radiation Exposure

Louisiana State University Health Sciences Center New Orleans
2023-2024

The University of Texas Medical Branch at Galveston
2018-2022

Meharry Medical College
2011-2018

National Medical Research Center of Dentistry and Maxillofacial Surgery
2016

University of North Carolina at Chapel Hill
1993-2007

University of North Carolina Hospitals
2007

Triangle
2006

Research Triangle Park Foundation
2005

Levi Strauss (United States)
2004

IN BRIEF This review focuses on the relationship between diabetes and periodontal infection potential mechanisms involved in local systemic disease progression. In addition, various oral complications of are discussed, along with recommendations for management, treatment, proper referral.

10.2337/diaclin.23.4.171 article EN Clinical Diabetes 2005-10-01

Impaired colon motility is one of the leading problems associated with inflammatory bowel disease (IBD). An expanding body evidence supports role microbiome in normal gut function and progression IBD. The objective this work to determine whether diseased full thickness specimens, including neuromuscular region (critical for function), contain specific oral pathogens. In addition, we compared differences between Caucasians (CA) African Americans (AA). Thirty-nine human (diseased adjacent...

10.3389/fmicb.2018.03220 article EN cc-by Frontiers in Microbiology 2019-01-04

The early reports of a linkage between periodontitis and atherosclerosis have garnered further support by additional data generated several investigative teams in many different countries. evidence continues to suggest that may be an important risk factor or indicator for cardiovascular pathology some individuals. term periodontitis‐atherosclerosis syndrome (PAS) is proposed as new diagnostic describe this condition these Current evidence, albeit preliminary nature, which describes cluster...

10.1111/j.1600-0765.1999.tb02264.x article EN Journal of Periodontal Research 1999-10-01

This study assesses knowledge of oral cancer risk factors, clinical signs, and examination experience among North Carolina adults.A statewide random digit dial, computer-assisted telephone interview was conducted in 2002. Data from 1,096 respondents, with a response rate 62 percent, were poststratified to 2000 census data by sex, race, age group produce population-based estimates. Knowledge one sign cancer, four or more factors for having ever had an compared logistic regression models using...

10.1111/j.1752-7325.2004.tb02748.x article EN Journal of Public Health Dentistry 2004-09-01

The aim of this study was to determine the knowledge and practice behaviors one state's internists endocrinologists who treat patients with any type diabetes. A thirty‐five‐item questionnaire mailed 1,000 115 in North Carolina. Questions were open closed ended Likert‐scaled. Descriptive statistics bivariate analysis utilized. response rate 34 percent (N=378). overall usable 23 (N=254). Over half respondents (66 percent) males. Internists’ endocrinologists’ about periodontal disease high....

10.1002/j.0022-0337.2011.75.3.tb05046.x article EN Journal of Dental Education 2011-03-01

Variability in the widespread utilization and implementation of Interprofessional Education Collaborative's (IPEC) competency framework has highlighted importance institutional characteristics that serve as barriers and/or facilitators to progress, well absence evidence-based assessment instruments designed measure related constructs. Develop validate an instrument leverages IPEC identify associated with successful high-quality programmatic interprofessional education (IPE). A 16-member...

10.1016/j.xjep.2022.100553 article EN cc-by-nc-nd Journal of Interprofessional Education & Practice 2022-09-22

Objective The aim of this study was to determine active periodontal disease status in HIV and the impact resolution on status. Methods In longitudinal cohort study, 73 ‐positive subjects received comprehensive dental care. AAP , CDC / BGI case definitions determined classification. Likelihood frequency moderate/severe were assessed based demographic variables. influence intervention at baseline, 12, 24 months. IL ‐6 measured a subset subjects. Results Of classifications, demonstrated highest...

10.1111/odi.12419 article EN Oral Diseases 2016-04-01

Xerostomia is defined as dry mouth resulting from a change in the amount or composition of saliva and often major oral health complication associated with diabetes mellitus (DM). Studies have shown that xerostomia more common females at onset DM. Evidence suggests nitric oxide (NO) plays critical role healthy salivary gland function. However, specific mechanisms by which NO regulates function DM yet to be determined. This study has two aims: 1) determine whether protein expression...

10.1902/jop.2016.150639 article EN Journal of Periodontology 2016-01-16

Periodontal disease is a highly prevalent chronic inflammatory and associated with complex microbial infection in the subgingival cavity. Recently, American Heart Association supported century old association between periodontal atherosclerotic vascular disease. We have recently shown that polybacterial led to aortic atherosclerosis modulation of lipid profiles; however underlying mechanism(s) has not been yet demonstrated. Altered nitric oxide (NO) synthesis tetrahydrobiopterin (BH4),...

10.1371/journal.pone.0129885 article EN cc-by PLoS ONE 2015-06-25

We describe 2 nonsmoking, nondrinking couples who developed human papillomavirus (HPV)–associated tonsillar cancer within 12 months of each other. After histopathologic evaluation, HPV L1, E2, E6, and LCR regions were amplified, phylogenetic analysis amplimers was determined. Quantitative polymerase chain reaction targeting HPV-16/18 L1 E7 P16 immunohistochemistry performed. Tissues HPV-16 positive, with distinct intercouple nucleotide differences multiple unique intracouple similarities...

10.1086/605442 article EN The Journal of Infectious Diseases 2009-08-13

Periodontal ligament (PDL) cells have been shown to express several integrins (α v , α 5 β 1 3 ) that use RGD (arginine-glycine-aspartic Acid)-dependent mechanisms for the recognition and binding of their ligands. The objective this study was evaluate effects certain integrin-binding cyclic linear synthetic RGD-containing peptides on PDL cells' adhesion, proliferation, de novo protein synthesis in vitro. Fifth passages normal human established from teeth extracted patients (ages 12 14)...

10.1177/00220345980770080801 article EN Journal of Dental Research 1998-08-01
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