A5000130037- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Crystal structures of chemical compounds
- Synthesis and biological activity
- Chemical Reaction Mechanisms
- Crystallography and molecular interactions
- Free Radicals and Antioxidants
- Organic Light-Emitting Diodes Research
- Luminescence and Fluorescent Materials
- Metal complexes synthesis and properties
- Analytical Chemistry and Chromatography
- Photochemistry and Electron Transfer Studies
- Synthesis and Characterization of Heterocyclic Compounds
- Organic Electronics and Photovoltaics
- Coordination Chemistry and Organometallics
- Asymmetric Synthesis and Catalysis
- Conducting polymers and applications
- DNA and Nucleic Acid Chemistry
- Surfactants and Colloidal Systems
- Computational Drug Discovery Methods
- Radical Photochemical Reactions
- Synthesis and Biological Evaluation
- Metal-Organic Frameworks: Synthesis and Applications
- Chemical Synthesis and Analysis
- Oxidative Organic Chemistry Reactions
University of Malaya
2015-2024
Kaunas University of Technology
2020-2024
Hospital Kuala Lumpur
2015-2020
Malaysian Palm Oil Board
2018
University of Nottingham
1998-2000
A computer-aided predictions of antioxidant activities were performed with the Prediction Activity Spectra Substances (PASS) program. Antioxidant activity compounds 1, 3, 4 and 5 studied using 1,1-diphenyl-2-picrylhydrazyl (DPPH) lipid peroxidation assays to verify obtained by PASS Compounds 3 showed more inhibition DPPH stable free radical at 10−4 M than well-known standard antioxidant, butylated hydroxytoluene (BHT). Compound exhibited promising in vitro Fe2+-induced essential egg yolk as...
A new series of multipotent antioxidants (MPAOs), namely Schiff base-1,2,4-triazoles attached to the oxygen-derived free radical scavenging moiety butylated hydroxytoluene (BHT) were designed and subsequently synthesized. The structure-activity relationship (SAR) was established alongside prediction activity spectra for substances (PASS). antioxidant activities synthesized compounds 4–10 tested by DPPH bioassay. inhibited stable radicals at a level that is 10−4 M more than well-known...
Impacts of intramolecular non-covalent interactions TADF emitters on their electroluminescent performances were investigated using donor-acceptor compounds containing moiety 1,4-bis(trifluoromethyl)benzene.
The red-shift of triplet energies between the dilute phase and solid states is a function intermolecular distance.
Eleven new 2,6-di-tert-butyl-4-(5-aryl-1,3,4-oxadiazol-2-yl)phenols 5a–k were synthesized by reacting aryl hydrazides with 3,5-di-tert butyl 4-hydroxybenzoic acid in the presence of phosphorus oxychloride. The resulting compounds characterized based on their IR, 1H-NMR, 13C-NMR, and HRMS data. 2,2-Diphenyl-1-picrylhydrazide (DPPH) ferric reducing antioxidant power (FRAP) assays used to test properties compounds. Compounds 5f 5j exhibited significant free-radical scavenging ability both assays.
Poly(3,4-ethylenedioxythiophene)polystyrene sulfonate (PEDOT:PSS) is often used as a hole injection and extractor for various organic electronic devices. This study investigated whether it possible to n-dope PEDOT:PSS with barium acetylacetonate (Ba(acac)2) change its work function so that be more suitable electron extraction. Molecular dynamics simulations suggested cations can interact the aromatic rings of PEDOT negatively charged in PSS. At high doping concentration, we found became...
New thiosemicarbazide derivatives 2–6 were synthesised by reacting 2-(ethylsulfanyl)benzohydrazide with various aryl isothiocyanates. The cyclisation of compounds under reflux conditions in a basic medium (aqueous NaOH, 4 N) yielded 7–11 that contain 1,2,4-triazole ring. All the screened for their antioxidant activities. Compounds 2, 3, and 7 showed better radical scavenging 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, IC50 values 1.08, 0.22, 0.74 µg/mL, respectively, compared to gallic acid...
By alternating high aromaticity and reduced in an extended fused π-system, a triplet energy can be obtained.
A series of heterocyclic compounds bearing the well-known free radical scavenging 3,4,5-trimethoxybenzyloxy group, was synthesized. The key compound 4-(3,4,5-trimethoxybenzyl-oxy)benzohydrazide converted into thiosemicarbazide derivatives, which were subsequently cyclized with NaOH to provide 1,2,4-triazole derivatives. Alternative treatment acid hydrazide carbon disulfide in presence KOH led corresponding 1,3,4-oxadiazole and various alkylated newly synthesized purified structures products...
A series of new 2-(ethylthio)benzohydrazone derivatives (1-6) were prepared and characterised by IR, 1H NMR, 13C NMR spectroscopy mass spectrometry. The newly compounds screened for their in vitro antioxidant activities using free radical scavenging 2,2-diphenyl-1-picrylhydrazyl (DPPH) ferric reducing power (FRAP) assays. Among them, most powerful antioxidant, compound 1 has been selected order to illustrate anti-ulcer effect on ethanol-induced gastric mucosal lesions rats. Four groups...
Two series of 1,3,4-oxadiazole derivatives at the sixth position 2,4-di- tert -butylphenol group were synthesized.
The rates of the hydrolyses N-(o-hydroxyphenyl)phthalimide (1) and N-(o-methoxyphenyl)phthalimide (2), studied at different pH, show that hydrolysis 1 involves intramolecular general base (IGB) assistance where o-O- group ionized acts as IGB H2O reactant. rate enhancement due to IGB-assisted reaction with is >8 × 104-fold. Pseudo-first-order constant for water 2 ∼2 103-fold smaller than first-order (0.10 s-1) pH-independent within pH range 9.60−10.10. Second-order constants (kOH) hydroxide...
Three new, closely similar Pb-based organic frameworks synthesized using a simple and optimized dissolution–crystallization method with benzene-1,3,5-tricarboxylic acid (H3BTC) are reported along their structural characterizations photoluminescent properties. Compound 1, Pb(HBTC)(1,4-dioxane)0.5, crystallizes in the C2/c space group (a = 17.239(2) Å, b 7.0225(8) c 19.911(2) β 104.735(10)°); compound 2, Pb2(HBTC)2(H2O)5, P1̅ 7.3989(4) 8.2196(4) 10.1437(5) α 94.336(4)°, 104.943(4)°, γ...
A series of carbazole-thiophene dimers, P1–P9 , were synthesized using Suzuki-Miyaura and Ullmann coupling reactions. In carbazole-thiophenes linked at the N-9 position for different core groups via biphenyl, dimethylbiphenyl, phenyl. Electronic properties evaluated by UV-Vis, cyclic voltammogram, theoretical calculations. Particularly, effects conjugation connectivity on photophysical electrochemical properties, as well correlation between core, studied. Carbazole connecting with thiophenes...